메뉴 건너뛰기




Volumn 53, Issue 6, 2008, Pages 685-697

Intratumoural heterogeneity of intestinal expression reflects environmental induction and progression-related loss of induction in undifferentiated-type gastric carcinomas

Author keywords

Cdx2; MUC2; Tissue environment; Tumour progression; Undifferentiated type gastric carcinoma

Indexed keywords

MUCIN 2; MUCIN 5AC; MUCIN 6; TRANSCRIPTION FACTOR CDX2;

EID: 57049113143     PISSN: 03090167     EISSN: 13652559     Source Type: Journal    
DOI: 10.1111/j.1365-2559.2008.03166.x     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Laurén P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta. Pathol. Microbiol. Scand. 1965 6 31 49.
    • (1965) Acta. Pathol. Microbiol. Scand. , vol.6 , pp. 31-49
    • Laurén, P.1
  • 2
    • 0001126352 scopus 로고    scopus 로고
    • Classification of gastric carcinomas
    • Carneiro F. Classification of gastric carcinomas. Curr. Diagn. Pathol. 1997 4 51 59.
    • (1997) Curr. Diagn. Pathol. , vol.4 , pp. 51-59
    • Carneiro, F.1
  • 4
    • 0027138853 scopus 로고
    • Association between expression of sialosyl-Tn antigen and intestinalization of gastric carcinomas
    • Kushima R, Jancic S, Hattori T. Association between expression of sialosyl-Tn antigen and intestinalization of gastric carcinomas. Int. J. Cancer 1993 55 904 908.
    • (1993) Int. J. Cancer , vol.55 , pp. 904-908
    • Kushima, R.1    Jancic, S.2    Hattori, T.3
  • 5
    • 9844223915 scopus 로고    scopus 로고
    • Intestinalization of gastric signet ring cell carcinomas with progression
    • Yamachika T, Inada K, Fujimitsu Y et al. Intestinalization of gastric signet ring cell carcinomas with progression. Virchows Arch. 1997 431 103 110.
    • (1997) Virchows Arch. , vol.431 , pp. 103-110
    • Yamachika, T.1    Inada, K.2    Fujimitsu, Y.3
  • 6
    • 0035144459 scopus 로고    scopus 로고
    • Time-dependent expression of intestinal phenotype in signet ring cell carcinomas of the human stomach
    • Bamba M, Sugihara H, Kushima R et al. Time-dependent expression of intestinal phenotype in signet ring cell carcinomas of the human stomach. Virchows Arch. 2001 438 49 56.
    • (2001) Virchows Arch. , vol.438 , pp. 49-56
    • Bamba, M.1    Sugihara, H.2    Kushima, R.3
  • 7
    • 32944459562 scopus 로고    scopus 로고
    • High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk
    • Maekita T, Nakazawa K, Mihara M et al. High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin. Cancer Res. 2006 12 989 995.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 989-995
    • Maekita, T.1    Nakazawa, K.2    Mihara, M.3
  • 8
    • 13444305417 scopus 로고    scopus 로고
    • Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients
    • Yuasa Y, Nagasaki H, Akiyama Y et al. Relationship between CDX2 gene methylation and dietary factors in gastric cancer patients. Carcinogenesis 2005 26 193 200.
    • (2005) Carcinogenesis , vol.26 , pp. 193-200
    • Yuasa, Y.1    Nagasaki, H.2    Akiyama, Y.3
  • 9
    • 4944240215 scopus 로고    scopus 로고
    • Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: An active role for the tumor environment in malignant tumor progression
    • Brabletz T, Spaderna S, Kolb J et al. Down-regulation of the homeodomain factor Cdx2 in colorectal cancer by collagen type I: an active role for the tumor environment in malignant tumor progression. Cancer Res. 2004 64 6973 6977.
    • (2004) Cancer Res. , vol.64 , pp. 6973-6977
    • Brabletz, T.1    Spaderna, S.2    Kolb, J.3
  • 10
    • 33947536361 scopus 로고    scopus 로고
    • The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells
    • Benahmed F, Gross I, Guenot D et al. The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells. Am. J. Pathol. 2007 170 733 744.
    • (2007) Am. J. Pathol. , vol.170 , pp. 733-744
    • Benahmed, F.1    Gross, I.2    Guenot, D.3
  • 11
    • 0037462878 scopus 로고    scopus 로고
    • Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression
    • Yamamoto H, Bai YQ, Yuasa Y. Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expression. Biochem. Biophys. Res. Commun. 2003 300 813 818.
    • (2003) Biochem. Biophys. Res. Commun. , vol.300 , pp. 813-818
    • Yamamoto, H.1    Bai, Y.Q.2    Yuasa, Y.3
  • 12
    • 4143133366 scopus 로고    scopus 로고
    • Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia
    • Faller G, Dimmler A, Rau T et al. Evidence for acid-induced loss of Cdx2 expression in duodenal gastric metaplasia. J. Pathol. 2004 203 904 908.
