Long-Range Enhancer Differentially Regulated by c-Jun and JunD Controls Peptidylarginine Deiminase-3 Gene in Keratinocytes

Journal of Molecular Biology

Volumn 384, Issue 5, 2008, Pages 1048-1057

  Adoue, Véronique ^a   Chavanas, Stéphane ^a   Coudane, Fanny ^a   Méchin, Marie Claire ^a   Caubet, Cécile ^a   Ying, Shibo ^b   Dong, Sijun ^b   Duplan, Hélène ^c   Charveron, Marie ^c   Takahara, Hidenari ^b   Serre, Guy ^a   Simon, Michel ^a  

^a UNIVERSITÉ PAUL SABATIER   (France)

^b IBARAKI UNIVERSITY   (Japan)

^c INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

AP 1; epidermis; gene expression; peptidylarginine deiminases; transcription

Indexed keywords

PROTEIN ARGININE DEIMINASE; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR JUND;

ARTICLE; CELL DIFFERENTIATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DELETION MUTANT; ENZYME ACTIVITY; GENE CONTROL; GENE IDENTIFICATION; GENE LOCUS; HUMAN; HUMAN CELL; KERATINOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 56949088417     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.10.019     Document Type: Article

References (50)

1. Howard M.L., and Davidson E.H. cis-Regulatory control circuits in development. Dev. Biol. 271 (2004) 109-118
2. Hatton R.D., Harrington L.E., Luther R.J., Wakefield T., Janowski K.M., Oliver J.R., et al. A distal conserved sequence element controls Ifng gene expression by T cells and NK cells. Immunity 25 (2006) 717-729
3. Antonini D., Rossi B., Han R., Minichiello A., Di Palma T., Corrado M., et al. An autoregulatory loop directs the tissue-specific expression of p63 through a long-range evolutionarily conserved enhancer. Mol. Cell. Biol. 26 (2006) 3308-3318
4. Li Q., Peterson K.R., Fang X., and Stamatoyannopoulos G. Locus control regions. Blood 100 (2002) 3077-3086
5. Martin N., Patel S., and Segre J.A. Long-range comparison of human and mouse Sprr loci to identify conserved noncoding sequences involved in coordinate regulation. Genome Res. 14 (2004) 2430-2438
6. Pennacchio L.A., Ahituv N., Moses A.M., Prabhakar S., Nobrega M.A., Shoukry M., et al. In vivo enhancer analysis of human conserved non-coding sequences. Nature 444 (2006) 499-502
7. Guerrin M., Ishigami A., Mechin M.C., Nachat R., Valmary S., Sebbag M., et al. cDNA cloning, gene organization and expression analysis of human peptidylarginine deiminase type I. Biochem. J. 370 (2003) 167-174
8. Chavanas S., Mechin M.C., Takahara H., Kawada A., Nachat R., Serre G., and Simon M. Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6. Gene 330 (2004) 19-27
9. Moscarello M.A., Pritzker L., Mastronardi F.G., and Wood D.D. Peptidylarginine deiminase: a candidate factor in demyelinating disease. J. Neurochem. 81 (2002) 335-343
10. Suzuki A., Yamada R., Chang X., Tokuhiro S., Sawada T., Suzuki M., et al. Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis. Nat. Genet. 34 (2003) 395-402
11. Hagiwara T., Nakashima K., Hirano H., Senshu T., and Yamada M. Deimination of arginine residues in nucleophosmin/B23 and histones in HL-60 granulocytes. Biochem. Biophys. Res. Commun. 290 (2002) 979-983
12. Wang Y., Wysocka J., Sayegh J., Lee Y.H., Perlin J.R., Leonelli L., et al. Human PAD4 regulates histone arginine methylation levels via demethylimination. Science 306 (2004) 279-283
13. Ishida-Yamamoto A., McGrath J.A., Judge M.R., Leigh I.M., Lane E.B., and Eady R.A. Selective involvement of keratins K1 and K10 in the cytoskeletal abnormality of epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma). J. Invest. Dermatol. 99 (1992) 19-26
