메뉴 건너뛰기




Volumn 657, Issue 2, 2008, Pages 98-104

Naturally occurring chlorophyll derivatives inhibit aflatoxin B1-DNA adduct formation in hepatoma cells

Author keywords

Aflatoxin B1; Chlorophyll derivatives; Chlorophyllide; Glutathione S transferase; GST; Pheophorbide

Indexed keywords

AFLATOXIN B1; CHLOROPHYLL; CHLOROPHYLLIDE; CHLOROPHYLLIDE A; CHLOROPHYLLIDE B; GLUTATHIONE TRANSFERASE; PHEOPHORBIDE; PHEOPHORBIDE A; PHEOPHORBIDE B; UNCLASSIFIED DRUG;

EID: 56249117649     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2008.08.001     Document Type: Article
Times cited : (35)

References (38)
  • 1
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence
    • Block G., Patterson B., and Subar A. Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence. Nutr. Cancer 18 (1992) 1-29
    • (1992) Nutr. Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 2
    • 0030976823 scopus 로고    scopus 로고
    • Antigenotoxic activity of natural chlorophylls
    • Negishi T., Rai H., and Hayatsu H. Antigenotoxic activity of natural chlorophylls. Mutat. Res. 376 (1997) 97-100
    • (1997) Mutat. Res. , vol.376 , pp. 97-100
    • Negishi, T.1    Rai, H.2    Hayatsu, H.3
  • 3
    • 0018860177 scopus 로고
    • Antimutagenic activities of common vegetables and their chlorophyll content
    • Lai C.N., Butler M.A., and Matney T.S. Antimutagenic activities of common vegetables and their chlorophyll content. Mutat. Res. 77 (1980) 245-250
    • (1980) Mutat. Res. , vol.77 , pp. 245-250
    • Lai, C.N.1    Butler, M.A.2    Matney, T.S.3
  • 4
    • 0031927830 scopus 로고    scopus 로고
    • Chemoprotection by natural chlorophylls in vivo: inhibition of dibenzo[a,l]pyrene-DNA adducts in rainbow trout liver
    • Harttig U., and Bailey G.S. Chemoprotection by natural chlorophylls in vivo: inhibition of dibenzo[a,l]pyrene-DNA adducts in rainbow trout liver. Carcinogenesis 19 (1998) 1323-1326
    • (1998) Carcinogenesis , vol.19 , pp. 1323-1326
    • Harttig, U.1    Bailey, G.S.2
  • 5
    • 0025763615 scopus 로고
    • Chemopreventive properties of chlorophyllin: inhibition of aflatoxin B1 (AFB1)-DNA binding in vivo and anti-mutagenic activity against AFB1 and two heterocyclic amines in the Salmonella mutagenicity assay
    • Dashwood R.H., Breinholt V., and Bailey G.S. Chemopreventive properties of chlorophyllin: inhibition of aflatoxin B1 (AFB1)-DNA binding in vivo and anti-mutagenic activity against AFB1 and two heterocyclic amines in the Salmonella mutagenicity assay. Carcinogenesis 12 (1991) 939-942
    • (1991) Carcinogenesis , vol.12 , pp. 939-942
    • Dashwood, R.H.1    Breinholt, V.2    Bailey, G.S.3
  • 6
    • 0033566210 scopus 로고    scopus 로고
    • Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: an evaluation of reduced bioavailability vs. target organ protective mechanisms
    • Breinholt V., Arbogast D., Loveland P., Pereira C., Dashwood R., Hendricks J., and Bailey G. Chlorophyllin chemoprevention in trout initiated by aflatoxin B(1) bath treatment: an evaluation of reduced bioavailability vs. target organ protective mechanisms. Toxicol. Appl. Pharmacol. 158 (1999) 141-151
    • (1999) Toxicol. Appl. Pharmacol. , vol.158 , pp. 141-151
    • Breinholt, V.1    Arbogast, D.2    Loveland, P.3    Pereira, C.4    Dashwood, R.5    Hendricks, J.6    Bailey, G.7
  • 8
    • 0027312075 scopus 로고
    • Binding of polycyclic planar mutagens to chlorophyllin resulting in inhibition of the mutagenic activity
    • Arimoto S., Fukuoka S., Itome C., Nakano H., Rai H., and Hayatsu H. Binding of polycyclic planar mutagens to chlorophyllin resulting in inhibition of the mutagenic activity. Mutat. Res. 287 (1993) 293-305
