-
1
-
-
0036359548
-
Hypoxia: A key regulatory factor in tumor growth
-
Harris, A. L. (2002) Hypoxia: A key regulatory factor in tumor growth. Nat Rev Cancer, 2, pp. 38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
2
-
-
77956940478
-
Lactate dehydrogenase
-
Academic Press, NY
-
Holbrook, J. J., Liljas, A., Steindel, S. J. and Rossman, M. G. (1975) Lactate dehydrogenase. The Enzymes, Vol. XI, pp. 191-292. Academic Press, NY
-
(1975)
The Enzymes
, vol.11
, pp. 191-292
-
-
Holbrook, J.J.1
Liljas, A.2
Steindel, S.J.3
Rossman, M.G.4
-
3
-
-
0030460724
-
Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1
-
Semenza, G. L., Jiang, B. H., Leung, S. W., Passantino, R., Concordet, J. P. Maire, P. et al. (1996) Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor 1. J Biol Chem, 271, pp. 32529-32537.
-
(1996)
J Biol Chem
, vol.271
, pp. 32529-32537
-
-
Semenza, G.L.1
Jiang, B.H.2
Leung, S.W.3
Passantino, R.4
Concordet, J.P.5
Maire, P.6
-
4
-
-
0344197042
-
Tumour and angiogenesis research group. Lactate dehydrogenase isoenzymes 1 and 5: Differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors
-
Koukourakis, M. I., Giatromanolaki, A. and Sivridis, E. (2003) Tumour and angiogenesis research group. Lactate dehydrogenase isoenzymes 1 and 5: Differential expression by neoplastic and stromal cells in non-small cell lung cancer and other epithelial malignant tumors. Tumor Biol, 24, pp. 199-202.
-
(2003)
Tumor Biol
, vol.24
, pp. 199-202
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
-
5
-
-
33846531961
-
Incidence and risk factors of central nervous system recurrence in aggressive lymphoma - A survey of 1693 patients treated in protocols of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
-
German high-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL)
-
Boehme, V., Zeynalova, S., Kloess, M., Loeffler, M., Kaiser, U. Pfreundschuh, M. et al. (2007) German high-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). Incidence and risk factors of central nervous system recurrence in aggressive lymphoma - a survey of 1693 patients treated in protocols of the German High-Grade Non-Hodgkin's Lymphoma Study Group (DSHNHL). Ann Oncol, 18, pp. 149-157.
-
(2007)
Ann Oncol
, vol.18
, pp. 149-157
-
-
Boehme, V.1
Zeynalova, S.2
Kloess, M.3
Loeffler, M.4
Kaiser, U.5
Pfreundschuh, M.6
-
6
-
-
0141838872
-
Stage III follicular lymphoma: Long-term follow-up and patterns of failure
-
Ha, C. S., Kong, J. S., McLaughlin, P., Tucker, S. L., Fayad, L. E. Hess, M. A. et al. (2003) Stage III follicular lymphoma: Long-term follow-up and patterns of failure. Int J Radiat Oncol Biol Phys, 57, pp. 748-754.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.57
, pp. 748-754
-
-
Ha, C.S.1
Kong, J.S.2
McLaughlin, P.3
Tucker, S.L.4
Fayad, L.E.5
Hess, M.A.6
-
7
-
-
0034284050
-
Prognostic significance of survivin expression in diffuse large B-cell lymphomas
-
Adida, C., Haioun, C., Gaulard, P., Lepage, E., Morel, P. Briere, J. et al. (2000) Prognostic significance of survivin expression in diffuse large B-cell lymphomas. Blood, 96, pp. 1921-1925.
-
(2000)
Blood
, vol.96
, pp. 1921-1925
-
-
Adida, C.1
Haioun, C.2
Gaulard, P.3
Lepage, E.4
Morel, P.5
Briere, J.6
-
8
-
-
7344221466
-
Peripheral T-cell lymphomas: Initial features, natural history, and prognostic factors in a series of 174 patients diagnosed according to the R.E.A.L. Classification
-
López-Guillermo, A., Cid, J., Salar, A., López, A., Montalbán, C. Castrillo, J. M. et al. (1998) Peripheral T-cell lymphomas: Initial features, natural history, and prognostic factors in a series of 174 patients diagnosed according to the R.E.A.L. Classification. Ann Oncol, 9, pp. 849-855.
