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Volumn 92, Issue 5, 2004, Pages 848-863

Engineering in the biological substrate: Information processing in genetic circuits

Author keywords

Gene circuit simulation; Gene circuits; Stochastic gene expression analysis; Synthetic biology; Systems biology

Indexed keywords

CELLS; COMPUTER SIMULATION; ESCHERICHIA COLI; FEEDBACK; GENES; MATHEMATICAL MODELS; NETWORKS (CIRCUITS); NEURAL NETWORKS; OSCILLATORS (ELECTRONIC); SEMICONDUCTOR DEVICES;

EID: 5644289657     PISSN: 00189219     EISSN: None     Source Type: Journal    
DOI: 10.1109/JPROC.2004.826600     Document Type: Conference Paper
Times cited : (41)

References (80)
  • 1
  • 3
    • 0042045214 scopus 로고    scopus 로고
    • Whole cell biosensors
    • L. Bousse, "Whole cell biosensors," Sens. Actuators B, Chem., vol. 34, pp. 270-275, 1996.
    • (1996) Sens. Actuators B, Chem. , vol.34 , pp. 270-275
    • Bousse, L.1
  • 4
    • 0034226255 scopus 로고    scopus 로고
    • Genetically engineered whole-cell sensing systems coupling biological recognition with reporter genes
    • S. Daunen, G. Barrett, J. S. Feliciano, R. S. Shetty, S. Shrestha, and W. Smith-Spencer, "Genetically engineered whole-cell sensing systems coupling biological recognition with reporter genes," Chem. Rev., vol. 100, pp. 2705-2738, 2000.
    • (2000) Chem. Rev. , vol.100 , pp. 2705-2738
    • Daunen, S.1    Barrett, G.2    Feliciano, J.S.3    Shetty, R.S.4    Shrestha, S.5    Smith-Spencer, W.6
  • 5
    • 0037141790 scopus 로고    scopus 로고
    • Integrated CMOS photodetectors and signal processing for very low-level chemical sensing with the bioluminesceni bioreporter integrated circuit
    • E. K. Bolton, G. S. Sayler, D. E. Nivens, J. M. Rochelle, S. Ripp, and M. L. Simpson, "Integrated CMOS photodetectors and signal processing for very low-level chemical sensing with the bioluminesceni bioreporter integrated circuit," Sens. Actuators B, Chem., vol. 85, pp. 179-185, 2002.
    • (2002) Sens. Actuators B, Chem. , vol.85 , pp. 179-185
    • Bolton, E.K.1    Sayler, G.S.2    Nivens, D.E.3    Rochelle, J.M.4    Ripp, S.5    Simpson, M.L.6
  • 7
    • 0036207347 scopus 로고    scopus 로고
    • Modeling and simulation of genetic regulatory systems: A literature review
    • H. De Jong, "Modeling and simulation of genetic regulatory systems: a literature review," J. Comput. Biol., vol. 9, pp. 67-103, 2002.
    • (2002) J. Comput. Biol. , vol.9 , pp. 67-103
    • De Jong, H.1
  • 8
    • 0031879114 scopus 로고
    • Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells
    • A. Arkin, J. Ross, and H. H. McAdams, "Stochastic kinetic analysis of developmental pathway bifurcation in phage lambda-infected Escherichia coli cells," Genetics, vol. 149, pp. 1633-1648, 1948.
    • (1948) Genetics , vol.149 , pp. 1633-1648
    • Arkin, A.1    Ross, J.2    McAdams, H.H.3
  • 9
    • 0034625007 scopus 로고    scopus 로고
    • Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes
    • D. Endy, L. C. You, J. Yin, and I. J. Molineux, "Computation, prediction, and experimental tests of fitness for bacteriophage T7 mutants with permuted genomes," Proc. Nat. Acad. Sci., vol. 97, pp. 5375-5380, 2000.
    • (2000) Proc. Nat. Acad. Sci. , vol.97 , pp. 5375-5380
    • Endy, D.1    You, L.C.2    Yin, J.3    Molineux, I.J.4
  • 10
    • 0035905782 scopus 로고    scopus 로고
    • Modeling cellular behavior
    • D. Endy and R. Brent, "Modeling cellular behavior," Nature, vol. 409, pp. 391-395, 2001.
    • (2001) Nature , vol.409 , pp. 391-395
    • Endy, D.1    Brent, R.2
  • 11
    • 0029028963 scopus 로고
    • Circuit simulation of genetic networks
    • H. H. Mcadams and K. Shapiro, "Circuit simulation of genetic networks," Science, vol. 269, pp. 650-656, 1995.