14. Ishida-Yamamoto A., Senshu T., Takahashi H., Akiyama K., Nomura K., and Iizuka H. Decreased deiminated keratin K1 in psoriatic hyperproliferative epidermis. J. Invest. Dermatol. 114 (2000) 701-705
15. Segre J.A. Epidermal barrier formation and recovery in skin disorders. J. Clin. Invest. 116 (2006) 1150-1158
16. Fuchs E. Skin stem cells: rising to the surface. J. Cell Biol. 180 (2008) 273-284
17. Nachat R., Mechin M.C., Takahara H., Chavanas S., Charveron M., Serre G., and Simon M. Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin. J. Invest. Dermatol. 124 (2005) 384-393
18. Dong S., Kojima T., Shiraiwa M., Mechin M.C., Chavanas S., Serre G., et al. Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors. J. Invest. Dermatol. 124 (2005) 1026-1033
19. Dong S., Kanno T., Yamaki A., Kojima T., Shiraiwa M., Kawada A., et al. NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes. Biochem. J. 397 (2006) 449-459
20. Dong S., Zhang Z., and Takahara H. Estrogen-enhanced peptidylarginine deiminase type IV gene (PADI4) expression in MCF-7 cells is mediated by estrogen receptor-alpha-promoted transfactors activator protein-1, nuclear factor-Y, and Sp1. Mol. Endocrinol. 21 (2007) 1617-1629
21. Dong S., Ying S., Kojima T., Shiraiwa M., Kawada A., Mechin M.C., et al. Crucial Roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes. J. Invest. Dermatol. 128 (2008) 549-557
22. Boyce S.T., and Ham R.G. Calcium-regulated differentiation of normal human epidermal keratinocytes in chemically defined clonal culture and serum-free serial culture. J. Invest. Dermatol. 81 (1983) 33s-40s
23. McArthur M., Gerum S., and Stamatoyannopoulos G. Quantification of DNaseI-sensitivity by real-time PCR: quantitative analysis of DNaseI-hypersensitivity of the mouse beta-globin LCR. J. Mol. Biol. 313 (2001) 27-34
24. Angel P., Szabowski A., and Schorpp-Kistner M. Function and regulation of AP-1 subunits in skin physiology and pathology. Oncogene 20 (2001) 2413-2423
25. Mehic D., Bakiri L., Ghannadan M., Wagner E.F., and Tschachler E. Fos and jun proteins are specifically expressed during differentiation of human keratinocytes. J. Invest. Dermatol. 124 (2005) 212-220
26. Brand A.H., Breeden L., Abraham J., Sternglanz R., and Nasmyth K. Characterization of a "silencer" in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41 (1985) 41-48
27. Makino R., Akiyama K., Yasuda J., Mashiyama S., Honda S., Sekiya T., and Hayashi K. Cloning and characterization of a c-myc intron binding protein (MIBP1). Nucleic Acids Res. 22 (1994) 5679-5685
28. Moore B.B., Cao Z.A., McRae T.L., Woo C.H., Conley S., and Jones P.P. The invariant chain gene intronic enhancer shows homology to class II promoter elements. J. Immunol. 161 (1998) 1844-1852
29. Blake M., Niklinski J., and Zajac-Kaye M. Interactions of the transcription factors MIBP1 and RFX1 with the EP element of the hepatitis B virus enhancer. J. Virol. 70 (1996) 6060-6066
30. Toulza E., Mattiuzzo N.R., Galliano M.F., Jonca N., Dossat C., Jacob D., et al. Large-scale identification of human genes implicated in epidermal barrier function. Genome Biol. 8 (2007) R107
31. Katan Y., Agami R., and Shaul Y. The transcriptional activation and repression domains of RFX1, a context-dependent regulator, can mutually neutralize their activities. Nucleic Acids Res. 25 (1997) 3621-3628
