Effect of PCBs on the lactational transfer of methyl mercury in mice: PBPK modeling

Environmental Toxicology and Pharmacology

Volumn 27, Issue 1, 2009, Pages 75-83

  Lee, Sun Ku ^a   Hamer, Dwayne ^a   Bedwell, Cathy L ^a   Lohitnavy, Manupat ^a   Yang, Raymond S H ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Lactational transfer; MeHg; PBPK; PCBs

Indexed keywords

ALBUMIN; POLYCHLORINATED BIPHENYL;

ALBUMIN BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; LACTATION; MALE; MATERNAL BLOOD; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE LEVEL; TOXICOKINETICS;

MUS;

EID: 57149127661     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2008.08.014     Document Type: Article

References (45)

1. Bemis J.C., and Seegal R.F. Polychlorinated biphenyls and methylmercury act synergistically to reduce rat brain dopamine content in vitro. Environ. Health Perspect. 107 (1999) 879-885
2. Bemis J.C., and Seegal R.F. Polychlorinated biphenyls and methylmercury alter intracellular calcium concentrations in rat cerebellar granule cells. Neurotoxicology 21 (2000) 1123-1134
3. Boersma E.R., and Lanting C.I. Environmental exposure to polychlorinated biphenyls (PCBs) and dioxins. Consequences for long-term neurological and cognitive development of the child lactation. Adv. Exp. Med. Biol. 478 (2000) 271-287
4. Borlak J., Dangers M., and Thum T. Aroclor 1254 modulates gene expression of nuclear transcription factors: implications for albumin gene transcription and protein synthesis in rat hepatocyte cultures. Toxicol. Appl. Pharmacol. 181 (2002) 79-98
5. Bowers W.J., Nakai J.S., Chu I., Wade M.G., Moir D., Yagminas A., Gill S., Pulido O., and Meuller R. Early developmental neurotoxicity of a PCB/organochlorine mixture in rodents after gestational and lactational exposure. Toxicol. Sci. 77 (2004) 51-62
6. Brown R.P., Delp M.D., Lindstedt S.L., Rhomberg L.R., and Beliles R.P. Physiological parameter values for physiologically based pharmacokinetic models. Toxicol. Ind. Health 13 (1997) 407-484
7. Buck G.M. Epidemiologic perspective of the developmental neurotoxicity of PCBs in humans. Neurotoxicol. Teratol. 18 (1996) 239-241
8. Burbacher T.M., Rodier P.M., and Weiss B. Methylmercury developmental neurotoxicity: a comparison of effects in humans and animals. Neurotoxicol. Teratol. 12 (1990) 191-202
9. Byczkowski J.Z., and Lipscomb J.C. Physiologically based pharmacokinetic modeling of the lactational transfer of methylmercury. Risk Anal. 21 (2001) 869-882
10. Carpenter D.O. Polychlorinated biphenyls (PCBs): routes of exposure and effects on human health. Rev. Environ. Health. 21 (2006) 1-23
11. Corley R.A., Mast T.J., Carney E.W., Rogers J.M., and Daston G.P. Evaluation of physiologically based models of pregnancy and lactation for their application in children's health risk assessments. Crit. Rev. Toxicol. 33 (2003) 137-211
12. Davidson P.W., Myers G.J., Weiss B., Shamlaye C.F., and Cox C. Prenatal methyl mercury exposure from fish consumption and child development: a review of evidence and perspectives from Seychelles child development study. Neurotoxicology 27 (2006) 1106-1109
13. De Guise S., Shaw S.D., Barclay J.S., Brock J., Brouwer A., Dewailly E., Fair P.A., Fournier M., Grandjean P., Guillette Jr. L.J., Hahn M.E., Koopman-Esseboom C., Letcher R.J., Matz A., Norstrom R.J., Perkins C.R., Schwacke L., Skaare J.U., Sowles J., St Aubin D.J., Stegeman J., and Whaley J.E. Consensus statement: Atlantic Coast Contaminants Workshop 2000. Environ. Health Perspect. 109 (2001) 1301-1302
14. Eriksson P. Developmental neurotoxicity of environmental agents in the neonate. Neurotoxicology 18 (1997) 719-726
15. Geursen A., and Grigor M.R. Serum albumin secretion in milk. J. Physiol. 391 (1986) 419-427
16. Gochfeld M. Cases of mercury exposure, bioavailability, and absorption. Ecotoxicol. Environ. Saf. 56 (2003) 174-179
17. Grandjean P., Weihe P., Burse V.W., Needham L.L., Storr-Hansen E., Heinzow B., Debes F., Muraka K., Simonsen H., Ellefsen P., Budtz-Jorgensen E., Keiding N., and White R.F. Neurobehavioral deficits associated with PCB in 7-year old children prenatally exposed to seafood toxicants. Neurotoxicol. Teratol. 23 (2001) 305-317
18. Lee S.K., Ou Y.C., and Yang R.S. Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and suckling pups. Toxicol. Sci. 65 (2002) 26-34
19. Lee S.K., Ou Y.C., Andersen M.E., and Yang R.S. A physiologically based pharmacokinetic model for lactational transfer of PCB 153 with or without PCB 126 in mice. Arch. Tox. 81 (2007) 101-111
20. Mahaffey K.R. Recent advances in recognition of low-level methylmercury poisoning. Curr. Opin. Neurol. 13 (2000) 699-707
