Nimodipine prior to alcohol withdrawal prevents memory deficits during the abstinence phase

Neuroscience

Volumn 157, Issue 2, 2008, Pages 376-384

  Brooks, S P ^a   Croft, A P ^b   Norman, G ^c   Shaw, S G ^d   Little, H J ^e  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

^d UNIVERSITY OF BERN   (Switzerland)

^e ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

alcohol; calcium; cognition; memory; nimodipine

Indexed keywords

GLUCOCORTICOID; NIMODIPINE;

ALCOHOL CONSUMPTION; ALCOHOL WITHDRAWAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; MALE; MAZE TEST; MEMORY; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPEATED DRUG DOSE; SINGLE DRUG DOSE;

ALCOHOL-INDUCED DISORDERS; ALCOHOLS; ANALYSIS OF VARIANCE; ANIMALS; BODY WEIGHT; BRAIN; CALCIUM CHANNEL BLOCKERS; CORTICOSTERONE; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; MALE; MEMORY DISORDERS; NEUROPSYCHOLOGICAL TESTS; NIMODIPINE; RATS; SUBSTANCE WITHDRAWAL SYNDROME;

EID: 56149126347     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.09.010     Document Type: Article

References (85)

1. Bates M.E., Bowdon S.C., and Barry D. Neurocognitive impairment associated with alcohol use disorders: implications for treatment. Exp Clin Psychopharmacol 10 (2002) 193-212
2. Bouchenafa O., and Littleton J.M. Expression of c-Fos protein immunoreactivity in rat brain during ethanol withdrawal is prevented by nifedipine. Alcohol 15 (1998) 71-76
3. Brooks S.P., Hennebry G., McAlpin G., Norman G., and Little H.J. Nimodipine prevents the effects of ethanol in tests of memory. Neuropharmacology 42 (2002) 577-585
4. Carroll B.J., Heath B., and Jarret D.B. Corticosteroids in brain tissue. Endocrinology 97 (1975) 290-300
5. Ciesielski K.T., Waldorf A.V., and Jung R.E. Anterior brain deficits in chronic alcoholism: Cause or effect?. J Nerv Ment Dis 183 (1995) 756-+761
6. Dachir S., Kadar T., Robinzon B., and Levy A. Nimodipine's protection against corticosterone-induced morphological changes in the hippocampus of young rats. Brain Res 748 (1997) 175-183
7. Dahchour A., and de Witte P. Excitatory and inhibitory amino acid changes during repeated episodes of ethanol withdrawal: an in vivo dialysis study. Eur J Pharmacol 459 (2003) 171-178
8. Dhabhar F.S., Miller A.H., McEwan B.S., and Spencer R.S. Differential activation of adrenal steroid receptors in neural and immune tissue of Sprague-Dawley, Fischer and Lewis rats. J Neuroimmunol 56 (1995) 77-90
9. Diez J.A., Sze P.Y., and Ginsburg B.E. Postnatal development of mouse plasma and brain corticosterone levels: new findings contingent upon the use of a competitive protein-binding assay. Endocrinology 98 (1976) 1434-1442
10. Di Sclafani V., Ezekiel F., Meyerhof D.J., Mackay S., Dillon W.P., Weiner M.W., and Fein G. Brain atrophy and cognitive function in older abstinent alcoholic men. Alcohol Clin Exp Res 19 (1995) 1121-1126
11. Dolin S.J., and Little H.J. Are changes in neuronal calcium channels involved in ethanol tolerance?. J Pharmacol Exp Ther 250 (1989) 985-991
12. Dolin S.J., Little H.J., Hudspith M.J., Pagonis C., and Littleton J.M. Increased dihydropyridine-sensitive calcium channels in rat brain may underlie ethanol physical dependence. Neuropharmacology 26 (1987) 275-279
13. Duka T., Townsend J.M., Collier K., and Stephens D.N. Impairment in cognitive functions after multiple detoxifications in alcoholic inpatients. Alcohol Clin Exp Res 27 (2003) 1563-1572
14. Durand D., and Carlen P.L. Decreased neuronal inhibition in vitro after long-term administration of ethanol. Science 224 (1984) 1359-1361
