Riboflavin-mediated cellular photoinhibition of cisplatin-induced oxidative DNA breakage in mice epidermal keratinocytes

Photodermatology Photoimmunology and Photomedicine

Volumn 24, Issue 6, 2008, Pages 301-307

  Husain, Eram ^a   Naseem, Imrana ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

Cisplatin; Comet assay; Photodynamic therapy; Reactive oxygen species; Riboflavin

Indexed keywords

CELL DNA; CISPLATIN; REACTIVE OXYGEN METABOLITE; RIBOFLAVIN;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA STRAND BREAKAGE; GENOTOXICITY; IRRADIATION; KERATINOCYTE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHOTOINHIBITION; PHOTOSENSITIZATION; PRIORITY JOURNAL;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CISPLATIN; CYTOPROTECTION; DNA DAMAGE; EPIDERMIS; KERATINOCYTES; MICE; MICE, INBRED BALB C; OXIDATION-REDUCTION; REACTIVE OXYGEN SPECIES; RIBOFLAVIN;

EID: 56349107394     PISSN: 09054383     EISSN: 16000781     Source Type: Journal    
DOI: 10.1111/j.1600-0781.2008.00380.x     Document Type: Article

References (54)

1. Loehrer PJ, Einhorn LH. Drugs five years later. Cisplatin. Ann Intern Med 1984; 100: 704-713.
2. Prestayko AW, D'Aoust JC, Issell BF, Crooke ST. Cisplatin (cis-diamminedichloroplatinum II). Cancer Treat Rev 1979; 6: 17-39.
3. Featherstone J, Dykes PJ, Marks R. The effect of platinum complexes on human skin cells in vivo and in vitro. Skin Pharmacol 1991; 4: 169-174.
4. Fichtinger-Schepman AM, van der Veer JL, den Hartog JH, Lohman PH, Reedijk J. Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: Formation, identification and quantitation. Biochemistry 1985; 24: 707-713.
5. Suo Z, Lippard SJ, Johnson KA. Single d(GpG) cis-diammineplatinum(II) adduct-induced inhibition of DNA polymerization. Biochemistry 1999; 38: 715-726.
6. Safirstein R, Winston J, Moel D, Dikman S, Gutterplan J. Cisplatin nephrotoxicity: Insights into mechanism. Int J Androl 1987; 10: 325-346.
7. Greggi Antunes LM, Darin JDC, Bianchi MD. Protective effects of vitamin C against cisplatin induced-nephrotoxicity and lipid peroxidation in adult rats: A dose-dependent study. Pharmacol Res 2000; 41: 405-411.
8. Kempf SR, Ivankovic S. Carcinogenic effect of cisplatin (cis-diammine-dichloroplatinum (II), CDDP) in BD IX rats. J Cancer Res Clin Oncol 1986; 111: 133-136.
9. Yoshida M, Fukuda A, Hara M, Terada A, Kitanaka Y, Owada S. Melatonin prevents the increase in hydroxyl radical spin trap adduct formation caused by the addition of cisplatin in vitro. Life Sci 2003; 72: 1773-1780.
10. Masuda H, Tanaka T, Takahama U. Cisplatin generates superoxide anion by interaction with DNA in a cell free system. Biochem Biophys Res Commun 1994; 203: 1175-1180.
11. Matsushima H, Yonemura K, Ohishi K, Hishida A. The role of oxygen free radicals in cisplatin-induced acute renal failure in rats. J Lab Clin Med 1998; 131: 518-526.
12. Nefic H. Anticlastogenic effect of vitamin C on cisplatin induced chromosome aberrations in human lymphocytes cultures. Mutat Res 2001; 498: 89-98.
13. Xiao T, Choudhary S, Xang W, Ansari NH, Salahudeen A. Possible involvement of oxidative stress in cisplatin induced apoptosis in LLC-PK1 cells. J Toxicol Environ Health 2003; 14: 469-479.