-
(1998)
Ann Oncol
, vol.9
, pp. 849-855
-
-
López-Guillermo, A.1
Cid, J.2
Salar, A.3
López, A.4
Montalbán, C.5
Castrillo, J.M.6
-
9
-
-
58949086093
-
Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin lymphomas and correlate with hypoxia inducible factor activation
-
Giatromanolaki, A., Koukourakis, M. I., Pezzella, F., Sivridis, E., Turley, H. Harris, A. L. et al. Phosphorylated VEGFR2/KDR receptors are widely expressed in B-cell non-Hodgkin lymphomas and correlate with hypoxia inducible factor activation. Hematol Oncol
-
Hematol Oncol
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Pezzella, F.3
Sivridis, E.4
Turley, H.5
Harris, A.L.6
-
10
-
-
0033571939
-
Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-induciblefactor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin
-
Zaman, K., Ryu, H., Hall, D., O'Donovan, K., Lin, K. I. Miller, M. P. et al. (1999) Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-induciblefactor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, p21(waf1/cip1), and erythropoietin. J Neurosci, 19, pp. 9821-9830.
-
(1999)
J Neurosci
, vol.19
, pp. 9821-9830
-
-
Zaman, K.1
Ryu, H.2
Hall, D.3
O'Donovan, K.4
Lin, K.I.5
Miller, M.P.6
-
11
-
-
31544445490
-
Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma
-
Koukourakis, M. I., Giatromanolaki, A., Harris, A. L. and Sivridis, E. (2006) Comparison of metabolic pathways between cancer cells and stromal cells in colorectal carcinomas: A metabolic survival role for tumor-associated stroma. Cancer Res, 66, pp. 632-637.
-
(2006)
Cancer Res
, vol.66
, pp. 632-637
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Harris, A.L.3
Sivridis, E.4
-
12
-
-
0033870281
-
The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages
-
Talks, K. L., Turley, H., Gatter, K. C., Maxwell, P. H., Pugh, C. W. Ratcliffe, P. J. et al. (2000) The expression and distribution of the hypoxia-inducible factors HIF-1α and HIF-2α in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol, 157, pp. 411-421.
-
(2000)
Am J Pathol
, vol.157
, pp. 411-421
-
-
Talks, K.L.1
Turley, H.2
Gatter, K.C.3
Maxwell, P.H.4
Pugh, C.W.5
Ratcliffe, P.J.6
-
13
-
-
0031759488
-
Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1
-
Turley, H., Scott, P. A., Watts, V. M., Bicknell, R., Harris, A. L. and Gatter, K. C. (1998) Expression of VEGF in routinely fixed material using a new monoclonal antibody VG1. J Pathol, 186, pp. 313-318.
-
(1998)
J Pathol
, vol.186
, pp. 313-318
-
-
Turley, H.1
Scott, P.A.2
Watts, V.M.3
Bicknell, R.4
Harris, A.L.5
Gatter, K.C.6
-
14
-
-
10744227994
-
The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study
-
Stewart, M., Turley, H., Cook, N., Pezzella, F., Pillai, G. Ogilvie, D. et al. (2003) The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study. Histopathology, 43, pp. 33-39.
-
(2003)
Histopathology
, vol.43
, pp. 33-39
-
-
Stewart, M.1
Turley, H.2
Cook, N.3
Pezzella, F.4
Pillai, G.5
Ogilvie, D.6
-
15
-
-
0025126502
-
JC70: A new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections
-
Parums, D. V., Cordell, J. L., Micklem, K., Heryet, A. R., Gatter, K. C. and Mason, D. Y. (1990) JC70: A new monoclonal antibody that detects vascular endothelium associated antigen on routinely processed tissue sections. J Clin Pathol, 43, pp. 752-757.
