Involvement of ORL1 receptor and ERK kinase in the orphanin FQ-induced nociception in the nucleus accumbens of rats

Regulatory Peptides

Volumn 151, Issue 1-3, 2008, Pages 43-47

  Chen, Li Ying ^a   Huang, Jia Xin ^a   Yu, Long Chuan ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

ERK kinase; Hindpaw withdrawal latency; Nociception; Nucleus accumbens (NAc); Opioid receptor like (ORL1) receptor; Orphanin FQ (OFQ)

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; MITOGEN ACTIVATED PROTEIN KINASE; NOCICEPTIN; OPIATE RECEPTOR; OPIOID RECEPTOR LIKE RECEPTOR 1; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MALE; MECHANICAL STIMULATION; NOCICEPTION; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; THERMAL STIMULATION;

ANIMALS; BUTADIENES; MALE; MAP KINASE SIGNALING SYSTEM; NITRILES; NOCICEPTORS; NUCLEUS ACCUMBENS; OPIOID PEPTIDES; PAIN MEASUREMENT; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; RECEPTORS, OPIOID;

RATTUS;

EID: 56249093785     PISSN: 01670115     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.regpep.2008.06.001     Document Type: Article

References (29)

1. Meunier J.C., Mollereau C., Toll L., Suaudeau C., Moisand C., Alvinerie P., Butour J.L., Guillemot J.C., Ferrara P., Monsarrat B., et al. Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor. Nature 377 (1995) 532-535
2. Reinscheid R.K., Nothacker H.P., Bourson A., Ardati A., Henningsen R.A., Bunzow J.R., Grandy D.K., Langen H., Monsma Jr. F.J., Civelli O., and Orphanin F.Q. A neuropeptide that activates an opioidlike G protein-coupled receptor. Science 270 (1995) 792-794
3. Neal C.R., Mansour Jr. A., Reinscheid R., Nothacker H.P., Civelli O., and Watson Jr. S.J. Localization of orphanin FQ (nociceptin) peptide and messenger RNA in the central nervous system of the rat. J Comp Neurol 406 (1999) 503-547
4. Mogil J.S., and Pasternak G.W. The molecular and behavioral pharmacology of the orphanin FQ/nociceptin peptide and receptor family. Pharmacol Rev 53 (2001) 381-415
5. Bytner B., Huang Y.H., Yu L.C., Lundeberg T., Nylander I., and Rosen A. Nociceptin/orphanin FQ into the rat periaqueductal gray decreases the withdrawal latency to heat and loading, an effect reversed by (Nphe(1))nociceptin(1-13)NH(2). Brain Res 922 (2001) 118-124
6. Li N., Wei S.Y., Yu L.C., Moriyama K., Mitchell J., and Palmer P.P. Role of nociceptin in the modulation of nociception in the arcuate nucleus of rats. Brain Res 1025 (2004) 67-74
7. Calo G., Guerrini R., Bigoni R., Rizzi A., Marzola G., Okawa H., Bianchi C., Lambert D.G., Salvadori S., and Regoli D. Characterization of [Nphe(1)]nociceptin(1-13)NH(2), a new selective nociceptin receptor antagonist. Br J Pharmacol 129 (2000) 1183-1193
8. Li N., Lundeberg T., and Yu L.C. Involvement of CGRP and CGRP1 receptor in nociception in the nucleus accumbens of rats. Brain Res 901 (2001) 161-166
9. Xiong W., and Yu L.C. Involvements of mu- and kappa-opioid receptors in morphine-induced antinociception in the nucleus accumbens of rats. Neurosci Lett 399 (2006) 167-170
10. Gu X.L., and Yu L.C. Involvement of opioid receptors in oxytocin-induced antinociception in the nucleus accumbens of rats. J Pain 8 (2007) 85-90
11. Millan M.J., Audinot V., Honore P., Bervoets K., Veiga S., and Brocco M. Blockade of NMDA receptors in the nucleus accumbens elicits spontaneous tail-flicks in rats. Eur J Pharmacol 388 (2000) 37-47
