Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 24, 2008, Pages 10319-10325

  Hoettecke, Nicole ^a   Rotzoll, Sven ^a   Albrecht, Uwe ^a   Lalk, Michael ^b   Fischer, Christine ^c   Langer, Peter ^a,c  

^a UNIVERSITY OF ROSTOCK   (Germany)

^b UNIVERSITY OF GREIFSWALD   (Germany)

^c LEIBNIZ INSTITUT FÜR KATALYSE E V AN DER UNIVERSITÄT ROSTOCK   (Germany)

Author keywords

Antimicrobial activity; Chromanones; Heterocycles

Indexed keywords

2 VINYLCHROMAN 4 ONE DERIVATIVE; 4 CHROMANONE DERIVATIVE; QUINOL 4 ONE DERIVATIVE; THIOCHROMAN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; DRUG CONJUGATION; DRUG SCREENING; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; NONHUMAN;

ANTI-BACTERIAL AGENTS; BACILLUS SUBTILIS; CHROMONES; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; STAPHYLOCOCCUS AUREUS; YEASTS;

EID: 56349150862     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.10.043     Document Type: Article

References (22)

1. Rachakonda S., and Cartee L. Curr. Med. Chem. 11 (2004) 775
2. Walsh C. Antibiotics, Actions, Origins, Resistance (2003), ASM, Washington, DC
3. World Health Organisation (WHO) Geneva, World Health Report-2002, 2002.
4. Nathan C. Nature 431 (2004) 899
5. Review:. von Nussbaum F., Brands M., Hinzen B., Weigand S., and Häbich D. Angew. Chem. Int. Ed. 45 (2006) 5072
6. Review:. Barbachyn M.R., and Ford C.W. Angew. Chem. 115 (2003) 2056
7. Angew. Chem. Int. Ed. 2003, 42, 2010.
8. Raja A., LaBonte J., Lebbos J., and Kirkpatrick P. Nat. Rev. Drug Disc. 2 (2003) 943
9. Alder J.D. Drugs Today 41 (2005) 81
10. Krohn K., Michel A., Bahramsari R., Floerke U., Aust H.J., Draeger S., Schulz B., and Wray V. Nat. Prod. Lett. 8 (1996) 43
11. Pari K., Rao P.J., Subrahmanyam B., Rasthogi J.N., and Devakumar C. Phytochemistry 49 (1998) 1385
12. Evidente A. J. Nat. Prod. 50 (1987) 173
13. Wijeratne E.M.K., Paranagama P.A., and Gunatilaka A.A.L. Tetrahedron 62 (2006) 8439
14. For synthetic 2-vinylchroman-4-ones, see:. Karton Y., Jiang J.-l., Ji X.-D., Melman N., Olah M.E., Stiles G.L., and Jacobson K.A. J. Med. Chem. 39 (1996) 2293
15. Ye T., Garcia C.F., and McKervey M.A. J. Chem. Soc., Perkin Trans. 1 (1995) 1373
16. Gallois E., and Defoin A. Bull. Soc. Chim. Belg. 106 (1997) 273
17. De M., Majumdar D.P., and Kundu N.G. J. Indian Chem. Soc. 76 (1999) 665
18. Puranik R., Rao Y.J., and Krupadanam G.D.L. Indian J. Chem. B 41 (2002) 868
19. Lalk, M.; Albrecht, U.; Langer, P. Intern. Patent PCT WO 2004/113317 A1, 29.12.2004, Anmeldetag 20.6.2003.
20. Albrecht U., Lalk M., and Langer P. Bioorg. Med. Chem. 13 (2005) 1531
21. Langer P. Chim. Oggi/Chem. Today 26 (2008) 9
22. Nguyen V.D., Wolf C., Mäder U., Lalk M., Langer P., Lindequist U., Hecker M., and Antelmann H. Proteomics 7 (2007) 1391