The integrate model of emotion, thinking and self regulation: An application to the "paradox of aging"

Journal of Integrative Neuroscience

Volumn 7, Issue 3, 2008, Pages 367-404

  Williams, Leanne M ^a   Gatt, Justine M ^a   Hatch, Ainslie ^a   Palmer, Donna M ^a   Nagy, Marie ^a   Rennie, Christopher ^a   Cooper, Nicholas J ^b   Morris, Charlotte ^b   Grieve, Stuart ^a   Dobson Stone, Carol ^c   Schofield, Peter ^c   Clark, C Richard ^d   Gordon, Evian ^a,b   Arns, Martijn ^e   Paul, Robert H ^f  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Brain Resource Company   (Australia)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

^d FLINDERS UNIVERSITY   (Australia)

^e RESEARCH INSTITUTE BRAINCLINICS   (Netherlands)

^f SAINT LOUIS UNIVERSITY   (United States)

Author keywords

Age; Cognition; EEG and ERPs; Emotion; Genetic polymorphism; Integrative neuroscience; MRI; Psychiatric disorder; Self regulation; Thinking

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; BRAIN DERIVED NEUROTROPHIC FACTOR; CATECHOL METHYLTRANSFERASE; DOPAMINE 4 RECEPTOR; METHIONINE; SEROTONIN TRANSPORTER; VALINE;

ADOLESCENT; ADULT; AGE; AGED; AGING; ARTICLE; AUTOREGULATION; CHILD; CONTROLLED STUDY; EMOTION; FEMALE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GRAY MATTER; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; LIFESPAN; MALE; MODEL; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TANDEM REPEAT; THINKING;

EID: 56349119377     PISSN: 02196352     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0219635208001939     Document Type: Article

References (90)