-
(1990)
J Clin Pathol
, vol.43
, pp. 752-757
-
-
Parums, D.V.1
Cordell, J.L.2
Micklem, K.3
Heryet, A.R.4
Gatter, K.C.5
Mason, D.Y.6
-
16
-
-
33751430258
-
Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis
-
Tumour and Angiogenesis Research Group
-
Giatromanolaki, A., Sivridis, E., Gatter, K. C., Turley, H., Harris, A. L. and Koukourakis, M. I. (2006) Tumour and Angiogenesis Research Group. Lactate dehydrogenase 5 (LDH-5) expression in endometrial cancer relates to the activated VEGF/VEGFR2(KDR) pathway and prognosis. Gynecol Oncol, 103, pp. 912-918.
-
(2006)
Gynecol Oncol
, vol.103
, pp. 912-918
-
-
Giatromanolaki, A.1
Sivridis, E.2
Gatter, K.C.3
Turley, H.4
Harris, A.L.5
Koukourakis, M.I.6
-
17
-
-
33749027749
-
Lactate dehydrogenase 5 expression in operable colorectal cancer: Strong association with survival and activated vascular endothelial growth factor pathway - A report of the Tumour Angiogenesis Research Group
-
Tumour Angiogenesis Research Group
-
Koukourakis, M. I., Giatromanolaki, A., Sivridis, E., Gatter, K. C. and Harris, A. L. (2006) Tumour Angiogenesis Research Group. Lactate dehydrogenase 5 expression in operable colorectal cancer: Strong association with survival and activated vascular endothelial growth factor pathway - a report of the Tumour Angiogenesis Research Group. J Clin Oncol, 24, pp. 4301-4308.
-
(2006)
J Clin Oncol
, vol.24
, pp. 4301-4308
-
-
Koukourakis, M.I.1
Giatromanolaki, A.2
Sivridis, E.3
Gatter, K.C.4
Harris, A.L.5
-
18
-
-
0031945961
-
Focal expression of thymidine phosphorylase associates with CD31 positive lymphocytic aggregation and local neo-angiogenesis in non-small cell lung cancer
-
Giatromanolaki, A., Koukourakis, M. I., Kakolyris, S., Kaklamanis, L., Barbatis, K. O'Byrne, K. J. et al. (1998) Focal expression of thymidine phosphorylase associates with CD31 positive lymphocytic aggregation and local neo-angiogenesis in non-small cell lung cancer. Anticancer Res, 18, pp. 71-76.
-
(1998)
Anticancer Res
, vol.18
, pp. 71-76
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Kakolyris, S.3
Kaklamanis, L.4
Barbatis, K.5
O'Byrne, K.J.6
-
19
-
-
0031409283
-
Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer
-
Giatromanolaki, A., Koukourakis, M. I., Theodossiou, D., Barbatis, K., O'Byrne, K. Harris, A. L. et al. (1997) Comparative evaluation of angiogenesis assessment with anti-factor-VIII and anti-CD31 immunostaining in non-small cell lung cancer. Clin Cancer Res, 3, pp. 2485-2492.
-
(1997)
Clin Cancer Res
, vol.3
, pp. 2485-2492
-
-
Giatromanolaki, A.1
Koukourakis, M.I.2
Theodossiou, D.3
Barbatis, K.4
O'Byrne, K.5
Harris, A.L.6
-
20
-
-
41049089464
-
Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase
-
Koiri, R. K., Trigun, S. K., Dubey, S. K., Singh, S. and Mishra, L. (2008) Metal Cu(II) and Zn(II) bipyridyls as inhibitors of lactate dehydrogenase. Biometals, 21, pp. 117-119.
