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Volumn 201, Issue 2, 2008, Pages 289-297

Adenoviral low density lipoprotein receptor attenuates progression of atherosclerosis and decreases tissue cholesterol levels in a murine model of familial hypercholesterolemia

Author keywords

Adenoviral gene transfer; Atherosclerosis; Familial hypercholesterolemia; Low density lipoproteins; Saturated fatty acids

Indexed keywords

ADENOVIRUS VECTOR; ALPHA 1 ANTITRYPSIN; CHOLESTEROL; COCONUT OIL; HIGH DENSITY LIPOPROTEIN; INTERMEDIATE DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; VERY LOW DENSITY LIPOPROTEIN RECEPTOR;

EID: 56649109925     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2008.02.023     Document Type: Article
Times cited : (28)

References (31)
  • 1
    • 0018590304 scopus 로고
    • The LDL receptor locus and the genetics of familial hypercholesterolemia
    • Goldstein J.L., and Brown M.S. The LDL receptor locus and the genetics of familial hypercholesterolemia. Annu Rev Genet 13 (1979) 259-289
    • (1979) Annu Rev Genet , vol.13 , pp. 259-289
    • Goldstein, J.L.1    Brown, M.S.2
  • 2
    • 30744466655 scopus 로고    scopus 로고
    • Human low-density lipoprotein receptor gene and its regulation
    • Kong W.J., Liu J., and Jiang J.D. Human low-density lipoprotein receptor gene and its regulation. J Mol Med (Berl. Germany) 84 (2006) 29-36
    • (2006) J Mol Med (Berl. Germany) , vol.84 , pp. 29-36
    • Kong, W.J.1    Liu, J.2    Jiang, J.D.3
  • 3
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi S., Brown M.S., Goldstein J.L., et al. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J Clin Invest 92 (1993) 883-893
    • (1993) J Clin Invest , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3
  • 4
    • 0033827087 scopus 로고    scopus 로고
    • APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation
    • Davidson N.O., and Shelness G.S. APOLIPOPROTEIN B: mRNA editing, lipoprotein assembly, and presecretory degradation. Annu Rev Nutr 20 (2000) 169-193
    • (2000) Annu Rev Nutr , vol.20 , pp. 169-193
    • Davidson, N.O.1    Shelness, G.S.2
  • 6
    • 33750623567 scopus 로고    scopus 로고
    • Dietary fat intake and risk of coronary heart disease: the Strong Heart Study
    • Xu J., Eilat-Adar S., Loria C., et al. Dietary fat intake and risk of coronary heart disease: the Strong Heart Study. Am J Clin Nutr 84 (2006) 894-902
    • (2006) Am J Clin Nutr , vol.84 , pp. 894-902
    • Xu, J.1    Eilat-Adar, S.2    Loria, C.3
  • 7
    • 23644436341 scopus 로고    scopus 로고
    • Saturated fat-rich diet enhances selective uptake of LDL cholesteryl esters in the arterial wall
    • Seo T., Qi K., Chang C., et al. Saturated fat-rich diet enhances selective uptake of LDL cholesteryl esters in the arterial wall. J Clin Investig 115 (2005) 2214-2222
    • (2005) J Clin Investig , vol.115 , pp. 2214-2222
    • Seo, T.1    Qi, K.2    Chang, C.3
  • 8
    • 0031899062 scopus 로고    scopus 로고
    • Physical effects of cholesterol on arterial smooth muscle membranes: evidence of immiscible cholesterol domains and alterations in bilayer width during atherogenesis
    • Tulenko T.N., Chen M., Mason P.E., and Mason R.P. Physical effects of cholesterol on arterial smooth muscle membranes: evidence of immiscible cholesterol domains and alterations in bilayer width during atherogenesis. J Lipid Res 39 (1998) 947-956
    • (1998) J Lipid Res , vol.39 , pp. 947-956
    • Tulenko, T.N.1    Chen, M.2    Mason, P.E.3    Mason, R.P.4
  • 9
    • 0033758533 scopus 로고    scopus 로고
    • Lipoprotein promotes caveolin-1 and Ras translocation to caveolae: role of cholesterol in endothelial signaling
    • Zhu Y., Liao H.L., Wang N., et al. Lipoprotein promotes caveolin-1 and Ras translocation to caveolae: role of cholesterol in endothelial signaling. Arterioscler Thromb Vasc Biol 20 (2000) 2465-2470
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2465-2470
    • Zhu, Y.1    Liao, H.L.2    Wang, N.3
  • 10
    • 5444276005 scopus 로고    scopus 로고
    • Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia
