Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 282, Issue 1 26-1, 2002, Pages

  Storme, Laurent ^a,b   Parker, Thomas A ^a,b   Kinsella, John P ^a,b   Rairigh, Robyn L ^a,b   Abman, Steven H ^a,b,c  

^a LILLE UNIVERSITY HOSPITAL   (France)

^b Children's Hospital Colorado   (United States)

^c CHILDREN S HOSPITAL   (United States)

Author keywords

Calcium channels; Myogenic response; Nitric oxide; Persistent pulmonary hypertension of the newborn; Pulmonary circulation; Smooth muscle

Indexed keywords

NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY COMPRESSION; ARTICLE; BLOOD VESSEL TONE; CONTROLLED STUDY; DUCTUS ARTERIOSUS; FETUS; FETUS LUNG; LAMB; LUNG BLOOD FLOW; LUNG VASCULAR RESISTANCE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PULMONARY HYPERTENSION; VASODILATATION;

EID: 0036086026     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2002.282.1.l56     Document Type: Article

References (43)

1. Acute effects of partial compression of ductus arteriosus on fetal pulmonary circulation
2. Sustained fetal pulmonary vasodilation during prolonged infusion of atrial natriuretic factor and 8-bromo-guansosine monophosphate
3. Adaptation of fetal pulmonary blood flow to local infusion of tolazoline
4. Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth
5. Physiologic roles of NO in the perinatal pulmonary circulation
6. Failure of postnatal adaptation of the pulmonary circulation after chronic intrauterine pulmonary hypertension in fetal lambs
7. Time-dependent response of fetal pulmonary blood flow to an increase in fetal oxygen tension
8. On the local reactions of the arterial wall to changes of internal pressure
9. Myogenic response in large pulmonary arteries and its ontogenesis
10. Effects of birth-related stimuli on L-arginine-dependant pulmonary vasodilation in ovine fetus
11. Transduction mechanisms involved in the regulation of myogenic activity
12. Signaling mechanisms underlying the vascular myogenic response
13. Changes in the lungs of the newborn lamb
14. Production of 20-HETE and its role in autoregulation of cerebral blood flow
15. Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity
16. Pressure-dependent membrane depolarization in cat middle cerebral artery
17. Control of fetal and neonatal pulmonary circulation
18. Evidence for protein kinase C involvement in arteriolar myogenic reactivity
19. Calcium entry and myogenic phenomena in skeletal muscle arterioles
20. Physiologic characterization of endothelin A and B receptor activity in the ovine fetal pulmonary circulation
21. Prolonged endothelin A receptor blockade attenuates chronic intrauterine pulmonary hypertension
22. Endothelin blockade augments fetal pulmonary vasodilation
23. Regulation of vascular tone. Role of 20-HETE in the modulation of myogenic reactivity
24. Recent developments in the pathophysiology and treatment of persistent pulmonary hypertension of the newborn
25. Stretch-induced contraction in pulmonary arteries
26. Persistent pulmonary hypertension of the newborn
27. Mechanical stress initiated signal transductions in vascular smooth mucle cells
28. Effects of oxygen and exogenous L-arginine on EDRF activity in the fetal pulmonary circulation
29. Chronic pulmonary hypertension in utero impairs endothelium-dependent vasodilation
30. Cellular mechanisms involved in the vascular myogenic response
31. Ligating the ductus arteriosus before birth causes persistent pulmonary hypertension in the newborn lamb
32. Calcium channels, potassium channels, and voltage dependence of arterial smooth muscle tone
33. Fetal and neonatal pulmonary circulation
34. Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension
35. Disruption of cGMP production in pulmonary arteries isolated from fetal lambs with pulmonary hypertension
36. In vivo evidence for a myogenic response in the fetal pulmonary circulation
37. Acute pulmonary hypertension in utero impairs endothelium-dependent vasodilation
38. NO-20-HETE interaction in the regulation of K+ channel activity and vascular tone in renal arterioles
39. Increasing oxygen tension dilates fetal pulmonary circulation via endothelium-derived relaxing factor
40. Prostaglandin inhibition prevents the fall in pulmonary vascular resistance as the result of rhythmic distension of the lungs in fetal lambs
41. Chronic hypertension impairs endothelial NO synthase in the ovine fetus
42. Voltage-operated calcium channels are essential for the myogenic responsiveness of cannulated rat mesenteric small arteries
43. NO and prostaglandin interactions during hemodynamic stress in the fetal ovine pulmonary circulation