    • (1993) Mutat. Res. , vol.287 , pp. 293-305
    • Arimoto, S.1    Fukuoka, S.2    Itome, C.3    Nakano, H.4    Rai, H.5    Hayatsu, H.6
  • 9
    • 16544376533 scopus 로고    scopus 로고
    • Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions
    • Williams J.H., Phillips T.D., Jolly P.E., Stiles J.K., Jolly C.M., and Aggarwal D. Human aflatoxicosis in developing countries: a review of toxicology, exposure, potential health consequences, and interventions. Am. J. Clin. Nutr. 80 (2004) 1106-1122
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 1106-1122
    • Williams, J.H.1    Phillips, T.D.2    Jolly, P.E.3    Stiles, J.K.4    Jolly, C.M.5    Aggarwal, D.6
  • 11
  • 12
    • 0020519324 scopus 로고
    • Base substitution mutations induced by metabolically activated aflatoxin B1
    • Foster P.L., Eisenstadt E., and Miller J.H. Base substitution mutations induced by metabolically activated aflatoxin B1. Proc. Natl. Acad. Sci. U. S. A. 80 (1983) 2695-2698
    • (1983) Proc. Natl. Acad. Sci. U. S. A. , vol.80 , pp. 2695-2698
    • Foster, P.L.1    Eisenstadt, E.2    Miller, J.H.3
  • 14
    • 0026639135 scopus 로고
    • Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide
    • Hayes J.D., Judah D.J., Neal G.E., and Nguyen T. Molecular cloning and heterologous expression of a cDNA encoding a mouse glutathione S-transferase Yc subunit possessing high catalytic activity for aflatoxin B1-8,9-epoxide. Biochem. J. 285 1 (1992) 173-180
    • (1992) Biochem. J. , vol.285 , Issue.1 , pp. 173-180
    • Hayes, J.D.1    Judah, D.J.2    Neal, G.E.3    Nguyen, T.4
  • 15
    • 0034651240 scopus 로고    scopus 로고
    • Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver
    • Kelly V.P., Ellis E.M., Manson M.M., Chanas S.A., Moffat G.J., McLeod R., Judah D.J., Neal G.E., and Hayes J.D. Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver. Cancer Res. 60 (2000) 957-969
    • (2000) Cancer Res. , vol.60 , pp. 957-969
    • Kelly, V.P.1    Ellis, E.M.2    Manson, M.M.3    Chanas, S.A.4    Moffat, G.J.5    McLeod, R.6    Judah, D.J.7    Neal, G.E.8    Hayes, J.D.9
  • 16
    • 0033935601 scopus 로고    scopus 로고
    • GSTs are responsible for aflatoxin B(1)-8,9-epoxide-conjugating activity in the nonhuman primate Macaca fascicularis liver
    • Wang C., Bammler T.K., Guo Y., Kelly E.J., Eaton D.L., and Mu-class. GSTs are responsible for aflatoxin B(1)-8,9-epoxide-conjugating activity in the nonhuman primate Macaca fascicularis liver. Toxicol. Sci. 56 (2000) 26-36
    • (2000) Toxicol. Sci. , vol.56 , pp. 26-36
    • Wang, C.1    Bammler, T.K.2    Guo, Y.3    Kelly, E.J.4    Eaton, D.L.5    Mu-class6
  • 17
    • 33847162510 scopus 로고    scopus 로고
    • Methods for the determination of the chlorophylls and their derivatives
    • Yang C.M., Chang K.W., Yin M.H., and Huang H.M. Methods for the determination of the chlorophylls and their derivatives. Taiwania 43 (1998) 116-122
    • (1998) Taiwania , vol.43 , pp. 116-122
    • Yang, C.M.1    Chang, K.W.2    Yin, M.H.3    Huang, H.M.4
  • 18
    • 0342470673 scopus 로고    scopus 로고
    • High-performance liquid chromatographic screening of chlorophyll derivatives produced during fruit storage
    • Almela L., Fernandez-Lopez J.A., and Roca M.J. High-performance liquid chromatographic screening of chlorophyll derivatives produced during fruit storage. J. Chromatogr. A 870 (2000) 483-489
    • (2000) J. Chromatogr. A , vol.870 , pp. 483-489
    • Almela, L.1    Fernandez-Lopez, J.A.2    Roca, M.J.3
  • 19
    • 0023655085 scopus 로고
