Uptake and release of budesonide from mucoadhesive, pH-sensitive copolymers and their application to nasal delivery

Journal of Controlled Release

Volumn 61, Issue 3, 1999, Pages 329-335

  Nakamura, Kouji ^a   Maitani, Yoshie ^a   Lowman, Anthony M ^b   Takayama, Kozo ^a   Peppas, Nicholas A ^c   Nagai, T ^a  

^a HOSHI UNIVERSITY   (Japan)

^b DREXEL UNIVERSITY   (United States)

^c Purdue University   (United States)

Author keywords

Budesonide; Mucoadhesive copolymers; Nasal administration; pH sensitive copolymers

Indexed keywords

BUDESONIDE; COPOLYMER; NANOPARTICLE;

ANIMAL EXPERIMENT; ARTICLE; BIOAVAILABILITY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG UPTAKE; INTRANASAL DRUG ADMINISTRATION; MALE; NONHUMAN; PH; PRIORITY JOURNAL; RABBIT;

ADHESIVENESS; ADMINISTRATION, INTRANASAL; ANIMALS; BIOCOMPATIBLE MATERIALS; BRONCHODILATOR AGENTS; BUDESONIDE; GELS; HYDROGEN-ION CONCENTRATION; MALE; NASAL MUCOSA; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS; RABBITS; SOLUTIONS;

EID: 0032848448     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(99)00150-9     Document Type: Article

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