14. Massey V. The chemical and biological versatility of riboflavin. Biochem Soc Trans 2000; 28: 283-296.
15. Edwards MA, Silva E. Effect of visible light on selected enzymes, vitamins and amino acids. J Photochem Photobiol B: Biol 2001; 63: 126-131.
16. Naseem I, Ahmed MS, Bhat R, Hadi SM. Cu(II) dependent degradation of DNA by riboflavin. Food Chem Toxicol 1993; 31: 589-597.
17. Jazzar MM, Naseem I. Enhanced protein degradation by photoilluminated riboflavin in the presence of Cu(II). Biochem Mol Biol Int 1994; 34: 883-895.
18. Jazzar MM, Naseem I. Genotoxicity of photoilluminated riboflavin in the presence of Cu(II). Free Radic Biol Med 1996; 21: 7-14.
19. Cosa G. Photodegradation and photosensitization in pharmaceutical products. Assessing drug phototoxicity. Pure Appl Chem 2004; 76: 263-275.
20. Massad WA, Bertolotti SG, Romero M, Garcia NA. A kinetic study on the inhibitory action of sympathomimetic drugs towards photogenerated oxygen active species. The case of phenylephrine. J Photochem Photobiol B: Biol 2005; 80: 130-138.
21. Roy DK, Saha A, Mukherjee AK. Spectroscopic and thermodynamic study of charge transfer complex formation between cloxacillin sodium and riboflavin in aqueous ethanol media of varying composition. Spectrochim Acta A Mol Biomol Spectrosc 2006; 63: 694-699.
22. Fuchs J, Weber S, Kaufmann R. Genotoxic potential of porphyrin type photosensitizers with particular emphasis on 5-aminolevulinic acid: implications for clinical photodynamic therapy. Free Radic Biol Med 2000; 28: 537-548.
23. 2 mediated cellular photoinhibition of botulinum neurotoxin A. FEBS Lett 2005; 579: 5361-5364.
24. Reszka KJ, Denning GM, Britigan BE. Photosensitized oxidation and inactivation of pyocyanin, a virulence factor of Pseudomonas aeruginosa. Photochem Photobiol 2006; 82: 466-473.
25. Ouhtit A, Gorny A, Muller HK, Hill LL, Owen-Schaub L, Ananthaswamy HN. Loss of fas-ligand expression in mouse keratinocytes during UV carcinogenesis. Am J Pathol 2000; 157: 1975-1981.
26. Siemes C, Quast T, Kummer C, Wehner S, Kirfel G, Müller U, Herzog V. Keratinocytes from APP/APLP2-deficient mice are impaired in proliferation, adhesion and migration in vitro. Exp Cell Res 2006; 312: 1939-1949.
27. Singh NP, McCoy MT, Tice RR, Schneider EL. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 1988; 175: 184-191.
28. Keston AS, Brandt R. The fluorometric analysis of ultramicro quantities of hydrogen peroxide. Anal Biochem 1965; 11: 1-5.
29. Crow JP. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species. Nitric Oxide 1997; 1: 145-157.
30. Wang H, Joseph JA. Quantifying cellular oxidative stress by dichlorofluorescein assay using microplate reader. Free Radic Biol Med 1999; 27: 612-616.
31. Tice RR, Agurell E, Anderson D, et al. Single cell gel electrophoresis/ comet assay; guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 2000; 35: 206-221.
32. Fairbairn DW, Olive PL, O'Neill KL. The comet assay: A comprehensive review. Mutat Res 1995; 339: 37-59.
33. Ferguson LR, Pearson AE. The clinical use of mutagenic anticancer drugs. Mutat Res 1996; 355: 1-12.
34. Rosenberg B. Fundamental studies with cisplatin. Cancer 1985; 55: 2303-2316.