    • Mechanism of cytotoxicity of aflatoxin B1: role of cytochrome P1-450
    • Karenlampi S.O. Mechanism of cytotoxicity of aflatoxin B1: role of cytochrome P1-450. Biochem. Biophys. Res. Commun. 145 (1987) 854-860
    • (1987) Biochem. Biophys. Res. Commun. , vol.145 , pp. 854-860
    • Karenlampi, S.O.1
  • 20
    • 0025899234 scopus 로고
    • Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture
    • Cory A.H., Owen T.C., Barltrop J.A., and Cory J.G. Use of an aqueous soluble tetrazolium/formazan assay for cell growth assays in culture. Cancer Commun. 3 (1991) 207-212
    • (1991) Cancer Commun. , vol.3 , pp. 207-212
    • Cory, A.H.1    Owen, T.C.2    Barltrop, J.A.3    Cory, J.G.4
  • 21
    • 0023734654 scopus 로고
    • Immunological detection of aflatoxin B1-DNA adducts formed in vivo
    • Hsieh L.L., Hsu S.W., Chen D.S., and Santella R.M. Immunological detection of aflatoxin B1-DNA adducts formed in vivo. Cancer Res. 48 (1988) 6328-6331
    • (1988) Cancer Res. , vol.48 , pp. 6328-6331
    • Hsieh, L.L.1    Hsu, S.W.2    Chen, D.S.3    Santella, R.M.4
  • 22
    • 0016275313 scopus 로고
    • Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
    • (1974) J. Biol. Chem. , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 23
    • 0024712069 scopus 로고
    • Generation of free radicals by photoexcitation of pheophorbide alpha, haematoporphyrin and protoporphyrin
    • Haseloff R.F., Ebert B., and Roeder B. Generation of free radicals by photoexcitation of pheophorbide alpha, haematoporphyrin and protoporphyrin. J. Photochem. Photobiol. B 3 (1989) 593-602
    • (1989) J. Photochem. Photobiol. B , vol.3 , pp. 593-602
    • Haseloff, R.F.1    Ebert, B.2    Roeder, B.3
  • 26
    • 0028050207 scopus 로고
    • Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo[a]pyrene: studies of enzyme inhibition, molecular complex formation and degradation of the ultimate carcinogen
    • Tachino N., Guo D., Dashwood W.M., Yamane S., Larsen R., and Dashwood R. Mechanisms of the in vitro antimutagenic action of chlorophyllin against benzo[a]pyrene: studies of enzyme inhibition, molecular complex formation and degradation of the ultimate carcinogen. Mutat. Res. 308 (1994) 191-203
    • (1994) Mutat. Res. , vol.308 , pp. 191-203
    • Tachino, N.1    Guo, D.2    Dashwood, W.M.3    Yamane, S.4    Larsen, R.5    Dashwood, R.6
  • 27
    • 0029063179 scopus 로고
    • Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: complex formation with the carcinogen
    • Breinholt V., Schimerlik M., Dashwood R., and Bailey G. Mechanisms of chlorophyllin anticarcinogenesis against aflatoxin B1: complex formation with the carcinogen. Chem. Res. Toxicol. 8 (1995) 506-514
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 506-514
    • Breinholt, V.1    Schimerlik, M.2    Dashwood, R.3    Bailey, G.4
  • 28
    • 0024587561 scopus 로고
    • Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2)
    • Negishi T., Arimoto S., Nishizaki C., and Hayatsu H. Inhibitory effect of chlorophyll on the genotoxicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2). Carcinogenesis 10 (1989) 145-149
    • (1989) Carcinogenesis , vol.10 , pp. 145-149
    • Negishi, T.1    Arimoto, S.2    Nishizaki, C.3    Hayatsu, H.4
  • 30
    • 0022068393 scopus 로고
    • Basic study for cancer therapy with porphyrin derivatives and pheophorbide derivatives
    • Hayashi H., Nakajima S., and Samejima N. Basic study for cancer therapy with porphyrin derivatives and pheophorbide derivatives. Hokkaido Igaku Zasshi 60 (1985) 391-403
    • (1985) Hokkaido Igaku Zasshi , vol.60 , pp. 391-403
    • Hayashi, H.1    Nakajima, S.2    Samejima, N.3
