A novel DNA vaccine-targeting macrophage migration inhibitory factor improves the survival of mice with sepsis

Gene Therapy

Volumn 15, Issue 23, 2008, Pages 1513-1522

  Tohyama, S ^a   Onodera, S ^a   Tohyama, H ^a   Yasuda, K ^a   Nishihira, J ^b   Mizue, Y ^c   Hamasaka, A ^a   Abe, R ^a   Koyama, Y ^b  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HOKKAIDO INFORMATION UNIVERSITY   (Japan)

^c Sapporo Immuno Diagnostic Laboratory   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 2; MACROPHAGE MIGRATION INHIBITION FACTOR; MESSENGER RNA; TETANUS TOXIN; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ADAPTIVE IMMUNITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; ENDOTOXEMIA; GENE EXPRESSION; HUMORAL IMMUNITY; IMMUNOREGULATION; IMMUNOSTIMULATION; INNATE IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; SEPSIS; SURVIVAL; WOUND HEALING;

ANIMALS; ANTIBODIES; BIOLOGICAL MARKERS; CECUM; CHEMOKINE CXCL2; GENE THERAPY; INTERLEUKIN-6; LIGATION; LIPOPOLYSACCHARIDES; LUNG; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MACROPHAGES; MICE; MICE, INBRED BALB C; MODELS, ANIMAL; SHOCK, SEPTIC; SKIN; TOLL-LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR-ALPHA; VACCINES, DNA; WOUND HEALING;

MUS; RATTUS;

EID: 56349138520     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2008.112     Document Type: Article

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