    • (1995) Science , vol.269 , pp. 650-656
    • Mcadams, H.H.1    Shapiro, K.2
  • 13
    • 0033782304 scopus 로고    scopus 로고
    • Modeling transcriptional control in gene networks - Methods, recent results, and future directions
    • P. Smolen, D. A. Baxter, and J. H. Byrne, "Modeling transcriptional control in gene networks - Methods, recent results, and future directions," Bull. Math. Biol., vol. 62, pp. 247-292, 2000.
    • (2000) Bull. Math. Biol. , vol.62 , pp. 247-292
    • Smolen, P.1    Baxter, D.A.2    Byrne, J.H.3
  • 14
    • 0037447260 scopus 로고    scopus 로고
    • Frequency domain analysis of noise in autoregulated gene circuits
    • M- L. Simpson, C. D. Cox, and G. S. Sayler, "Frequency domain analysis of noise in autoregulated gene circuits," in Proc. Nat. Acad. Sci., vol. 100, 2003, pp. 4551-4556.
    • (2003) Proc. Nat. Acad. Sci. , vol.100 , pp. 4551-4556
    • Simpson, M.L.1    Cox, C.D.2    Sayler, G.S.3
  • 15
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • M. B. Elowitz and S. Leibler, "A synthetic oscillatory network of transcriptional regulators," Nature, vol. 403, pp. 335-338, 2000.
    • (2000) Nature , vol.403 , pp. 335-338
    • Elowitz, M.B.1    Leibler, S.2
  • 16
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • T. S. Gardner, C. R. Cantor, and J. J. Collins, "Construction of a genetic toggle switch in Escherichia coli," Nature, vol. 403, pp. 339-342, 2000.
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 17
    • 0037165942 scopus 로고    scopus 로고
    • Combinatorial synthesis of genetic networks
    • C. C. Guet, M. B. Elowitz, W. H. Hsing, and S. Leibler, "Combinatorial synthesis of genetic networks," Science, vol. 296, pp. 1466-1470, 2002.
    • (2002) Science , vol.296 , pp. 1466-1470
    • Guet, C.C.1    Elowitz, M.B.2    Hsing, W.H.3    Leibler, S.4
  • 18
    • 0037079012 scopus 로고    scopus 로고
    • Engineered gene circuits
    • J. Hasty, D. McMillen, and J. J. Collins, "Engineered gene circuits," Nature, vol. 420, pp. 224-230, 2002.
    • (2002) Nature , vol.420 , pp. 224-230
    • Hasty, J.1    McMillen, D.2    Collins, J.J.3
  • 19
    • 0037041888 scopus 로고    scopus 로고
    • Synthetic gene network for entraining and amplifying cellular oscillations
    • J. Hasty, M. Dolnik, V. Rottschafer, and J. J. Collins, "Synthetic gene network for entraining and amplifying cellular oscillations," Phys. Rev. Lett., vol. 88, pp. 1148101-1-148101-4, 2002.
    • (2002) Phys. Rev. Lett. , vol.88 , pp. 11481011-11481014
    • Hasty, J.1    Dolnik, M.2    Rottschafer, V.3    Collins, J.J.4
  • 20
    • 0034045290 scopus 로고    scopus 로고
    • Toggles and oscillators: New genetic circuit designs
    • E. M. Judd, M. T. Laub, and H. H. McAdams, "Toggles and oscillators: new genetic circuit designs," Bioessays, vol. 22, pp. 507-509, 2000.
    • (2000) Bioessays , vol.22 , pp. 507-509
    • Judd, E.M.1    Laub, M.T.2    McAdams, H.H.3
  • 26
    • 0004211673 scopus 로고    scopus 로고
    • Cold Spring Harbor, NY: Cold Spring Harbor Lab.
    • M. Ptashne and A. Gann, Genes and Signals. Cold Spring Harbor, NY: Cold Spring Harbor Lab., 2001.
    • (2001) Genes and Signals
    • Ptashne, M.1    Gann, A.2
  • 29
    • 0024961654 scopus 로고
    • A novel structured kinetic modeling approach for the analysis of plasmid instability in recombinant bacterial cultures
    • W. E. Bentley and D. S. Kompala, "A novel structured kinetic modeling approach for the analysis of plasmid instability in recombinant bacterial cultures," Biotechnol. Bioeng., vol. 33, pp. 49-61, 1989.