    • (2004) J. Pathol. , vol.203 , pp. 904-908
    • Faller, G.1    Dimmler, A.2    Rau, T.3
  • 13
    • 0035060772 scopus 로고    scopus 로고
    • Histologic heterogeneity and mucin phenotypic expression in early gastric cancer
    • Saito A, Shimoda T, Nakanishi Y, Ochiai A, Toda G. Histologic heterogeneity and mucin phenotypic expression in early gastric cancer. Pathol. Int. 2001 51 165 171.
    • (2001) Pathol. Int. , vol.51 , pp. 165-171
    • Saito, A.1    Shimoda, T.2    Nakanishi, Y.3    Ochiai, A.4    Toda, G.5
  • 14
    • 0242558946 scopus 로고    scopus 로고
    • Alterations of chromosomal copy number during progression of diffuse-type gastric carcinomas: Metaphase- and array-based comparative genomic hybridization analyses of multiple samples from individual tumours
    • Peng DF, Sugihara H, Mukaisho K, Tsubosa Y, Hattori T. Alterations of chromosomal copy number during progression of diffuse-type gastric carcinomas: metaphase- and array-based comparative genomic hybridization analyses of multiple samples from individual tumours. J. Pathol. 2003 201 439 450.
    • (2003) J. Pathol. , vol.201 , pp. 439-450
    • Peng, D.F.1    Sugihara, H.2    Mukaisho, K.3    Tsubosa, Y.4    Hattori, T.5
  • 15
    • 4143081638 scopus 로고    scopus 로고
    • Genetic lineage of poorly differentiated gastric carcinoma with a tubular component analysed by comparative genomic hybridization
    • Peng DF, Sugihara H, Mukaisho K, Ling ZQ, Hattori T. Genetic lineage of poorly differentiated gastric carcinoma with a tubular component analysed by comparative genomic hybridization. J. Pathol. 2004 203 884 895.
    • (2004) J. Pathol. , vol.203 , pp. 884-895
    • Peng, D.F.1    Sugihara, H.2    Mukaisho, K.3    Ling, Z.Q.4    Hattori, T.5
  • 16
    • 33745432825 scopus 로고    scopus 로고
    • How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: Analyses of intratumoral heterogeneity in deletion and mutation of TP53
    • Yoshimura A, Sugihara H, Ling ZQ et al. How wild-type TP53 is inactivated in undifferentiated-type gastric carcinomas: analyses of intratumoral heterogeneity in deletion and mutation of TP53. Pathobiology 2006 73 40 49.
    • (2006) Pathobiology , vol.73 , pp. 40-49
    • Yoshimura, A.1    Sugihara, H.2    Ling, Z.Q.3
  • 17
    • 0025857145 scopus 로고
    • Morphology and modes of cell proliferation in earliest signet-ring-cell carcinomas induced in canine stomachs by N-ethyl-N'-nitro-N-nitrosoguanidine
    • Sugihara H, Hattori T, Imamura Y et al. Morphology and modes of cell proliferation in earliest signet-ring-cell carcinomas induced in canine stomachs by N-ethyl-N'-nitro-N-nitrosoguanidine. J. Cancer Res. Clin. Oncol. 1991 117 197 204.
    • (1991) J. Cancer Res. Clin. Oncol. , vol.117 , pp. 197-204
    • Sugihara, H.1    Hattori, T.2    Imamura, Y.3
  • 18
    • 0023279562 scopus 로고
    • Cell proliferation and differentiation in intramucosal and advanced signet ring cell carcinomas of the human stomach
    • Sugihara H, Hattori T, Fukuda M, Fujita S. Cell proliferation and differentiation in intramucosal and advanced signet ring cell carcinomas of the human stomach. Virchows Arch. A Pathol. Anat. Histopathol. 1987 411 117 127.
    • (1987) Virchows Arch. a Pathol. Anat. Histopathol. , vol.411 , pp. 117-127
    • Sugihara, H.1    Hattori, T.2    Fukuda, M.3    Fujita, S.4
  • 19
    • 0034019828 scopus 로고    scopus 로고
    • Gastric carcinoma exhibits distinct types of cell differentiation: An immunohistochemical study of trefoil peptides (TFF1 and TFF2) and mucins (MUC1, MUC2, MUC5AC, and MUC6)
    • Machado JC, Nogueira AM, Carneiro F, Reis CA, Sobrinho-Simões M. Gastric carcinoma exhibits distinct types of cell differentiation: an immunohistochemical study of trefoil peptides (TFF1 and TFF2) and mucins (MUC1, MUC2, MUC5AC, and MUC6). J. Pathol. 2000 190 437 443.
    • (2000) J. Pathol. , vol.190 , pp. 437-443
    • MacHado, J.C.1    Nogueira, A.M.2    Carneiro, F.3    Reis, C.A.4    Sobrinho-Simões, M.5
  • 20
    • 13844281020 scopus 로고    scopus 로고
    • Dynamic alteration of the E-cadherin/catenin complex during cell differentiation and invasion of undifferentiated-type gastric carcinomas
    • Nakamura E, Sugihara H, Bamba M, Hattori T. Dynamic alteration of the E-cadherin/catenin complex during cell differentiation and invasion of undifferentiated-type gastric carcinomas. J. Pathol. 2005 205 349 358.
    • (2005) J. Pathol. , vol.205 , pp. 349-358
    • Nakamura, E.1    Sugihara, H.2    Bamba, M.3    Hattori, T.4