    • Nomura S., Merched A., Nour E., et al. Low-density lipoprotein receptor gene therapy using helper-dependent adenovirus produces long-term protection against atherosclerosis in a mouse model of familial hypercholesterolemia. Gene Ther 11 (2004) 1540-1548
    • (2004) Gene Ther , vol.11 , pp. 1540-1548
    • Nomura, S.1    Merched, A.2    Nour, E.3
  • 11
    • 0035814955 scopus 로고    scopus 로고
    • Long-term stable correction of low-density lipoprotein receptor- deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor
    • Oka K., Pastore L., Kim I.H., et al. Long-term stable correction of low-density lipoprotein receptor- deficient mice with a helper-dependent adenoviral vector expressing the very low-density lipoprotein receptor. Circulation 103 (2001) 1274-1281
    • (2001) Circulation , vol.103 , pp. 1274-1281
    • Oka, K.1    Pastore, L.2    Kim, I.H.3
  • 12
    • 0037020162 scopus 로고    scopus 로고
    • Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA
    • Nakahara M., Fujii H., Maloney P.R., Shimizu M., and Sato R. Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA. J Biol Chem 277 (2002) 37229-37234
    • (2002) J Biol Chem , vol.277 , pp. 37229-37234
    • Nakahara, M.1    Fujii, H.2    Maloney, P.R.3    Shimizu, M.4    Sato, R.5
  • 13
    • 18744364150 scopus 로고    scopus 로고
    • Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector
    • Van Linthout S., Lusky M., Collen D., and De Geest B. Persistent hepatic expression of human apo A-I after transfer with a helper-virus independent adenoviral vector. Gene Ther 9 (2002) 1520-1528
    • (2002) Gene Ther , vol.9 , pp. 1520-1528
    • Van Linthout, S.1    Lusky, M.2    Collen, D.3    De Geest, B.4
  • 14
    • 0019486232 scopus 로고
    • A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum
    • Chapman M.J., Goldstein S., Lagrange D., and Laplaud P.M. A density gradient ultracentrifugal procedure for the isolation of the major lipoprotein classes from human serum. J Lipid Res 22 (1981) 339-358
    • (1981) J Lipid Res , vol.22 , pp. 339-358
    • Chapman, M.J.1    Goldstein, S.2    Lagrange, D.3    Laplaud, P.M.4
  • 15
    • 0021067612 scopus 로고
    • Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus
    • Camus M.C., Chapman M.J., Forgez P., and Laplaud P.M. Distribution and characterization of the serum lipoproteins and apoproteins in the mouse, Mus musculus. J Lipid Res 24 (1983) 1210-1228
    • (1983) J Lipid Res , vol.24 , pp. 1210-1228
    • Camus, M.C.1    Chapman, M.J.2    Forgez, P.3    Laplaud, P.M.4
  • 16
    • 4644247930 scopus 로고    scopus 로고
    • Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage
    • Cichon G., Willnow T., Herwig S., et al. Non-physiological overexpression of the low density lipoprotein receptor (LDLr) gene in the liver induces pathological intracellular lipid and cholesterol storage. J Gene Med 6 (2004) 166-175
    • (2004) J Gene Med , vol.6 , pp. 166-175
    • Cichon, G.1    Willnow, T.2    Herwig, S.3
  • 18
    • 0028793489 scopus 로고
    • A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia
    • Grossman M., Rader D.J., Muller D.W., et al. A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat Med 1 (1995) 1148-1154
    • (1995) Nat Med , vol.1 , pp. 1148-1154
    • Grossman, M.1    Rader, D.J.2    Muller, D.W.3
  • 19
    • 0028234357 scopus 로고
    • In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses
    • Kozarsky K.F., McKinley D.R., Austin L.L., et al. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J Biol Chem 269 (1994) 13695-13702
    • (1994) J Biol Chem , vol.269 , pp. 13695-13702
    • Kozarsky, K.F.1    McKinley, D.R.2    Austin, L.L.3
  • 20
    • 0028831356 scopus 로고
    • In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene
    • Li J., Fang B., Eisensmith R.C., et al. In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene. J Clin Invest 95 (1995) 768-773
    • (1995) J Clin Invest , vol.95 , pp. 768-773
    • Li, J.1    Fang, B.2    Eisensmith, R.C.3
  • 21
    • 0029962807 scopus 로고    scopus 로고
    • Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor
    • Kobayashi K., Oka K., Forte T., et al. Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor. J Biol Chem 271 (1996) 6852-6860