12. Xiong W., and Yu L.C. Involvement of endogenous cholecystokinin in morphine tolerance in the nucleus accumbens of rats. Behav Brain Res 173 (2006) 116-121
13. Moran T.D., Abdulla F.A., and Smith P.A. Cellular neurophysiological actions of nociceptin/orphanin FQ. Peptides 21 (2000) 969-976
14. Lou L.G., Zhang Z., Ma L., and Pei G. Nociceptin/orphanin FQ activates mitogen-activated protein kinase in Chinese hamster ovary cells expressing opioid receptor-like receptor. J Neurochem 70 (1998) 1316-1322
15. Kyosseva S.V. Mitogen-activated protein kinase signaling. Int Rev Neurobiol 59 (2004) 201-220
16. Ma W., and Quirion R. The ERK/MAPK pathway, as a target for the treatment of neuropathic pain. Expert Opin Ther Targets 9 (2005) 699-713
17. Obata K., Yamanaka H., Dai Y., Mizushima T., Fukuoka T., Tokunaga A., and Noguchi K. Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats. Eur J Neurosci 20 (2004) 2881-2895
18. Zimmermann M. Ethical guidelines for investigations of experimental pain in conscious animals. Pain 16 (1983) 109-110
19. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates (1986), Academic Press, Sydney
20. Li J.J., Zhou X., and Yu L.C. Involvement of neuropeptide Y and Y1 receptor in antinociception in the arcuate nucleus of hypothalamus, an immunohistochemical and pharmacological study in intact rats and rats with inflammation. Pain 118 (2005) 232-242
21. Ko M.C., Wei H., Woods J.H., and Kennedy R.T. Effects of intrathecally administered nociceptin/orphanin FQ in monkeys: behavioral and mass spectrometric studies. J Pharmacol Exp Ther 318 (2006) 1257-1264
22. Lu J.T., Huang Y.H., Palmer P.P., Xie G.X., Gabriel A., Grond S., and Yu L.C. Blockade effects of (Nphe1)Nociceptin(1-13)-NH(2) on anti-nociception induced by intrathecal administration of nociceptin in rats. Regul Pept 101 (2001) 81-85
23. Mogil J.S., Grisel J.E., Zhangs G., Belknap J.K., and Grandy D.K. Functional antagonism of mu-, delta- and kappa-opioid antinociception by orphanin FQ. Neurosci Lett 213 (1996) 131-134
24. Rizzi A., Nazzaro C., Marzola G.G., Zucchini S., Trapella C., Guerrini R., Zeilhofer H.U., Regoli D., and Calo G. Endogenous nociceptin/orphanin FQ signalling produces opposite spinal antinociceptive and supraspinal pronociceptive effects in the mouse formalin test: pharmacological and genetic evidences. Pain 124 (2006) 100-108
25. Ross J., and Armstead W.M. Nociceptin/OFQ activates ERK and JNK but not p38 MAPK to impair prostaglandin cerebrovasodilation after brain injury. Brain Res 1054 (2005) 95-102
26. Aley K.O., Martin A., McMahon T., Mok J., Levine J.D., and Messing R.O. Nociceptor sensitization by extracellular signal-regulated kinases. J Neurosci 21 (2001) 6933-6939
27. Cruz C.D., Neto F.L., Castro-Lopes J., McMahon S.B., and Cruz F. Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats. Pain 116 (2005) 411-419
28. Dai Y., Iwata K., Fukuoka T., Kondo E., Tokunaga A., Yamanaka H., Tachibana T., Liu Y., and Noguchi K. Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization. J Neurosci 22 (2002) 7737-7745
29. Choi S.S., Seo Y.J., Kwon M.S., Shim E.J., Lee J.Y., Ham Y.O., Park S.H., and Suh H.W. Involvement of phosphorylated extracellular signal-regulated kinase in the mouse substance P pain model. Mol Brain Res 137 (2005) 152-158