1. Adolphs R, Neural systems for recognizing emotion, Curr Opin Neurobiol 12:169-177, 2002.
2. Amenedo E, Diaz F, Automatic and effortful processes in auditory memory reflected by event-related potentials: Age related findings, Electroencephalogr Clin Neurophysiol 108:361-369, 1998.
3. Ashburner J, Andersson JL, Riston KJ, Image registration using a symmetric prior - in three dimensions, Hum Brain Mapp 9 212-225, 2000.
4. Baddeley AD, Hitch GJ, Working memory, in GA Bower (ed.), The Psychology of Learning and Motivation: Advances in Research and Theory Academic Press, New York, pp. 47-90, 1974.
5. Brown GDA, Neath I, Chater N, A ratio model of scale-invariant memory and identification, Psychol Rev 114:539-576, 2007.
6. Carstensen LL, Lockenhoff CE, Aging, emotion, and evolution: The bigger picture, Ann NY Acad Sci 1000:152-179, 2000.
7. Catani M, Jones DK, Donato R, Ffytche DIL Occipito-temporal connections in the human brain, Brain 126:2093-2107, 2003.
8. Clark CR, Moores KA, Lewis A, Weber DL, Fitzgibbon S, Greenblatt R, Brown G, Taylor J, Cortical network dynamics during verbal working memory function, Int J Psychophysiol 42:161-176, 2001.
9. Clark CR, Paul RIL Williams LM, Arns M, Fallahpour K, Handmer C, Gordon E, Standardized assessment of cognitive functioning during development and aging using an automated touchscreen battery, Arch Clin Neuropsychol 21:449-467, 2006.
10. Comoli E, Coizet V, Boyes J, Bolam JP, Canteras NS, Quirk RH et al. A direct projection from superior colliculus to substantia nigra for detecting salient visual events, Nat Neurosci 6:974-980, 2003.
11. Damasio AR, Descartes' Error. Emotion, Reason, and the Human Brain Grosset/Putnam, New York, 1994.
12. Damasio AR, The somatic marker hypothesis and the possible functions of the prefrontal cortex, Philo Trans R Soc Land B Biol Sci B351 1413-1420, 1996.
13. Darwin C, The Expression of the Emotions in Man and Animals, 3rd ed., Ekman P (ed.), Oxford University Press, New York, 1872/1998.
14. Davidson RJ, Irwin W, The functional neuroanatomy of emotion and affective style, Trends Cogn Sci 3:11-21, 1999.
15. Edelman GM, Bright Air, Brilliant Fire. On the Matter of Mind, Basic Books, USA, 1992.
16. Egan MF, Goldberg TE, Kolachana BS, Callicott JH, Mazzanti CM, Straub RE, Goldman D, Weinberger DR, Effect of COMT Val108/158Met genotype on frontal lobe function and risk for schizophrenia, Proc Natl Acad Sci USA 98:6917-6922, 2001.
17. Egan MF, Kojima M, Callicott JH et al., The BDNF Val66Met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function, Cell 112:257-269, 2003.
18. Ekman P, Emotion in the Human Face, Cambridge University Press, Cambridge, 1982.
19. Fridland AJ, Human Facial Expression: An Evolutionary View, Academic Press, London, 1994.
20. Friston KJ, Ashburner J, Frith CD, Poline J-B, Heather JD, Frackowiak RSJ, Spatial registration and normalization of images, Hum Brain Mapp 2:189-210, 1995.
21. Gatt JM, Clark CR, Kemp AH et al., A Genotype-endophenotype-phenotype path model of depressed mood: Integrating cognitive and emotional markers, J Integr Neurosci 6:75-104, 2007.
22. Gatt JM, Kuan SA, Dobson-Stone C, Paul RIL Joffe RT, Kemp AIL Gordon E, Schofield PR, Williams LM, Association between BDNF Val66Met polymorphism and trait depression is mediated via resting EEG alpha band activity, Biological Psychology, in press.
23. Gordon E, Integrative Neuroscience: Bringing Together Biological, Psychological and Clinical Models of the Human Brain, Harwood Academic, NY, 2000.
24. Gordon E, Integrative neuroscience and psychiatry, Neuropsychopharmacology 28:2-8, 2003.
25. Gordon E, Cooper N, Rennie C, Hermens D, Williams LM, Integrative neuroscience: The role of a standardized database, Clin EEG and Neurosci 36:64-75, 2005.
26. Gordon E, Liddell BJ, Brown KJ et al., Integrating objective gene-brain-behavior markers of psychiatric disorders, J Integr Neurosci 6:1-34, 2007.
27. Gray JA, The Psychology of Fear and Stress, Vol. 2, Cambridge University Press, New York, 1987.
28. Grieve SM, Clark CR, Williams LM, Peduto AS, Gordon E, Preservation of limbic and paralimbic structures in aging, Hum Brain Mapp 25 391-401, 2005.
29. Green MF, Olivieri B, Crawley JN, Penn DL, Silverstein S, Social cognition in schizophrenia: Recommendations from the measurement and treatment research to improve cognition in schizophrenia new approaches conference, Schizophr Bull 31:882-887, 2005.
30. Gross JJ, John OP, Individual differences in two emotion regulation processes: Implications for affect, relationships, and well-being, J Pers Soc Psychol 85:348-362, 2003.
31. Gur RC, Sara R, Hagendoorn M, Marom O, Hughett P, Macy L et al., A method for obtaining 3-dimensional facial expressions and its standardization for use in neurocognitive studies, J Neurosci Methods 115(2):137-143, 2002.
32. Halgren E, Marinkovic K, Neurophysiological networks integrating human emotions, in Gazzaniga M (ed.), The Cognitive Neurosciences. MIT Press, Cambridge MA, pp. 1137-1151, 1995.