    • (1989) Biotechnol. Bioeng. , vol.33 , pp. 49-61
    • Bentley, W.E.1    Kompala, D.S.2
  • 30
    • 0014089490 scopus 로고
    • A model of cell growth dynamics
    • F. M. Williams, "A model of cell growth dynamics," J. Theor. Biol., vol. 15, pp. 190-207, 1967.
    • (1967) J. Theor. Biol. , vol.15 , pp. 190-207
    • Williams, F.M.1
  • 31
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • M. B. Elowitz, A. J. Levine, E. D. Siggia, and P. S. Swain, "Stochastic gene expression in a single cell," Science, vol. 297, pp. 1183-1186, 2002.
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3    Swain, P.S.4
  • 32
    • 0035896577 scopus 로고    scopus 로고
    • The effect of transcription and translation initiation frequencies on the stochastic fluctuations in prokaryotic gene expression
    • A. M. Kierzek, J. Zaim, and P. Zielenkiewicz, "The effect of transcription and translation initiation frequencies on the stochastic fluctuations in prokaryotic gene expression," J. Biol. Chem., vol. 276, pp. 8165-8172, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8165-8172
    • Kierzek, A.M.1    Zaim, J.2    Zielenkiewicz, P.3
  • 33
    • 73049167504 scopus 로고
    • General conclusions: Teleonomic mechanisms in cellular metabolism, growth and differentiation
    • J. F. Monod, "General conclusions: teleonomic mechanisms in cellular metabolism, growth and differentiation," in Proc. Cold Spring Harbor Symp. Quantitative Biology, vol. 26, 1961, pp. 389-401.
    • (1961) Proc. Cold Spring Harbor Symp. Quantitative Biology , vol.26 , pp. 389-401
    • Monod, J.F.1
  • 36
    • 0037079012 scopus 로고    scopus 로고
    • Engineered gene circuits
    • J. Hasty, D. McMillen, and J. J. Collins, "Engineered gene circuits," Nature, vol. 420, pp. 224-230, 2002.
    • (2002) Nature , vol.420 , pp. 224-230
    • Hasty, J.1    McMillen, D.2    Collins, J.J.3
  • 37
    • 0006092502 scopus 로고    scopus 로고
    • Designer gene networks: Toward fundamental cellular control
    • J. Hasty, F. Isaacs, M. Dolnik, D. McMillen, and J. J. Collins, "Designer gene networks: toward fundamental cellular control," Chaos, vol. 11, pp. 207-220, 2001.
    • (2001) Chaos , vol.11 , pp. 207-220
    • Hasty, J.1    Isaacs, F.2    Dolnik, M.3    McMillen, D.4    Collins, J.J.5
  • 39
    • 2242423161 scopus 로고    scopus 로고
    • The device physics of cellular logic gates
    • Boston, MA
    • R. Weiss and S. Basu, "The device physics of cellular logic gates," presented at the 1st Workshop Non-Silicon Computing, Boston, MA, 2002.
    • (2002) 1st Workshop Non-silicon Computing
    • Weiss, R.1    Basu, S.2
  • 40
  • 41
    • 0037154293 scopus 로고    scopus 로고
    • Synchronizing genetic relaxation oscillators by intercell signaling
    • D. McMillen, N. Kopell, J. Hasty, and J. J. Collins, "Synchronizing genetic relaxation oscillators by intercell signaling," in Proc. Nat. Acad. Sci., vol. 99, 2002, pp. 679-684.
    • (2002) Proc. Nat. Acad. Sci. , vol.99 , pp. 679-684
    • McMillen, D.1    Kopell, N.2    Hasty, J.3    Collins, J.J.4
  • 42
    • 0038454434 scopus 로고    scopus 로고
    • Circadian clocks in daily and seasonal control of development
    • T. F. Schultz and S. A. Kay, "Circadian clocks in daily and seasonal control of development," Science, vol. 301, pp. 326-328, 2003.
    • (2003) Science , vol.301 , pp. 326-328
    • Schultz, T.F.1    Kay, S.A.2
  • 43
    • 0037965981 scopus 로고    scopus 로고
    • On schemes of combinatorial transcription logic
    • N. E. Buchler, U. Gerland, and T. Hwa, "On schemes of combinatorial transcription logic," Proc. Nat. Acad. Sci., vol. 100, pp. 5136-5141, 2003.