35. Blasiak J, Kowalik J. Protective action of vitamin C against DNA damage induced by selenium-cisplatin conjugate. Acta Biochim Pol 2001; 48: 233-240.
36. Auersperg N, Edelson MI, Mok SC, Johnson SW, Hamilton TC. The biology of ovarian cancer. Semin Oncol 1998; 25: 281-304.
37. Weijl NI, Cleton FJ, Osanto S. Free radicals and antioxidants in chemotherapy-induced toxicity. Cancer Treat Rev 1997; 23: 209-240.
38. Hovhannisyan GG, Haroutunyan TS, Arutyunyan RM. Evaluation of cisplatin-DNA crosslinks formation with UV-C application by the alkaline comet-assay. Exp Oncol 2004; 26: 240-242.
39. Jirsova K, Mandys V, Gispen WH, Bär PR. Cisplatin induced apoptosis in cultures of human Schwann cells. Neurosci Lett 2006; 392: 22-26.
40. Zamorano-Ponce E, Fernández J, Vargas G, Rivera P, Carballo MA. Protective activity of cedron (Aloysia triphyllia) infusion over genetic damage induced by cisplatin evaluated by the comet assay technique. Toxicol Lett 2004; 152: 85-90.
41. Mackay FS, Woods JA, Moseley H, et al. A photoactivated trans-diammine platinum complex as cytotoxic as cisplatin. Chemistry 2006; 12: 3155-3161.
42. Hartmann A, Speit G. Comparative investigations of the genotoxic effects of metals in the single cells gel (SCG) assay and the sister-chromatid exchange (SCE) test. Environ Mol Mutagen 1994; 23: 299-305.
43. Wozniak K, Czechowska A, Blasiak J. Cisplatin-evoked DNA fragmentation in normal and cancer cells and its modulation by free radical scavengers and the tyrosine kinase inhibitor STI 571. Chem Biol Interact 2005; 147: 309-318.
44. Clingen PH, Arlett CF, Hartley JA, Parris CN. Chemosensitivity of primary human fibroblasts with defective unhooking of DNA interstrand crosslinks. Exp Cell Res 2007; 313: 753-760.
45. Zempleni J, Mock DD. Proliferation of peripheral blood mononuclear cells increases riboflavin influx. Proc Soc Exp Biol Med 2000; 225: 72-79.
46. Zempleni J, Galloway JR, McCormick DB. Pharmacokinetics and utilization of orally and intravenously administered riboflavin in healthy humans. Am J Clin Nutr 1996; 63: 54-66.
47. Castillo C, Criado S, Diaz M, Garcia NA. Riboflavin as a sensitizer in the photodegradation of tetracyclines. Kinetics, mechanism and microbiological implications. Dyes Pigments 2007; 72: 78-184.
48. Ramu A, Mehta M, Liu J, Turyan I, Aleksic A. The riboflavin-mediated photooxidation of doxorubicin. Cancer Chemother Pharmacol 2000; 46: 449-458.
49. Yang X, Zhao X, Hwang H. Phototransformation of 2,4,6-trinitrotoluene: sensitized by riboflavin under different irradiation spectral range. J Hazard Mater 2007; 143: 271-276.
50. Massad W, Criado S, Bertolotti S, et al. Photodegradation of the herbicide Norflurazon sensitised by Riboflavin. A kinetic and mechanistic study. Chemosphere 2004; 57: 455-461.
51. Heelis PF. The photophysical and photochemical properties of flavins (isoalloxazines). Chem Soc Rev 1982; 11: 15-39.
52. Levy JG, Obochi M. New applications in photodynamic therapy. Introduction. Photochem Photobiol 1996; 64: 737-739.
53. Bonett R, Martinez G. Photobleaching of sensitizers used in photodynamic therapy. Tetrahedron 2001; 57: 9513-9547.
54. Huang Z. A review of progress in clinical photodynamic therapy. Technol Cancer Res Treat 2005; 4: 283-293.