33. Hariri AR, Mattay VS, Tessitore A, Kolachana B, Fera F, Goldman D et al., Serotonin transporter genetic variation and the response of the human amygdala, Science 297:400-403, 2002.
34. Izard CE, Human Emotions, Plenum Press, New York, 1977.
35. Keltikangas-Jarvinen L, Raikkonen K, Ekelund J, Peltonen L, Nature and nurture in novelty seeking, Mol Psychiatry 9(3):308-311, 2004.
36. Klimesch W, Binding principles in the theta frequency range, in Zimmer HD, Meeklinger A, Lindenberger U (eds.), Handbook of Binding and Memory, Oxford University Press, Oxford, pp. 115-144, 2006.
37. Kokare DM, Dandekar MP, Chopde CT, Subhedar N, Interaction between neuropeptide Y and alpha-melanocyte stimulating hormone in amygdala regulates anxiety in rats, Brain Res 1043:107-114, 2005.
38. Lamme VA, Roelfsema PR, The distinct modes of vision offered by feedforward and recurrent processing, Trends Neurosci 23 571-579, 2000.
39. Lane RD, Neural correlates of conscious emotional experience, in Lane RD, Nadel L, (eds.), Cognitive Neuroscience of Emotion, Oxford University Press, Oxford, UK, pp. 345-370, 2000.
40. Lang PJ, The motivational organization of emotion: Affect-Reflex connections, in Van-Goozen S, Van de Poll NE, Sergeant JA (eds.), Emotions: Essays on Emotion Theory, Erlbaum, Hillsdale NJ, pp. 61-93, 1994.
41. Le Doux J, The Emotional Brain, Phoenix, New York, 1996.
42. Lee KH, Williams LM, Breakspear M et al., Synchronous gamma activity: A review and contribution to an integrative neuroscience model of schizophrenia, Brain Res Rev 41:57-78, 2003.
43. Liddell BJ, Brown KJ, Kemp AH, Barton MJ, Das P, Peduto A, Gordon E, Williams LM, A direct brainstem-amygdala-cortical "alarm'system for subliminal signals of fear, Neuroimage 24:235-243, 2005.
44. Lim CL, Gordon E, Rennie C, Wright JJ, Bahramali H, Li WM, Clouston P, Morris JGL, Dynamics of SCR, EEG and ERP activity in an oddball paradigm with short interstimulus intervals, Psychophysiology 36 543-551, 1999.
45. Lyons DE, Santos LR, Keil FC, Reflections of other minds: How primate social cognition can inform the function of mirror neurons, Curr Opin Neurobiol 16:230-234, 2006.
46. Merckelbach H, van den Hout MA, Jansen A, van der Molen GM, Many stimuli are frightening, but some are more frightening than others: The contributions of preparedness, dangerousness, and unpredictability to making a stimulus fearful, J Psychopathol Behav Assess 10 355-366, 1998.
47. Oram MW, Perrett DI, The time course of neural responses discriminating between different views of the head and face, J Neurophysiol 68 70-84, 1992.
48. Panskepp J, Affective Neuroscience: The Foundations of Human and Animal Emotions, Oxford University Press, Oxford, 1998.
49. Paul RH, Gunstad J, Cooper N, Williams LM, Clark CR, Cohen RA, Lawrence JJ, Gordon E, Cross cultural assessment of neuropsychological performance and electrical brain function measures: Additional validation of an international brain database, Int J Neurosci 6 191-203, 2007.
50. Paul RH, Lawrence J, Williams LM, Clark CR, Cooper N, Gordon E, Preliminary validity of "IntegNeuro': A new computerized battery of neurocognitive tests, Int J Neurosci 115:1549-1567, 2005.
51. Plutchik R, A general psychoevolutionary theory of emotion, in R Plutchik, H Kellerman (eds.), Emotion: Theory, Research, and Experience: Vol. 1. Theories of Emotion, Academic Press, New York, pp. 3-33, 1980.
52. Pribram KH, McGuinness D, Arousal, activation and effort in the control of attention, Psychol Rev 82:116-149, 1975.
53. Robinson MD, Running from William James' bear: A review of preattentive mechanisms and their contributions to emotional experience, Cogn Emot 12:667-696, 1998.
54. Rodman HR et al., Afferent basis of visual response properties in area MT of the macaque, II, Effects of superior colliculus removal, J Neurosci 10: 1154-1164, 1990.
55. Rowe DL, Cooper NJ, Liddell BJ, Clark CR, Gordon E, Williams LM, Brain structure and brain function correlates of general and social cognition, J Integr Neurosci 6:35-74, 2007.
56. Rozin P, Royzman EB, Negativity bias, negativity dominance and contagion, Pers Soc Psychol Rev 5:296-320, 2001.
57. Ruchsow M, Spitzer M, Gröhn G, Keifer M, Error processing and impulsiveness in normals: Evidence from event-related potentials, Cogn Brain Res 24:317-325, 2005.
58. Savitz J, Solms M, Ramesar R, The molecular genetics of cognition: Dopamine, COMT and BDNF, Genes Brain Behav 5:311-328, 2006.
59. Scherer KR, What are emotions? And how can they be measured? Soc Sci Inf 44:695-729, 2005.
60. Schofield PRS, Williams LM, Paul RH, Gatt JM, Brown K, Luty A et al. Disturbances in task-relevant information processing associated with the brain-derived neurotrophic factor Va166Met polymorphism: Evidence from cognition, the P300 endophenotype and neuroirnaging, Biol Psychol (in press).
61. Schuschang H, Huang J, Wu Z, Li L, Glutamate and GABAB transmissions in lateral amygdala are involved in startle-like electromyographic (EMG) potentiation caused by activation of auditory thalamus, Neurosci Lett 374:113-118, 2005.
