Regulatory light chain mutations associated with cardiomyopathy affect myosin mechanics and kinetics

Journal of Molecular and Cellular Cardiology

Volumn 46, Issue 1, 2009, Pages 108-115

  Greenberg, Michael J ^a   Watt, James D ^a   Jones, Michelle ^b   Kazmierczak, Katarzyna ^b   Szczesna Cordary, Danuta ^b   Moore, Jeffrey R ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

ATPase; Calcium binding site; FHC; Motility assay; Optical trapping; RLC

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CALCIUM; MYOSIN; N47K PROTEIN; PROTEIN DERIVATIVE; R58Q PROTEIN; UNCLASSIFIED DRUG;

ACTIN FILAMENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; FORCE; HEART; HEART HYPERTROPHY; HEART MUSCLE RELAXATION; IN VITRO STUDY; KINETICS; LIGHT CHAIN; MALE; MECHANICS; MOUSE; MUTATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PURIFICATION; TRANSGENIC MOUSE; WILD TYPE;

ACTINS; ADENOSINE TRIPHOSPHATASES; ANIMALS; BINDING SITES; CARDIOMYOPATHIES; CHICKENS; HUMANS; KINETICS; MICE; MICE, TRANSGENIC; MUSCLE, SKELETAL; MUTATION; MYOSIN LIGHT CHAINS; MYOSINS; SWINE;

MUS MUSCULUS;

EID: 57149087461     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2008.09.126     Document Type: Article

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