-
(2008)
Biometals
, vol.21
, pp. 117-119
-
-
Koiri, R.K.1
Trigun, S.K.2
Dubey, S.K.3
Singh, S.4
Mishra, L.5
-
21
-
-
33846352097
-
A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical benefit on progression-free survival (PFS) in high LDH pts
-
Major, P., Trarbach, T., Lenz, H., Kerr, D., Pendergrass, K. Douillard, J. et al. A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical benefit on progression-free survival (PFS) in high LDH pts. J Clin Oncol
-
J Clin Oncol
-
-
Major, P.1
Trarbach, T.2
Lenz, H.3
Kerr, D.4
Pendergrass, K.5
Douillard, J.6
-
22
-
-
0003477486
-
Pathology and genetics
-
WHO Classification of Tumors Lyon: IARC
-
WHO Classification of Tumors (2001) Pathology and genetics. Tumors of Hematopoietic and Lymphoid Tissues. Lyon: IARC
-
(2001)
Tumors of Hematopoietic and Lymphoid Tissues
-
-
-
23
-
-
11344251539
-
Increased vascularization predicts favorable outcome in follicular lymphoma
-
Koster, A., van Krieken, J. H., Mackenzie, M. A., Schraders, M., Borm, G. F. van der Laak, J. A. et al. (2005) Increased vascularization predicts favorable outcome in follicular lymphoma. Clin Cancer Res, 11, pp. 154-161.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 154-161
-
-
Koster, A.1
van Krieken, J.H.2
Mackenzie, M.A.3
Schraders, M.4
Borm, G.F.5
van der Laak, J.A.6
-
24
-
-
33746290180
-
Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis
-
Ganjoo, K. N., An, C. S., Robertson, M. J., Gordon, L. I., Sen, J. A. Weisenbach, J. et al. (2006) Rituximab, bevacizumab and CHOP (RA-CHOP) in untreated diffuse large B-cell lymphoma: Safety, biomarker and pharmacokinetic analysis. Leuk Lymphoma, 47, pp. 998-1005.
-
(2006)
Leuk Lymphoma
, vol.47
, pp. 998-1005
-
-
Ganjoo, K.N.1
An, C.S.2
Robertson, M.J.3
Gordon, L.I.4
Sen, J.A.5
Weisenbach, J.6
-
25
-
-
34249873257
-
Angiogenesis in nodal B cell lymphomas: A high throughput study
-
Tzankov, A., Heiss, S., Ebner, S., Sterlacci, W., Schaefer, G. Augustin, F. et al. (2007) Angiogenesis in nodal B cell lymphomas: A high throughput study. J Clin Pathol, 60, pp. 476-482.
-
(2007)
J Clin Pathol
, vol.60
, pp. 476-482
-
-
Tzankov, A.1
Heiss, S.2
Ebner, S.3
Sterlacci, W.4
Schaefer, G.5
Augustin, F.6
-
26
-
-
37549055122
-
Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy
-
Gratzinger, D., Zhao, S., Tibshirani, R. J., Hsi, E. D., Hans, C. P. Pohlman, B. et al. (2008) Prognostic significance of VEGF, VEGF receptors, and microvessel density in diffuse large B cell lymphoma treated with anthracycline-based chemotherapy. Lab Invest, 88, pp. 38-47.
-
(2008)
Lab Invest
, vol.88
, pp. 38-47
-
-
Gratzinger, D.1
Zhao, S.2
Tibshirani, R.J.3
Hsi, E.D.4
Hans, C.P.5
Pohlman, B.6
-
27
-
-
33947678733
-
Angiogenesis in non-Hodgkin's lymphoma: Clinico-pathological correlations and prognostic significance in specific subtypes
-
Jørgensen, J. M., Sørensen, F. B., Bendix, K., Nielsen, J. L., Olsen, M. L. Funder, A. M. et al. (2007) Angiogenesis in non-Hodgkin's lymphoma: Clinico-pathological correlations and prognostic significance in specific subtypes. Leuk Lymphoma, 48, pp. 584-595.
-
(2007)
Leuk Lymphoma
, vol.48
, pp. 584-595
-
-
Jørgensen, J.M.1
Sørensen, F.B.2
Bendix, K.3
Nielsen, J.L.4
Olsen, M.L.5
Funder, A.M.6
-
28
-
-
0033767663
-
Microvessel density in chemosensitive and chemoresistant diffuse large B-cell lymphomas
-
Bairey, O., Zimra, Y., Kaganovsky, E., Shaklai, M., Okon, E. and Rabizadeh, E. (2000) Microvessel density in chemosensitive and chemoresistant diffuse large B-cell lymphomas. Med Oncol, 17, pp. 314-318.
-
(2000)
Med Oncol
, vol.17
, pp. 314-318
-
-
Bairey, O.1
Zimra, Y.2
Kaganovsky, E.3
Shaklai, M.4
Okon, E.5
Rabizadeh, E.6
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