The inhibitory effect of diphenyltin on gap junctional intercellular communication in HEK-293 cells is reduced by thioredoxin reductase 1

Toxicology Letters

Volumn 183, Issue 1-3, 2008, Pages 45-51

  Sroka, Jolanta ^a   Czyz, Jarosław ^a   Wojewoda, Marta ^a   Madeja, Zbigniew ^a  

^a JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

Diphenyltin; Gap junctional intercellular communication; Protein kinase C; Redox regulation; Thioredoxin reductase

Indexed keywords

CONNEXIN 43; DIPHENYLTIN; ORGANOTIN COMPOUND; PROTEIN KINASE C DELTA; SERINE; THIOREDOXIN REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CELL COMMUNICATION; CELL STRAIN HEK293; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; GAP JUNCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

BLOTTING, WESTERN; CELL COMMUNICATION; CELL LINE; CELL SURVIVAL; CONNEXIN 43; FLUORESCENT ANTIBODY TECHNIQUE; GAP JUNCTIONS; HUMANS; ORGANOTIN COMPOUNDS; PHOSPHORYLATION; PROTEIN KINASE C-DELTA; RNA, SMALL INTERFERING; SERINE; THIOREDOXIN REDUCTASE 1; TIME FACTORS; TRANSFECTION;

ANIMALIA;

EID: 56749180723     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2008.09.012     Document Type: Article

References (61)