15. Engel J.A., Fahlke C., Hulthe P., Hard E., Johannessen K., Snape B., and Svensson L. Biochemical and behavioural evidence for an interaction between ethanol and calcium channel antagonists. J Neural Transm 74 (1988) 181-193
16. Ennaceur A., and Delacour J. A new one-trial test for neurobiological studies of memory in rats. 1. Behavioral data. Behav Brain Res 31 (1988) 47-59
17. Fadda F., and Rossetti Z.L. Chronic ethanol consumption: from neuroadaptation to neurodegeneration. Prog Neurobiol 55 (1998) 1-47
18. Farr S.A., Scherrer J.F., Banks W.A., Flood J.F., and Morley J.E. Chronic ethanol consumption impairs learning and memory after cessation of ethanol. Alcohol Clin Exp Res 29 (2005) 971-982
19. 2+ channel subtypes expressed in Xenopus oocytes. J Pharmacol Exp Ther 291 (1999) 464-473
20. Graef E.A., Mermelstein P.G., Stankunas K., Neilson J.R., and Deisseroth K. L-type calcium channels and GSK03 regulate the activity of NF-ATc4 in hippocampal neurons. Nature 401 (1999) 703-708
21. Harkany T., Dijkstra I.M., Oosterlink B.J., Horvath K.M., Abraham I., Keijser J., Van der Zee E.A., and Luiten P.G.M. Increased amyloid precursor protein expression and serotonergic sprouting following excitotoxic lesion of the rat magnocellular nucleus basalis: neuroprotection by calcium antagonist, nimodipine. Neuroscience 101 (2000) 101-114
22. Harper C., Dixon G., Sheedy D., and Garrick T. Neuropathological alterations in alcoholic brains. Studies arising from the New South Wales Tissue Resource Centre. Prog Neuropsychopharmacol Biol Psychiatry 27 (2003) 951-961
23. Hernandez-Lopez S., Barga J., Surmier D.J., Reyes A., and Gallarraga E. D1 receptor activation enhances evoked discharge in neostriatal medium spiny neurons by modulating an L-type calcium conductance. J Neurosci 17 (1997) 3334-3342
24. Hoffmeister F., Benz U., Heise A., Krause H.P., and Neuser V. Behavioral effects of nimodipine. Arzneimittelforschung 32 (1982) 347-360
25. Ihara H., Berrios G.E., and London M. Group and case study of the dysexecutive syndrome in alcoholism without amnesia. J Neurol Neurosurg Psychiatry 68 (2000) 731-737
26. Irle E., and Markowitsch H.J. Widespread neuroanatomical damage and learning deficits following chronic alcohol consumption or vitamin B1 (thiamine) deficiency in rats. Behav Brain Res 9 (1983) 277-294
27. Izquierdo I. Nimodipine and the recovery of memory. Trends Pharmacol Sci 11 (1990) 309-310
28. Karst H., Nair S., Velzing E., Rumff-van Essen L., Slagter E., Shinnick-Gallagher P., and Joels M. Glucocorticoids alter calcium conductances and calcium channel subunit expressions in basolateral amygdala neurons. Eur J Neurosci 16 (2002) 1083-1089
29. Knapp D.J., and Pohrecky L.A. An air-puff stimulus method for elicitation of ultrasonic vocalizations in rats. J Neurosci Methods 62 (1995) 1-5
30. Kril J.J., Halliday G.M., Svoboda M.D., and Cartright H. The cerebral cortex is damaged in chronic alcoholics. Neuroscience 79 (1997) 983-998
31. Kubista H., Mafra R.A., Chong Y., Nicholson G.M., Beirao P.S.L., Cruz J.S., Boehm S., Nentwig W., and Kuhn-Nentwig L. CSTX-1, a toxin from the venom of the hunting spider Cupiennius salei, is a selective blocker of L-type calcium channels in mammalian neurons. Neuropharmacology 52 (2007) 1650-1662
32. Kuzmin A., Semenova S., Zvartau E., and De Vry J. Effects of calcium channel blockade on intravenous self-administration of ethanol in rats. Eur Neuropsychopharmacol 9 (1999) 197-203
33. Lieber C.S., and DeCarli L.M. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol 24 (1989) 197-211
