Newer GABA derivatives for the treatment of epilepsy including febrile seizures: A bioisosteric approach

European Journal of Medicinal Chemistry

Volumn 43, Issue 12, 2008, Pages 2650-2655

  Ragavendran, Jegadeesan Vaigunda ^a   Sriram, Dharmarajan ^a   Kotapati, Srikanth ^a   Stables, James ^b   Yogeeswari, Perumal ^a  

^a BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE   (India)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Anticonvulsants; Febrile seizures; GABA; Pentylenetetrazole; Picrotoxin; Strychnine; Thiosemicarbazones

Indexed keywords

4 (HYDRAZINOCARBOTHIOAMIDO)BUTANOIC ACID; 4 [2 (DIPHENYLMETHYLENE)HYDRAZINOCARBOTHIOAMIDO]BUTANOIC ACID; 4 AMINOBUTYRIC ACID DERIVATIVE; THIOSEMICARBAZONE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; DISEASE MODEL; DRUG EFFECT; DRUG EFFICACY; DRUG STRUCTURE; EPILEPSY; FEBRILE CONVULSION; NONHUMAN; PROTECTION; RAT; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ANIMALS; ANTICONVULSANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; EPILEPSY; FEVER; GAMMA-AMINOBUTYRIC ACID; MICE; MOLECULAR STRUCTURE; RATS; RATS, WISTAR; SEIZURES, FEBRILE;

EID: 56949083395     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.036     Document Type: Article

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