1. Appel K.E. Organotin compounds: toxicokinetic aspects. Drug Metab. Rev. 36 (2004) 763-786
2. Bao X., Altenberg G.A., and Reuss L. Mechanism of regulation of the gap junction protein connexin 43 by protein kinase C-mediated phosphorylation. Am. J. Physiol. Cell Physiol. 286 (2004) 647-654
3. Costa L.G. Signal transduction in environmental neurotoxicity. Annu. Rev. Pharmacol. Toxicol. 38 (1998) 21-43
4. Cruciani V., Husøy T., and Mikalsen S.O. Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication. Exp. Cell Res. 268 (2001) 150-161
5. Cruciani V., and Mikalsen S.O. Connexins, gap junctional intercellular communication and kinases. Biol. Cell 94 (2002) 433-443
6. Czyz J. The stage-specific function of gap junctions during tumourigenesis. Cell. Mol. Biol. Lett. 13 (2008) 92-102
7. Dagli M.L., and Hernandez-Blazquez F.J. Roles of gap junctions and connexins in non-neoplastic pathological processes in which cell proliferation is involved. J. Membr. Biol. 218 (2007) 79-91
8. Dang X., Jeyaraman M., and Kardami E. Regulation of connexin-43-mediated growth inhibition by a phosphorylatable amino-acid is independent of gap junction-forming ability. Mol. Cell Biochem. 289 (2006) 201-217
9. Doble B.W., Dang X., Ping P., Fandrich R.R., Nickel B.E., Jin Y., Cattini P.A., and Kardami E. Phosphorylation of serine 262 in the gap junction protein connexin-43 regulates DNA synthesis in cell-cell contact forming cardiomyocytes. J. Cell Sci. 117 (2004) 507-514
10. Domenicotti C., Marengo B., Verzola D., Garibotto G., Traverso N., Patriarca S., Maloberti G., Cottalasso D., Poli G., Passalacqua M., Melloni E., Pronzato M.A., and Marinari U.M. Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. Free Radic. Biol. Med. 1 (2003) 504-516
11. (i) and mitochondrial activity, causing oxidative stress and activation of caspases in rat thymocytes. Toxicol. Appl. Pharmacol. 169 (2000) 185-190
12. Goodenough D.A., and Revel J.P. The permeability of isolated and in situ mouse hepatic gap junctions studied with enzymatic tracers. J. Cell Biol. 50 (1971) 81-91
13. Gopalakrishna R., and Jaken S. Protein kinase C signaling and oxidative stress. Free Radic. Biol. Med. 28 (2000) 1349-1361
14. Gopalakrishna R., and Gundimeda U. Protein kinase C as a molecular target for cancer prevention by selenocompounds. Nutr. Cancer 40 (2001) 55-63
15. Gray B.H., Porvaznik M., Flemming C., and Lee L.H. Organotin induced hemolysis, shape transformation and intramembranous aggregates in human erythrocytes. Cell Biol. Toxicol. 3 (1987) 23-38
16. Gunasekar P.G., Mickova V., Kotyzova D., Li L., Borowitz J.L., Eybl V., and Isom G.E. Role of astrocytes in trimethyltin neurotoxicity. J. Biochem. Mol. Toxicol. 15 (2001) 256-262
17. Holmgren A. Antioxidant function of thioredoxin and glutaredoxin systems. Antioxid. Redox Signal. 2 (2000) 811-820
18. Husøy T., Cruciani V., Sanner T., and Mikalsen S.O. Phosphorylation of connexin43 and inhibition of gap junctional communication in 12-O-tetradecanoylphorbol-13-acetate-exposed R6 fibroblasts: minor role of protein kinase C beta I and mu. Carcinogenesis 22 (2001) 221-231
19. Jiang J.X., and Gu S. Gap junction- and hemichannel-independent actions of connexins. Biochim. Biophys. Acta 1711 (2005) 208-214
20. Kannan K., Tanabe S., and Tatsukawa R. Phenyltin residues in horseshoe crabs Tachypleus tridentatus from Japanese coasta waters. Chemosphere 30 (1995) 925-932
21. Keller H.U., Hunziker I.P., Sordat B., Niggli V., and Sroka J. Protein kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells. Int. J. Cancer 88 (2000) 195-203
22. Kishta O., Adeeko A., Li D., Luu T., Brawer J.R., Morales C., Hermo L., Robaire B., Hales B.F., Barthelemy J., Cyr D.G., and Trasler J.M. In utero exposure to tributyltin chloride differentially alters male and female fetal gonad morphology and gene expression profiles in the Sprague-Dawley rat. Reprod. Toxicol. 23 (2007) 1-11
23. Kleszczyńska H., Hładyszowski J., Pruchnik H., and Przestalski S. Erythrocyte hemolysis by organic tin and lead compounds. Z. Naturforsch. 52c (1997) 65-69
24. 2. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 11233-11237
25. Korichneva I., Hoyos B., Chua R., Levi E., and Hammerling U. Zinc release from protein kinase C as the common event during activation by lipid second messenger or reactive oxygen. J. Biol. Chem. 277 (2002) 44327-44331
26. Lampe P.D., and Lau A.F. The effects of connexin phosphorylation on gap junctional communication. Int. J. Biochem. Cell Biol. 36 (2004) 1171-1186
27. Laurent T.C., Moore E.C., and Reichard P. Enzymatic synthesis of deoxyribonucleotides. iv. isolation and characterization of thioredoxin, the hydrogen donor from Escherichia coli b. J. Biol. Chem. 239 (1964) 3436-3444
28. 2. J. Biol. Chem. 277 (2002) 20336-20342
29. Lee C.C., Wang T., Hsieh C.Y., and Tien C.J. Organotin contamination in fishes with different living patterns and its implications for human health risk in Taiwan. Environ. Pollut. 137 (2005) 198-208
30. Lin J.L., and Hsueh S. Acute nephropathy of organotin compounds. Am. J. Nephrol. 13 (1993) 124-128
31. Loch-Caruso R., Corcos I.A., and Trosko J.E. Inhibition of metabolic coupling by metals. J. Toxicol. Environ. Health 32 (1991) 33-48
32. Loewenstein W.R. Junctional intercellular communication and the control of growth. Biochim. Biophys. Acta 560 (1979) 1-65