32. Fukuda S., Yamasaki Y., Iwaki T., Kawasaki H., Akieda S., Fukuchi N., et al. Characterization of the biological functions of a transcription factor, c-myc intron binding protein 1 (MIBP1). J. Biochem. 131 (2002) 349-357
33. Crish J.F., Zaim T.M., and Eckert R.L. The distal regulatory region of the human involucrin promoter is required for expression in epidermis. J. Biol. Chem. 273 (1998) 30460-30465
34. Jang S.I., and Steinert P.M. Loricrin expression in cultured human keratinocytes is controlled by a complex interplay between transcription factors of the Sp1, CREB, AP1, and AP2 families. J. Biol. Chem. 277 (2002) 42268-42279
35. Park S., Hahm E.R., Lee D.K., and Yang C.H. Inhibition of AP-1 transcription activator induces myc-dependent apoptosis in HL60 cells. J. Cell. Biochem. 91 (2004) 973-986
36. Mechta-Grigoriou F., Gerald D., and Yaniv M. The mammalian Jun proteins: redundancy and specificity. Oncogene 20 (2001) 2378-2389
37. Patel A.R., and Wang J.Y. Polyamine depletion is associated with an increase in JunD/AP-1 activity in small intestinal crypt cells. Am. J. Physiol. 276 (1999) G441-G450
38. Pfarr C.M., Mechta F., Spyrou G., Lallemand D., Carillo S., and Yaniv M. Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras. Cell 76 (1994) 747-760
39. Bossy-Wetzel E., Bravo R., and Hanahan D. Transcription factors junB and c-Jun are selectively up-regulated and functionally implicated in fibrosarcoma development. Genes Dev. 6 (1992) 2340-2351
40. Molete J.M., Petrykowska H., Bouhassira E.E., Feng Y.Q., Miller W., and Hardison R.C. Sequences flanking hypersensitive sites of the beta-globin locus control region are required for synergistic enhancement. Mol. Cell. Biol. 21 (2001) 2969-2980
41. Feng Y.Q., Warin R., Li T., Olivier E., Besse A., Lobell A., et al. The human beta-globin locus control region can silence as well as activate gene expression. Mol. Cell. Biol. 25 (2005) 3864-3874
42. Banks E.B., Crish J.F., Welter J.F., and Eckert R.L. Characterization of human involucrin promoter distal regulatory region transcriptional activator elements-a role for Sp1 and AP1 binding sites. Biochem. J. 331 Pt 1 (1998) 61-68
43. Chinenov Y., and Kerppola T.K. Close encounters of many kinds: Fos-Jun interactions that mediate transcription regulatory specificity. Oncogene 20 (2001) 2438-2452
44. Maijgren S., Sur I., Nilsson M., and Toftgard R. Involvement of RFX proteins in transcriptional activation from a Ras-responsive enhancer element. Arch. Dermatol. Res. 295 (2004) 482-489
45. Andersson G., and Peterlin B.M. NF-X2 that binds to the DRA X2-box is activator protein 1. Expression cloning of c-Jun. J. Immunol. 145 (1990) 3456-3462
46. Ohtsuki S., Levine M., and Cai H.N. Different core promoters possess distinct regulatory activities in the Drosophila embryo. Genes Dev. 12 (1998) 547-556
47. Bertolino E., and Singh H. POU/TBP cooperativity: a mechanism for enhancer action from a distance. Mol. Cell 10 (2002) 397-407
48. Steidl U., Steidl C., Ebralidze A., Chapuy B., Han H.J., Will B., et al. A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia. J. Clin. Invest. 117 (2007) 2611-2620
49. Yang R., Frank B., Hemminki K., Bartram C.R., Wappenschmidt B., Sutter C., et al. SNPs in ultraconserved elements and familial breast cancer risk. Carcinogenesis 29 (2008) 351-355
50. Soutoglou E., Viollet B., Vaxillaire M., Yaniv M., Pontoglio M., and Talianidis I. Transcription factor-dependent regulation of CBP and P/CAF histone acetyltransferase activity. EMBO J. 20 (2001) 1984-1992