    • (2003) Proc. Nat. Acad. Sci. , vol.100 , pp. 5136-5141
    • Buchler, N.E.1    Gerland, U.2    Hwa, T.3
  • 44
    • 0037126028 scopus 로고    scopus 로고
    • Physical constraints and functional characteristics of transcription factor-DNA interaction
    • U. Gerland, J. D. Moroz, and T. Hwa, "Physical constraints and functional characteristics of transcription factor-DNA interaction," Proc. Nat. Acad. Sci., vol. 99, pp. 12015-12020, 2002.
    • (2002) Proc. Nat. Acad. Sci. , vol.99 , pp. 12015-12020
    • Gerland, U.1    Moroz, J.D.2    Hwa, T.3
  • 45
    • 0036578795 scopus 로고    scopus 로고
    • Network motifs in the transcriptional regulation network of Escherichia coli
    • S. S. Shen-Orr, R. Milo, S. Mangan, and U. Alon, "Network motifs in the transcriptional regulation network of Escherichia coli," Nature Genet., vol. 31, pp. 64-68, 2002.
    • (2002) Nature Genet. , vol.31 , pp. 64-68
    • Shen-Orr, S.S.1    Milo, R.2    Mangan, S.3    Alon, U.4
  • 48
    • 0035902599 scopus 로고    scopus 로고
    • Intrinsic noise in gene regulatory networks
    • M. Thattai and A. van Oudenaarden, "Intrinsic noise in gene regulatory networks," Proc. Nat. Acad. Sci., vol. 98, pp. 8614-8619, 2001.
    • (2001) Proc. Nat. Acad. Sci. , vol.98 , pp. 8614-8619
    • Thattai, M.1    Van Oudenaarden, A.2
  • 51
    • 0032485809 scopus 로고    scopus 로고
    • Modeling M-phase control in Xenopus oocyte extracts: The surveillance mechanism for unreplicated DNA
    • G. Marlovits, C. J. Tyson, B. Novak, and J. J. Tyson, "Modeling M-phase control in Xenopus oocyte extracts: the surveillance mechanism for unreplicated DNA," Biophys. Chem., vol. 72, pp. 169-184, 1998.
    • (1998) Biophys. Chem. , vol.72 , pp. 169-184
    • Marlovits, G.1    Tyson, C.J.2    Novak, B.3    Tyson, J.J.4
  • 52
    • 0027451906 scopus 로고
    • Modeling the celt-division cycle-M-phase trigger, oscillations, and size control
    • B. Novak and J. J. Tyson, "Modeling the celt-division cycle-M-phase trigger, oscillations, and size control," J. Theor. Biol., vol. 165, pp. 101-134, 1993.
    • (1993) J. Theor. Biol. , vol.165 , pp. 101-134
    • Novak, B.1    Tyson, J.J.2
  • 54
    • 0342506826 scopus 로고    scopus 로고
    • Intracellular kinetics of a growing virus: A genetically structured simulation for bacteriophage T7
    • D. Endy, D. Kong, and J. Yin, "Intracellular kinetics of a growing virus: a genetically structured simulation for bacteriophage T7," Biotechnol. Bioeng., vol. 55, pp. 375-389, 1997.
    • (1997) Biotechnol. Bioeng. , vol.55 , pp. 375-389
    • Endy, D.1    Kong, D.2    Yin, J.3
  • 56
    • 0037078982 scopus 로고    scopus 로고
    • Control, exploitation and tolerance of intracellular noise
    • C. V. Rao, D. M. Wolf, and A. P. Arkin, "Control, exploitation and tolerance of intracellular noise," Nature, vol. 420, pp. 231-237, 2002.
    • (2002) Nature , vol.420 , pp. 231-237
    • Rao, C.V.1    Wolf, D.M.2    Arkin, A.P.3
  • 57
    • 0034225547 scopus 로고    scopus 로고
    • The chemical Langevin equation
    • D. T. Gillespie, "The chemical Langevin equation," J. Chem. Phys., vol. 113, pp. 297-306, 2000.
    • (2000) J. Chem. Phys. , vol.113 , pp. 297-306
    • Gillespie, D.T.1
  • 58
    • 0003781238 scopus 로고    scopus 로고
    • Cambridge, U.K.: Cambridge Univ. Press
    • J. R. Norris, Markov Chains. Cambridge, U.K.: Cambridge Univ. Press, 1998.