33. Madeja Z., Sroka J., Nyström C., Björkhem-Bergman L., Nordman T., Damdimopoulos A., Nalvarte I., Eriksson L.C., Spyrou G., Olsson J.M., and Björnstedt M. The role of thioredoxin reductase activity in selenium-induced cytotoxicity. Biochem. Pharmacol. 69 (2005) 1765-1772
34. Miekus K., Czernik M., Sroka J., Czyz J., and Madeja Z. Contact stimulation of prostate cancer cell migration: the role of gap junctional coupling and migration stimulated by heterotypic cell-to-cell contacts in determination of the metastatic phenotype of Dunning rat prostate cancer cells. Biol. Cell 97 (2005) 893-903
35. Murray A.W., and Fitzgerald D.J. Tumor promoters inhibit metabolic cooperation in cocultures of epidermal and 3T3 cells. Biochem. Biophys. Res. Commun. 91 (1979) 395-401
36. Nalvarte I., Damdimopoulos A.E., Nyström C., Nordman T., Miranda-Vizuete A., Olsson J.M., Eriksson L., Björnstedt M., Arnér E.S., and Spyrou G. Overexpression of enzymatically active human cytosolic and mitochondrial thioredoxin reductase in HEK-293 cells. Effect on cell growth and differentiation. J. Biol. Chem. 279 (2004) 54510-54517
37. Nielsen J.B., and Strand J. Butyltin compounds in human liver. Environ. Res. 88 (2002) 129-133
38. Opacka J., and Sparrow S. Nephrotoxic effect of trimethyltin in rats. Toxicol. Lett. 7 (1985) 97-102
39. Pavlakovic G., Kane M.D., Eyer C.L., Kanthasamy A., and Isom G.E. Activation of protein kinase C by trimethyltin: relevance to neurotoxicity. J. Neurochem. 65 (1995) 2338-2343
40. Peracchia C. Chemical gating of gap junction channels; roles of calcium, pH and calmodulin. Biochim. Biophys. Acta 1662 (2004) 61-80
41. Retamal M.A., Schalper K.A., Shoji K.F., Orellana J.A., Bennett M.V., and Sáez J.C. Possible involvement of different connexin43 domains in plasma membrane permeabilization induced by ischemia-reperfusion. J. Membr. Biol. 218 (2007) 49-63
42. Rhee S.G., Kang S.W., Jeong W., Chang T.S., Yang K.S., and Woo H.A. Intracellular messenger function of hydrogen peroxide and its regulation by peroxiredoxins. Curr. Opin. Cell Biol. 17 (2005) 183-189
43. Richards T.S., Dunn C.A., Carter W.G., Usui M.L., Olerud J.E., and Lampe P.D. Protein kinase C spatially and temporally regulates gap junctional communication during human wound repair via phosphorylation of connexin43 on serine368. J. Cell Biol. 167 (2004) 555-562
44. Rivedal E., and Leithe E. Connexin43 synthesis, phosphorylation, and degradation in regulation of transient inhibition of gap junction intercellular communication by the phorbol ester TPA in rat liver epithelial cells. Exp. Cell Res. 302 (2005) 143-152
45. Saitoh M., Nishitoh H., Fujii M., Takeda K., Tobiume K., Sawada Y., Kawabata M., Miyazono K., and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J. 17 (1998) 2596-2606
46. i in bone cells. Calcif. Tissue Int. 63 (1998) 134-139
47. Söhl G., and Willecke K. Gap junctions and the connexin protein family. Cardiovasc. Res. 62 (2004) 228-232
48. Solan J.L., and Lampe P.D. Connexin phosphorylation as a regulatory event linked to gap junction channel assembly. Biochim. Biophys. Acta 1711 (2005) 154-163
49. Solan J.L., and Lampe P.D. Key connexin 43 phosphorylation events regulate the gap junction life cycle. J. Membr. Biol. 217 (2007) 35-41
50. Sroka J., Madeja Z., Galanty A., Michalik M., Przestalski S., Rakoczy L., and Korohoda W. Trimethyltin inhibits the chemotaxis of Dictyostelium discoideum amoebae. Eur. J. Protistol. 37 (2001) 313-326
51. Sroka J., Antosik A., Czyz J., Nalvarte I., Olsson J.M., Spyrou G., and Madeja Z. Overexpression of thioredoxin reductase 1 inhibits migration of HEK-293 cells. Biol. Cell 99 (2007) 77-87
52. Szydłowska H., Zaporowska E., Kuszlik-Jochym K., Korohoda W., and Branny J. Membranolytic activity of detergents as studied with cell viability tests. Folia Histochem. Cytochem. 16 (1978) 69-78
53. Tada-Oikawa S., Kato T., Kuribayashi K., Nishino K., Murata M., and Kawanishi S. Critical role of hydrogen peroxide in the differential susceptibility of Th1 and Th2 cells to tributyltin-induced apoptosis. Biochem. Pharmacol. 75 (2008) 552-561
54. Takahashi S., Mukai H., Tanabe S., Sakayama K., Miyazaki T., and Masuno H. Butyltin residues in livers of humans and wild terrestrial mammals and in plastic products. Environ. Pollut. 106 (1999) 213-218
55. Verselis V.K., Ginter C.S., and Bargiello T.A. Opposite voltage gating polarities of two closely related connexins. Nature 368 (1994) 348-351
56. Wagner C. Function of connexins in the renal circulation. Kidney Int. 73 (2008) 547-555
57. Watson J.A., Rumsby M.G., and Wolowacz R.G. Phage display identifies thioredoxin and superoxide dismutase as novel protein kinase C-interacting proteins: thioredoxin inhibits protein kinase C-mediated phosphorylation of histone. Biochem. J. 343 (1999) 301-305
58. Whalen M.M., Logananthan B.G., and Kannan K. Immunotoxicity of environmentally relevant concentrations of butyltins on human natural killer cells in vitro. Environ. Res. 81 (1999) 108-116
59. Wicki A., and Niggli V. Role of protein kinase C isoforms in locomotion of Walker 256 carcinosarcoma cells. Int. J. Cancer 8 (1999) 255-261
60. Yoshida M., Kujiraoka T., Hara M., Nakazawa H., and Sumi Y. Methylmercury inhibits gap junctional intercellular communication in primary cultures of rat proximal tubular cells. Arch. Toxicol. 72 (1998) 192-196
61. Yotti L.P., Chang C.C., and Trosko J.E. Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science 206 (1979) 1089-1091