34. Little H.J., Dolin S.J., and Halsey M.J. Calcium channel antagonists decrease the ethanol withdrawal syndrome. Life Sci 39 (1986) 2059-2065
35. Little H.J., Croft A.P., O'Callaghan M.J., Brooks S.P., Wang G., and Shaw S.G. Selective increases in regional brain glucocorticoid: a novel effect of chronic alcohol. Neuroscience (2008) in press
36. Littleton J.M., Little H.J., and Whittington M.A. Effects of dihydropyridine calcium channel antagonists in ethanol withdrawal: doses required, stereospecificity and actions of Bay K 8644. Psychopharmacology 100 (1990) 387-392
37. Lukoyanov N.V., and Paula-Barbosa M.M. Memantine, but not dizocilpine, ameliorates cognitive deficits in adult rats withdrawn from chronic ingestion of alcohol. Neurosci Lett 309 (2001) 45-48
38. Lukoyanov N.V., Madeira M.D., and PaulaBarbosa M.M. Behavioral and neuroanatomical consequences of chronic ethanol intake and withdrawal. Physiol Behav 66 (1999) 337-346
39. McHugh S.B., Niewoehner B., Rawlins J.N.P., and Bannerman D.M. Dorsal hippocampal N-methyl-D-aspartate receptors underlie spatial working memory performance during non-matching to place testing on the T-maze. Behav Brain Res 186 (2008) 41-47
40. Meaney M.J., Aitkin D.H., Sharma S., and Viau V. Basal ACTH, corticosterone and corticosterone-binding globulin levels over the diurnal cycle and age-related changes in hippocampal type I and type II corticosteroid receptor binding capacity in young and aged handled and non-handled rats. Neuroendocrinology 55 (1992) 204-213
41. Messing R., Carpenter C.L., Diamond I., and Greenburg D.A. Ethanol regulates calcium channels in clonal neural cells. Proc Natl Acad Sci U S A 83 (1986) 6213-6215
42. 2+ channel antagonists on morphine analgesia, tolerance and dependence, and on blood pressure in the rat. Eur J Pharmacol 352 (1998) 189-197
43. Misra R.P., Bonni A., Rivera V.M., Sheng M., and Greenberg M. L-type voltage-sensitive calcium-channel activation stimulates gene-expression by a serum response factor-dependent pathway. J Biol Chem 269 (1994) 25483-25493
44. B transmission, during withdrawal from chronic ethanol treatment. J Pharmacol Exp Ther 274 (1995) 1035-1041
45. Murphy T.H., Worley P.F., and Baraban J.M. L-type voltage-sensitive calcium channels mediate synaptic activation of immediate early genes. Neuron 7 (1991) 625-635
46. Noel X., Van der Linden M., Schmidt N., Sferrazza R., Hanak C., Le Bon O., De Mol J., Kornreich C., Pelc I., and Verbanck P. Supervisory attentional system in nonamnesic alcoholic men. Arch Gen Psychiatry 58 (2001) 1152-1158
47. Noel X., Sferrazza R., Van der Linden M., Paternot J., Verhas M., Hanak C., Pelc I., and Verbanck P. Contribution of frontal cerebral blood flow measured by Tc-99m-bicisate spect and executive function deficits to predicting treatment outcome in alcohol-dependent patients. Alcohol Alcohol 37 (2002) 347-354
48. Norman G., Brooks S.P., Hennebry G.M., Eacott M.J., and Little H.J. Nimodipine prevents scopolamine-induced impairments in object recognition. J Psychopharmacol 16 (2002) 153-161
49. Palmer G.C., Stagnitto M.L., Ray R.K., Knowles M.A., Harvey R., and Garske G.E. Anticonvulsant properties of calcium channel blockers in mice: N-methyl-DL-aspartate- and Bay K 8644-induced convulsions are potently blocked by the dihydropyridines. Epilepsia 34 (1993) 372-380
50. Pucilowski O., Rezvani A.H., and Janowski D.S. Suppression of alcohol and saccharin preferences in rats by a novel Ca channel inhibitor, Goe 5438. Psychopharmacology 107 (1992) 447-452