62. Sokolov EN, Boucsein W, A psychophysiological model of emotion space, Integr Physiol Behav Sci 35:81-119, 2000.
63. Sperling G, The information available in brief visual presentations, Psychol Monogr: General and Applied 74:1-30, 1960.
64. Thayer JF, Lane RD, A model of neurovisceral integration in emotion regulation and dysregulation, J Affect Disord 61:201-216, 2000.
65. Tomkins SS, Affect theory, in Scherer KR, Ekman P (eds.), Approaches to Emotion, Erlbaum, Hillsdale NJ, pp. 163-195, 1984.
66. Tovee MJ, How fast is the speed of thought? Curr Biol 4 1125-1127, 1994.
67. Tanaka K, Inferotemporal cortex and object vision, Anna Rev Neurosci 19:109-139, 1996.
68. Tsodyks M, Ariel A, Markram H, Synchrony generation in recurrent networks with frequency-dependent synapses, J Neurosci 20 1-5, 2000.
69. Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, Mazoyer B, Joliot M, Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain, Neuroimage 15:273-289, 2002.
70. Vitalis T, Fouquet C, Alvarez C, Seif I, Price D, Gaspar P, Cases O, Developmental expression of monoamine oxidases A and B in the central and peripheral nervous systems of the mouse, J Comp Neural 442 (4):331-347, 2002.
71. Vogel CI, Laucht M, Furtado EF, Becker K, Schmidt MH, Association of DRD4 exon III polymorphism with auditory P300 amplitude in 8-year-old children, J Neural Transm 113(12):1935-1941, 2006.
72. 158Met genotype on emotional recognition abilities in healthy men and women, J Int Neuropsychol Soc 13:1-7, 2007.
73. Whalen PJ, Kagan J, Cook RG, Davis FC, Kim H, Polis S, McLaren DG, Somerville LH, McLean AA, Maxwell JS, Johnstone T, Human amygdala responsivity to masked fearful eye whites, Science 306:2061, 2004.
74. Whitford TJ, Rennie CJ, Grieve SM et al., Brain maturation in adolescence: Concurrent changes in neuroanatomy and neurophysiology, Hum Brain Mapp 28:228-237, 2007.
75. Wild B, Erb M, Bartels M, Are emotions contagious? Evoked emotions while viewing emotionally expressive faces: Quality, quantity, time course and gender differences, Psychiatry Res 102:109-124, 2001.
76. Wilhelm K, Mitchell PB, Niven H, Finch A, Wedgwood L, Scimone A, Blair IP, Parker G, Schofield PR, Life events, first depression onset and the serotonin transporter gene, Br J Psychiatry 188:210-215, 2006.
77. Williams LM, An integrative neuroscience model of "significance" processing, J Int Neurosci 5:1-47, 2006.
78. Williams LM, Brown KJ, Palmer D, Liddell BJ, Kemp AIL Olivieri G, Peduto AS, Gordon E, The "mellow years": Neural basis of improving emotional stability over age, J Neurosci 26:6422-6430, 2006.
79. Williams LM, Das P, Liddell BJ, Kemp AH, Rennie CJ, Gordon E, Awareness for fear depends on mode of connectivity in amygdala pathways, J Neurosci 26:9264-9271, 2006.
80. Williams LM, Felmingham K, Kemp AH, Rennie C, Brown KJ, Bryant RA, Gordon E, Mapping frontal-limbic correlates of orienting to change detection, Neuroreport 18:197-202, 2007.
81. Williams LM, Gordon E, The dynamic organization of the emotional brain: Responsivity, stability and instability, Neuroscientist 13 349-370, 2007.
82. Williams LM, Kemp AH, Felmingham K, Liddell B, Palmer D, Bryant RA, The negativity bias to covert and overt signals of fear: Impact of anxiety and depressed mood, J Cogn Neurosci 19(10): 1595-1608, 2007.
83. Williams LM, Kuan SA, Gatt JM, Dobson-Stone C, Palmer D, Paul RH, Song L, Costa PT, Schofield PR, Gordon E, A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an Antisocial- Psychopathy Index. Neuropsychopharmacology (in revision).
84. Williams LM, Liddell BJ, Kemp AH, Bryant RA, Peduto AS, Meares RA, Gordon E, An amygdala-prefrontal dissociation of subliminal and supraliminal fear, Hum Brain Mapp 27:652-661, 2006.
85. Williams LM, Liddell BJ, Rathjen J, Brown KJ, Shevrin H, Gray JA, Phillips M, Young A, Gordon E, Mapping the time course of nonconscious and conscious perception of fear: An integration of central and peripheral measures, Hum Brain Mapp 21:64-74, 2004.
86. Williams LM, Mathersul D, Palmer DM, Gur RC, Gur RE, Gordon E, Explicit identification and implicit recognition of facial emotions: I, Age effects in males and females across 10 decades, J Clin Exp Neuropsychol in press, 2009.
87. Williams LM, Palmer, D, Liddell BJ, Song L, Gordon E, The "when" and "where" of perceiving signals of threat versus non-threat, Neuroimage 31:458-467, 2006.
88. Williams LM, Simms E, Clark CR, Paul RH, Rowe D, Gordon E, The test-retest reliability of a standardized neurophysiological and neuropsychological test battery: "NeuroMarker". Int J Neurosci 15:1605-1630, 2005.
89. Williams LM, Whitford TJ, Flynn G, Wong W, Liddell BJ, Silverstein S et al., General and social cognition in first episode schizophrenia: Identification of separable factors and prediction of functional outcome using the IntegNeuro test battery, Schizophr Res 99:182-191, 2008.
90. World Population Prospects, Volume II. Sex and Age. The Population Division, Department of Economic and Social Affairs, United Nations Secretariat, 1998.