  • 21
    • 0346847596 scopus 로고    scopus 로고
    • Expression of Cdx2 and the phenotype of advanced gastric cancers: Relationship with prognosis
    • Mizoshita T, Tsukamoto T, Nakanishi H et al. Expression of Cdx2 and the phenotype of advanced gastric cancers: relationship with prognosis. J. Cancer Res. Clin. Oncol. 2003 129 727 734.
    • (2003) J. Cancer Res. Clin. Oncol. , vol.129 , pp. 727-734
    • Mizoshita, T.1    Tsukamoto, T.2    Nakanishi, H.3
  • 22
    • 36248939194 scopus 로고    scopus 로고
    • CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer
    • Liu Q, Teh M, Ito K, Shah N, Ito Y, Yeoh KG. CDX2 expression is progressively decreased in human gastric intestinal metaplasia, dysplasia and cancer. Mod. Pathol. 2007 20 1286 1297.
    • (2007) Mod. Pathol. , vol.20 , pp. 1286-1297
    • Liu, Q.1    Teh, M.2    Ito, K.3    Shah, N.4    Ito, Y.5    Yeoh, K.G.6
  • 23
    • 4744338918 scopus 로고    scopus 로고
    • Three independent genetic profiles based on mucin expression in early differentiated-type gastric cancers - A new concept of genetic carcinogenesis of early differentiated-type adenocarcinomas
    • Sugai T, Habano W, Uesugi N et al. Three independent genetic profiles based on mucin expression in early differentiated-type gastric cancers - a new concept of genetic carcinogenesis of early differentiated-type adenocarcinomas. Mod. Pathol. 2004 17 1223 1234.
    • (2004) Mod. Pathol. , vol.17 , pp. 1223-1234
    • Sugai, T.1    Habano, W.2    Uesugi, N.3
  • 24
    • 26444567734 scopus 로고    scopus 로고
    • Loss of phenotypic expression is related to tumour progression in early gastric differentiated adenocarcinoma
    • Nakamura T, Yao T, Kabashima A, Nishiyama K, Maehara Y, Tsuneyoshi M. Loss of phenotypic expression is related to tumour progression in early gastric differentiated adenocarcinoma. Histopathology 2005 47 357 367.
    • (2005) Histopathology , vol.47 , pp. 357-367
    • Nakamura, T.1    Yao, T.2    Kabashima, A.3    Nishiyama, K.4    Maehara, Y.5    Tsuneyoshi, M.6
  • 25
    • 0033917229 scopus 로고    scopus 로고
    • Cellular phenotypes of differentiated-type adenocarcinomas and precancerous lesions of the stomach are dependent on the genetic pathways
    • Endoh Y, Sakata K, Tamura G et al. Cellular phenotypes of differentiated-type adenocarcinomas and precancerous lesions of the stomach are dependent on the genetic pathways. J. Pathol. 2001 191 257 263.
    • (2001) J. Pathol. , vol.191 , pp. 257-263
    • Endoh, Y.1    Sakata, K.2    Tamura, G.3
  • 26
    • 33751292686 scopus 로고    scopus 로고
    • Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: Clinicopathologic significance and genetic background
    • Tajima Y, Yamazaki K, Makino R et al. Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background. Clin. Cancer Res. 2006 12 6469 6479.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 6469-6479
    • Tajima, Y.1    Yamazaki, K.2    Makino, R.3
  • 27
    • 0031919583 scopus 로고    scopus 로고
    • Correlation of the immunohistochemical reactivity of mucin peptide cores MUC1 and MUC2 with the histopathological subtype and prognosis of gastric carcinomas
    • Baldus SE, Zirbes TK, Engel S et al. Correlation of the immunohistochemical reactivity of mucin peptide cores MUC1 and MUC2 with the histopathological subtype and prognosis of gastric carcinomas. Int. J. Cancer 1998 79 133 138.
    • (1998) Int. J. Cancer , vol.79 , pp. 133-138
    • Baldus, S.E.1    Zirbes, T.K.2    Engel, S.3
  • 28
    • 0031756619 scopus 로고    scopus 로고
    • Expression of MUC1 and MUC2 mucins in gastric carcinomas: Its relationship with the prognosis of the patients
    • Utsunomiya T, Yonezawa S, Sakamoto H et al. Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients. Clin. Cancer Res. 1998 4 2605 2614.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 2605-2614
    • Utsunomiya, T.1    Yonezawa, S.2    Sakamoto, H.3
  • 29
    • 24344508123 scopus 로고    scopus 로고
    • Expression of Cdx2 and hepatocyte antigen in gastric carcinoma: Correlation with histologic type and implications for prognosis
    • Fan Z, Li J, Dong B, Huang X. Expression of Cdx2 and hepatocyte antigen in gastric carcinoma: correlation with histologic type and implications for prognosis. Clin. Cancer Res. 2005 11 6162 6170.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 6162-6170
    • Fan, Z.1    Li, J.2    Dong, B.3    Huang, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.