Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis

Circulation

Volumn 118, Issue 20, 2008, Pages 2063-2072

  Kaya, Ziya ^a   Göser, Stefan ^a   Buss, Sebastian J ^a   Leuschner, Florian ^a   Öttl, Renate ^a   Li, Jin ^a   Völkers, Mirko ^a   Zittrich, Stefan ^b   Pfitzer, Gabriele ^b   Rose, Noel R ^c   Katus, Hugo A ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF COLOGNE   (Germany)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Heart failure; Immunology; Inflammation; Myocarditis; Troponin

Indexed keywords

CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5; EOTAXIN; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 2; PEPTIDE DERIVATIVE; RANTES; TROPONIN I; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIBODY TITER; ARTICLE; CELL TRANSFER; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; HEART FAILURE; HEART MUSCLE FIBROSIS; HUMORAL IMMUNITY; IMMUNIZATION; MOUSE; MYOCARDITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; T LYMPHOCYTE ACTIVATION; WILD TYPE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; ANTIBODY FORMATION; AUTOIMMUNITY; BONE AND BONES; CHEMOKINES; FEMALE; FIBROSIS; HEART FAILURE; HUMANS; IMMUNIZATION; MICE; MICE, INBRED STRAINS; MICE, SCID; MOLECULAR CONFORMATION; MYOCARDITIS; MYOCARDIUM; PEPTIDE FRAGMENTS; RECEPTORS, CHEMOKINE; SEQUENCE ANALYSIS, PROTEIN; SPLEEN; T-LYMPHOCYTES; TROPONIN I;

EID: 57149123541     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.108.788711     Document Type: Article

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