    • (1998) Markov Chains
    • Norris, J.R.1
  • 59
    • 0037162152 scopus 로고    scopus 로고
    • The chemical Langevin and Fokker-Planck equations for the reversible isomerization reaction
    • D. T. Gillespie, "The chemical Langevin and Fokker-Planck equations for the reversible isomerization reaction," J. Phys. Chem. A, vol. 106, pp. 5063-5071, 2002.
    • (2002) J. Phys. Chem. A , vol.106 , pp. 5063-5071
    • Gillespie, D.T.1
  • 60
    • 0034212551 scopus 로고    scopus 로고
    • Engineering stability in gene networks by autoregulation
    • A. Becskei and L. Serrano, "Engineering stability in gene networks by autoregulation," Nature, vol. 405, pp. 590-593, 2000.
    • (2000) Nature , vol.405 , pp. 590-593
    • Becskei, A.1    Serrano, L.2
  • 61
    • 0035193294 scopus 로고    scopus 로고
    • Stochasticity in transcriptional regulation: Origins, consequences, and mathematical representations
    • T. B. Kepler and T. C. Elston, "Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations," Biophys. J., vol. 81, pp. 3116-3136, 2001.
    • (2001) Biophys. J. , vol.81 , pp. 3116-3136
    • Kepler, T.B.1    Elston, T.C.2
  • 62
    • 0037206807 scopus 로고    scopus 로고
    • Signal processing by simple chemical systems
    • M. Samoilov, A. Arkin, and J. Ross, "Signal processing by simple chemical systems," J. Phys. Chem. A, vol. 106, pp. 10205-10221, 2002.
    • (2002) J. Phys. Chem. A , vol.106 , pp. 10205-10221
    • Samoilov, M.1    Arkin, A.2    Ross, J.3
  • 63
    • 33645429016 scopus 로고
    • Exact stochastic simulation of coupled chemical-reactions
    • D. T. Gillespie, "Exact stochastic simulation of coupled chemical-reactions," J. Phys. Chem., vol. 81, pp. 2340-2361, 1977.
    • (1977) J. Phys. Chem. , vol.81 , pp. 2340-2361
    • Gillespie, D.T.1
  • 64
    • 0017030517 scopus 로고
    • General method for numerically simulating stochastic time evolution of coupled chemical-reactions
    • _, "General method for numerically simulating stochastic time evolution of coupled chemical-reactions," J. Comput. Phys., vol. 22, pp. 403-434, 1976.
    • (1976) J. Comput. Phys. , vol.22 , pp. 403-434
  • 65
    • 0001144902 scopus 로고    scopus 로고
    • Efficient exact stochastic simulation of chemical systems with many species and many channels
    • M. A. Gibson and J. Bruck, "Efficient exact stochastic simulation of chemical systems with many species and many channels," J. Phys. Chem. A, vol. 104, pp. 1876-1889, 2000.
    • (2000) J. Phys. Chem. A , vol.104 , pp. 1876-1889
    • Gibson, M.A.1    Bruck, J.2
  • 67
    • 0035933994 scopus 로고    scopus 로고
    • Approximate accelerated stochastic simulation of chemically reacting systems
    • D. T. Gillespie, "Approximate accelerated stochastic simulation of chemically reacting systems," J. Chem. Phys., vol. 115, pp. 1716-1733, 2001.
    • (2001) J. Chem. Phys. , vol.115 , pp. 1716-1733
    • Gillespie, D.T.1
  • 69
    • 0015526205 scopus 로고
    • Chemotaxis in Escherichia-coli analyzed by three-dimensional tracking
    • H. C. Berg and D. A. Brown, "Chemotaxis in Escherichia-coli analyzed by three-dimensional tracking," Nature, vol. 239, pp. 500-504, 1972.
    • (1972) Nature , vol.239 , pp. 500-504
    • Berg, H.C.1    Brown, D.A.2
  • 70
    • 0015397646 scopus 로고
    • Gradient-sensing mechanism in bacterial chemotaxis
    • R. M. Macnab and D. E. Koshland, "Gradient-sensing mechanism in bacterial chemotaxis," Proc. Nat. Acad. Sci., vol. 69, pp. 2509-2512, 1972.
    • (1972) Proc. Nat. Acad. Sci. , vol.69 , pp. 2509-2512
    • Macnab, R.M.1    Koshland, D.E.2
  • 71
    • 0033552946 scopus 로고    scopus 로고
    • Robustness in bacterial chemotaxis
    • U. Alon, M. G. Surette, N. Barkai, and S. Leibler, "Robustness in bacterial chemotaxis," Nature, vol. 397, pp. 168-171, 1999.
