Tyr-51 is the proton donor-acceptor for NAD(H)-dependent interconversion of xylose and xylitol by Candida tenuis xylose reductase (AKR2B5)

FEBS Letters

Volumn 582, Issue 29, 2008, Pages 4095-4099

  Pival, Simone L ^a   Klimacek, Mario ^a   Kratzer, Regina ^a   Nidetzky, Bernd ^a  

^a GRAZ UNIVERSITY OF TECHNOLOGY   (Austria)

Author keywords

AKR2B5; Aldo keto reductase; Br nsted catalysis; Catalytic mechanism; pH study; Unidirectional chemical rescue; Xylose reductase

Indexed keywords

ALCOHOL; BROMIDE; HOLOENZYME; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; TYROSINE; XYLITOL; XYLOSE;

AMINO ACID SUBSTITUTION; ARTICLE; CANDIDA; CANDIDA TENUIS; CATALYSIS; ENZYME ACTIVITY; ENZYME BINDING; HYDROGEN BOND; NONHUMAN; OXIDATION; PRIORITY JOURNAL;

ALANINE; ALDEHYDE REDUCTASE; AMINO ACID SUBSTITUTION; CANDIDA; HYDROGEN BONDING; HYDROGEN-ION CONCENTRATION; KINETICS; NAD; PROTONS; TYROSINE; XYLITOL; XYLOSE;

CANDIDA TENUIS;

EID: 56649109630     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.11.003     Document Type: Article

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