21. Matthews H.B., Kato S., Morales N.M., and Tuey D.B. Distribution and excretion of 2,4,5,2′,4′,5′-hexabromobiphenyl, the major component of Firemaster BP-6. J. Toxicol. Environ. Health 3 (1977) 599-605
22. McMullin T.S., Brzezicki J.M., Cranmer B.K., Tessari J.D., and Andersen M.E. Pharmacokinetic modeling of disposition and time-course studies with [14C]atrazine. J. Toxicol. Environ. Health A 66 (2003) 941-964
23. Myers G.J., Davidson P.W., Cox C., Shamlaye C., Cernichiari E., and Clarkson T.W. Twenty-seven years studying the human neurotoxicity of methylmercury exposure. Environ. Res. 83 (2000) 275-285
24. Nakai K., and Satoh H. Developmental neurotoxicity following prenatal exposures to methylmercury and PCBs in humans from epidemiological studies. Tohoku. J. Exp. Med. 196 (2002) 89-98
25. National Research Council. Toxicological Effects of Methyl Mercury (2000), National Academy Press, Washington, DC
26. Newland M.C., and Paletz E.M. Animal studies of methylmercury and PCBs: what do they tell us about expected effects in humans?. Neurotoxicology 21 (2000) 1003-1028
27. Nordenhall K., Dock L., and Vahter M. Transplacental and lactational exposure to mercury in hamster pups after maternal administration of methyl mercury in late gestation. Pharmacol. Toxicol. 77 (1995) 130-135
28. Oskarsson A., Hallen I., Sundberg J., and Grawe K. Risk assessment in relation to neonatal metal exposure. Analyst 123 (1998) 19-23
29. Pitkin R.M., Bahns J.A., Filer Jr. L.J., and Reynolds W.A. Mercury in human maternal and cord blood, placenta, and milk. Proc. Soc. Exp. Biol. Med. 151 (1976) 565-567
30. Rice D.C. Neurotoxicity of lead, methylmercury, and PCBs in relation to the Great Lakes. Environ. Health Perspect. 103 Suppl. 9 (1995) 71-87
31. Risher J.F., Murray H.E., and Prince G.R. Organic mercury compounds: human exposure and its relevance to public health. Toxicol. Ind. Health 18 (2002) 109-160
32. Ritter L., Solomon K., Sibley P., Hall K., Keen P., Mattu G., and Linton B. Sources, pathways, and relative risks of contaminants in surface water and groundwater: a perspective prepared for the Walkerton inquiry. J. Toxicol. Environ. Health A 65 (2002) 1-142
33. Ronchetti R., Zuurbier M., Jenenak M., Koppe J.G., Farah U., Ceccatelli S., and Pia Villa M. Children's health and mercury exposure. Acta Pediatr. 95 (2006) 36-44
34. Safe S.H. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Crit. Rev. Toxicol. 24 (1994) 87-149
35. Smith F.A., Sharma R.P., Lynn R.I., and Low J.B. Mercury and selected pesticide levels in fish and wild life of Utah: I. levels of mercury, DDT, DDE, dieldrin, and PCB in fish. Bull. Environ. Contamin. Toxicol. 12 (1974) 218-223
36. Smoley C.K. Methods for the determination of metals in environmental samples, determination of mercury in tissues by cold vapor atomic absorption spectrometry. In: EPA U. (Ed). EPA Method (1992), Environmental Monitoring Systems Laboratory, Office of Research and Development, US EPA, Cincinnati 1-212
37. Spindler-Vomachka M., Vodicnik M.J., and Lech J.J. Transport of 2,4,5,2′,4′,5′-hexachlorobiphenyl by lipoproteins in vivo. Toxicol. Appl. Pharmacol. 74 (1984) 70-77
38. Strathmann J., Schwarz M., Tharappel J.C., Glauert H.P., Spear B.T., Robertson L.W., Appel K.E., and Buchmann A. PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumors. Toxicol. Sci. 93 (2006) 34-40
39. Sundberg J., Ersson B., Lonnerdal B., and Oskarsson A. Protein binding of mercury in milk and plasma from mice and man-a comparison between methylmercury and inorganic mercury. Toxicology 137 (1999) 169-184
40. Sundberg J., Jonsson S., Karlsson M.O., Hallen I.P., and Oskarsson A. Kinetics of methylmercury and inorganic mercury in lactating and nonlactating mice. Toxicol. Appl. Pharmacol. 151 (1998) 319-329
41. Tietz N. Fundamentals of Clinical Chemistry (1970), WB Saunders & Co., Philidelphia
42. Tilson H.A., and Kodavanti P.R. Neurochemical effects of polychlorinated biphenyls: an overview and identification of research needs. Neurotoxicology 18 (1997) 727-743
43. Van Birgelen A.P., Fase K.M., Van der Kolk J., Poiger H., Brouwer A., Seinen W., and Van den Berg M. Synergistic effect of 2,2′,4,4′,5,5′-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat. Environ. Health Perspect. 104 (1996) 550-557
44. Vodicnik M.J., and Lech J.J. The transfer of 2,4,5,2′,4′,5′-hexachlorobiphenyl to fetuses and nursing offspring. I. Disposition in pregnant and lactating mice and accumulation in young. Toxicol. Appl. Pharmacol. 54 (1980) 293-300
45. Yasutake A., Hirayama K., and Inoue M. Mechanism of urinary excretion of methylmercury in mice. Arch. Toxicol. 63 (1989) 479-483