    • (1999) Nature , vol.397 , pp. 168-171
    • Alon, U.1    Surette, M.G.2    Barkai, N.3    Leibler, S.4
  • 72
    • 0030797355 scopus 로고    scopus 로고
    • Robustness in simple biochemical networks
    • N. Barkai and S. Leibler, "Robustness in simple biochemical networks," Nature, vol. 387, pp. 913-917, 1997.
    • (1997) Nature , vol.387 , pp. 913-917
    • Barkai, N.1    Leibler, S.2
  • 73
    • 0034712843 scopus 로고    scopus 로고
    • Robust perfect adaptation in bacterial chemotaxis through integral feedback control
    • T. M. Yi, Y. Huang, M. I. Simon, and J. Doyle, "Robust perfect adaptation in bacterial chemotaxis through integral feedback control," Proc. Nat. Acad. Sci., vol. 97, pp. 4649-4653, 2000.
    • (2000) Proc. Nat. Acad. Sci. , vol.97 , pp. 4649-4653
    • Yi, T.M.1    Huang, Y.2    Simon, M.I.3    Doyle, J.4
  • 74
    • 0037108904 scopus 로고    scopus 로고
    • Natural alleles at a tomato fruit size quantitative trail locus differ by heterochronic regulatory mutations
    • B. Cong, J. Liu, and S. D. Tanksley, "Natural alleles at a tomato fruit size quantitative trail locus differ by heterochronic regulatory mutations," Proc. Nat. Acad. Sci., vol. 99, pp. 13606-13611, 2002.
    • (2002) Proc. Nat. Acad. Sci. , vol.99 , pp. 13606-13611
    • Cong, B.1    Liu, J.2    Tanksley, S.D.3
  • 75
    • 0033083733 scopus 로고    scopus 로고
    • It's a noisy business! Genetic regulation at the nanomolar scale
    • H. H. McAdams and A. Arkin, "It's a noisy business! Genetic regulation at the nanomolar scale," Trends Genet., vol. 15, pp. 65-69, 1999.
    • (1999) Trends Genet. , vol.15 , pp. 65-69
    • McAdams, H.H.1    Arkin, A.2
  • 76
    • 0031029852 scopus 로고    scopus 로고
    • Stochastic mechanisms in gene expression
    • _, "Stochastic mechanisms in gene expression," Proc. Nat. Acad. Sci., vol. 94, pp. 814-819, 1997.
    • (1997) Proc. Nat. Acad. Sci. , vol.94 , pp. 814-819
  • 77
    • 0036500834 scopus 로고    scopus 로고
    • Reverse engineering of biological complexity
    • M. E. Csete and J. C. Doyle, "Reverse engineering of biological complexity," Science, vol. 295, pp. 1664-1669, 2002.
    • (2002) Science , vol.295 , pp. 1664-1669
    • Csete, M.E.1    Doyle, J.C.2
  • 78
    • 0032077377 scopus 로고    scopus 로고
    • From specific gene regulation to genomic networks: A global analysis of transcriptional regulation in Escherichia coli
    • D. Thieffry, A. M. Huerta, E. Perez-Rueda, and J. Collado-Vides, "From specific gene regulation to genomic networks: a global analysis of transcriptional regulation in Escherichia coli," Bioessays, vol. 20, pp. 433-440, 1998.
    • (1998) Bioessays , vol.20 , pp. 433-440
    • Thieffry, D.1    Huerta, A.M.2    Perez-Rueda, E.3    Collado-Vides, J.4
  • 79
    • 0036428761 scopus 로고    scopus 로고
    • Negative auloregulation speeds the response times of transcription networks
    • N. Rosenfeld, M. B. Elowitz, and U. Alon, "Negative auloregulation speeds the response times of transcription networks," J. Mol. Biol., vol. 323, pp. 785-793, 2002.
    • (2002) J. Mol. Biol. , vol.323 , pp. 785-793
    • Rosenfeld, N.1    Elowitz, M.B.2    Alon, U.3
  • 80
    • 84980081376 scopus 로고
    • Stabilized feedback amplifiers
    • H. S. Black, "Stabilized feedback amplifiers," Bell Syst. Tech. J., vol. 13, p. 3, 1934.
    • (1934) Bell Syst. Tech. J. , vol.13 , pp. 3
    • Black, H.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.