    • (1996) J Biol Chem , vol.271 , pp. 6852-6860
    • Kobayashi, K.1    Oka, K.2    Forte, T.3
  • 22
    • 0029988465 scopus 로고    scopus 로고
    • Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene
    • Kozarsky K.F., Jooss K., Donahee M., Strauss III J.F., and Wilson J.M. Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus-mediated transfer of the VLDL receptor gene. Nat Genet 13 (1996) 54-62
    • (1996) Nat Genet , vol.13 , pp. 54-62
    • Kozarsky, K.F.1    Jooss, K.2    Donahee, M.3    Strauss III, J.F.4    Wilson, J.M.5
  • 23
    • 0032945571 scopus 로고    scopus 로고
    • Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in LDL receptor-deficient mice
    • Marsh M.M., Walker V.R., Curtiss L.K., and Banka C.L. Protection against atherosclerosis by estrogen is independent of plasma cholesterol levels in LDL receptor-deficient mice. J Lipid Res 40 (1999) 893-900
    • (1999) J Lipid Res , vol.40 , pp. 893-900
    • Marsh, M.M.1    Walker, V.R.2    Curtiss, L.K.3    Banka, C.L.4
  • 24
    • 0035853043 scopus 로고    scopus 로고
    • Testosterone inhibits early atherogenesis by conversion to estradiol: critical role of aromatase
    • Nathan L., Shi W., Dinh H., et al. Testosterone inhibits early atherogenesis by conversion to estradiol: critical role of aromatase. Proc Natl Acad Sci USA 98 (2001) 3589-3593
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 3589-3593
    • Nathan, L.1    Shi, W.2    Dinh, H.3
  • 25
    • 0023870107 scopus 로고
    • Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster
    • Spady D.K., and Dietschy J.M. Interaction of dietary cholesterol and triglycerides in the regulation of hepatic low density lipoprotein transport in the hamster. J Clin Investig 81 (1988) 300-309
    • (1988) J Clin Investig , vol.81 , pp. 300-309
    • Spady, D.K.1    Dietschy, J.M.2
  • 26
    • 0029040203 scopus 로고
    • Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation
    • Abdel-Fattah G., Fernandez M.L., and McNamara D.J. Regulation of guinea pig very low density lipoprotein secretion rates by dietary fat saturation. J Lipid Res 36 (1995) 1188-1198
    • (1995) J Lipid Res , vol.36 , pp. 1188-1198
    • Abdel-Fattah, G.1    Fernandez, M.L.2    McNamara, D.J.3
  • 27
    • 0022389171 scopus 로고
    • Cholesterol and the cell membrane
    • Yeagle P.L. Cholesterol and the cell membrane. Biochim Biophys Acta 822 (1985) 267-287
    • (1985) Biochim Biophys Acta , vol.822 , pp. 267-287
    • Yeagle, P.L.1
  • 28
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
    • Okamoto T., Schlegel A., Scherer P.E., and Lisanti M.P. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem 273 (1998) 5419-5422
    • (1998) J Biol Chem , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 29
    • 0027930938 scopus 로고
    • The effect of sarcolemmal cholesterol content on intracellular calcium ion concentration in cultured cardiomyocytes
    • Bastiaanse E.M., Atsma D.E., Kuijpers M.M., and Van der Laarse A. The effect of sarcolemmal cholesterol content on intracellular calcium ion concentration in cultured cardiomyocytes. Arch Biochem Biophys 313 (1994) 58-63
    • (1994) Arch Biochem Biophys , vol.313 , pp. 58-63
    • Bastiaanse, E.M.1    Atsma, D.E.2    Kuijpers, M.M.3    Van der Laarse, A.4
  • 30
    • 0346096805 scopus 로고    scopus 로고
    • Cardiac systolic and diastolic dysfunction after a cholesterol-rich diet
    • Huang Y., Walker K.E., Hanley F., et al. Cardiac systolic and diastolic dysfunction after a cholesterol-rich diet. Circulation 109 (2004) 97-102
    • (2004) Circulation , vol.109 , pp. 97-102
    • Huang, Y.1    Walker, K.E.2    Hanley, F.3
  • 31
    • 10844269467 scopus 로고    scopus 로고
    • Effect of hypercholesterolemia on myocardial function in New Zealand white rabbits
    • Luo T.Y., Su M.J., Yang Y.F., et al. Effect of hypercholesterolemia on myocardial function in New Zealand white rabbits. J Biomed Sci 11 (2004) 829-837
    • (2004) J Biomed Sci , vol.11 , pp. 829-837
    • Luo, T.Y.1    Su, M.J.2    Yang, Y.F.3


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