  • 31
    • 0032832529 scopus 로고    scopus 로고
    • Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth
    • Chernomorsky S., Segelman A., and Poretz R.D. Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth. Teratogen. Carcinogen. Mutagen. 19 (1999) 313-322
    • (1999) Teratogen. Carcinogen. Mutagen. , vol.19 , pp. 313-322
    • Chernomorsky, S.1    Segelman, A.2    Poretz, R.D.3
  • 32
    • 0037518157 scopus 로고    scopus 로고
    • In vitro and in vivo efficacy of photofrin and pheophorbide a, a bacteriochlorin, in photodynamic therapy of colonic cancer cells
    • Hajri A., Wack S., Meyer C., Smith M.K., Leberquier C., Kedinger M., and Aprahamian M. In vitro and in vivo efficacy of photofrin and pheophorbide a, a bacteriochlorin, in photodynamic therapy of colonic cancer cells. Photochem. Photobiol. 75 (2002) 140-148
    • (2002) Photochem. Photobiol. , vol.75 , pp. 140-148
    • Hajri, A.1    Wack, S.2    Meyer, C.3    Smith, M.K.4    Leberquier, C.5    Kedinger, M.6    Aprahamian, M.7
  • 33
    • 33751081806 scopus 로고    scopus 로고
    • Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma
    • Tang P.M., Chan J.Y., Au S.W., Kong S.K., Tsui S.K., Waye M.M., Mak T.C., Fong W.P., and Fung K.P. Pheophorbide a, an active compound isolated from Scutellaria barbata, possesses photodynamic activities by inducing apoptosis in human hepatocellular carcinoma. Cancer Biol. Ther. 5 (2006) 1111-1116
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 1111-1116
    • Tang, P.M.1    Chan, J.Y.2    Au, S.W.3    Kong, S.K.4    Tsui, S.K.5    Waye, M.M.6    Mak, T.C.7    Fong, W.P.8    Fung, K.P.9
  • 34
    • 3442890261 scopus 로고    scopus 로고
    • Inactivation of mitochondrial electron transport by photosensitization of a pheophorbide a derivative
    • Kim C.S., Lee C.H., Lee P.H., and Han S. Inactivation of mitochondrial electron transport by photosensitization of a pheophorbide a derivative. Mol. Cells 17 (2004) 347-352
    • (2004) Mol. Cells , vol.17 , pp. 347-352
    • Kim, C.S.1    Lee, C.H.2    Lee, P.H.3    Han, S.4
  • 35
    • 29744441900 scopus 로고    scopus 로고
    • Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk
    • van Herwaarden A.E., Wagenaar E., Karnekamp B., Merino G., Jonker J.W., and Schinkel A.H. Breast cancer resistance protein (Bcrp1/Abcg2) reduces systemic exposure of the dietary carcinogens aflatoxin B1, IQ and Trp-P-1 but also mediates their secretion into breast milk. Carcinogenesis 27 (2006) 123-130
    • (2006) Carcinogenesis , vol.27 , pp. 123-130
    • van Herwaarden, A.E.1    Wagenaar, E.2    Karnekamp, B.3    Merino, G.4    Jonker, J.W.5    Schinkel, A.H.6
  • 36
    • 22844437903 scopus 로고    scopus 로고
    • Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes
    • Fahey J.W., Stephenson K.K., Dinkova-Kostova A.T., Egner P.A., Kensler T.W., and Talalay P. Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes. Carcinogenesis 26 (2005) 1247-1255
    • (2005) Carcinogenesis , vol.26 , pp. 1247-1255
    • Fahey, J.W.1    Stephenson, K.K.2    Dinkova-Kostova, A.T.3    Egner, P.A.4    Kensler, T.W.5    Talalay, P.6
  • 37
    • 8944225027 scopus 로고    scopus 로고
    • Modulatory influence of chlorophyllin on the mouse skin papillomagenesis and xenobiotic detoxication system
    • Singh A., Singh S.P., and Bamezai R. Modulatory influence of chlorophyllin on the mouse skin papillomagenesis and xenobiotic detoxication system. Carcinogenesis 17 (1996) 1459-1463
    • (1996) Carcinogenesis , vol.17 , pp. 1459-1463
    • Singh, A.1    Singh, S.P.2    Bamezai, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.