51. Quevedo J., Vianna M., Daroit D., Born A.G., Kuyven C.R., Roesler R., and Quillfeldt J.A. L-type voltage-dependent calcium channel blocker nifedipine enhances memory retention when infused into the hippocampus. Neurobiol Mem Learn 69 (1998) 320-325
52. Rajan V., Edward C.R.W., and Seckl J.R. 11β-Hydroxysteroid dehydrogenase in cultured hippocampal cells reactivates inert 11-dehydrocorticosterone, potentiating neurotoxicity. J Neurosci 16 (1996) 65-70
53. Reimer A.R., and Martiniverson M.T. Nimodipine and haloperidol attenuate behavioral sensitization to cocaine but only nimodipine blocks the establishment of conditioned locomotion induced by cocaine. Psychopharmacology 113 (1994) 404-410
54. Ripley T.L., Butterworth A.R., and Little H.J. Nitrendipine prevents the decrease caused by chronic ethanol intake in the maintenance of tetanic long-term potentiation. Exp Brain Res 103 (1995) 1-8
55. Rossetti Z.L., Isola D., De Vry J., and Fadda F. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology 38 (1999) 1361-1369
56. Sakai R.R., Monder C., and McEwen B.S. Immunocytochemical localization of 11beta-hydroxysteroid dehydrogenase in hippocampus and other brain regions of the rat. J Neuroendocrinol 4 (1999) 101-106
57. SanchezSanted F., deBruin J.P.C., Heinsbroek R.P.W., and Verwer R.W.H. Spatial delayed alternation of rats in a T-maze: Effects of neurotoxic lesions of the medial prefrontal cortex and of T-maze rotations. Behav Brain Res 84 (1997) 73-79
58. Sandeep T.C., Yau J.L.W., MacLullich A.M.J., Noble J., and Deary I.J. 11 beta-Hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics. Proc Natl Acad Sci U S A 101 (2004) 6734-6739
59. 2+ channels in nerve cell bodies of corpus striatum. J Neurochem 47 (1986) 1552-1557
60. Sapolsky R.M. Glucocorticoids and hippocampal atrophy in neuropsychiatric disorders. Arch Gen Psychiatry 57 (2000) 925-935
61. Sapolsky R.M. Stress, glucocorticoids and damage to the nervous system: the current state of confusion. Stress 1 (1996) 1-19
62. Schandler S.L., Clegg A.D., Thomas C.S., and Cohen M.J. Visuospatial information processing in intoxicated, recently detoxified, and long-term abstinent alcoholics. J Subst Abuse 8 (1996) 321-333
63. Seckl J.R., and Walker B.R. Minireview: 11β-hydroxysteroid dehydrogenase type-1: a tissue specific amplifier of glucocorticoid action. Endocrinology 142 (2001) 1371-1376
64. Smith J.W., and Little H.J. Differential effects of a dihydropyridine calcium channel antagonist the components of tolerance to the ataxic actions of ethanol. Brain Res 863 (2000) 9-19
65. Smith J.W., Watson W.P., Stephens D.N., and Little H.J. The calcium channel antagonist, nimodipine, decreases operant self-administration of low concentrations of ethanol. Behav Pharmacol 10 (1999) 793-802
66. Sullivan E.V., Rosenbloom M.J., and Pfefferbaum A. Pattern of motor and cognitive deficits in detoxified alcoholic men. Alcohol Clin Exp Res 24 5 (2000) 611-621
67. Sullivan E.V., Fama R., Rosenbloom M.J., and Pfefferbaum A. A profile of neuropsychological deficits in alcoholic women. Neuropsychology 16 (2002) 74-83
68. 3H]-PY200-110 with calcium channel binding sites in rat brain. J Neural Transm 60 (1984) 149-167
69. Thompson M.A., Ginty D.G., Bonni A., and Greenburg M.E. L-type voltage-sensitive calcium channel activation regulates c-fos transcription at multiple levels. J Biol Chem 270 (1995) 4224-4235
70. 2+ channels. J Biol Chem 282 (2007) 8464-8473
71. Tremwel M.F., and Hunter B.E. Effects of chronic ethanol ingestion on long-term potentiation remain even after a prolonged recovery from ethanol exposure. Synapse 17 (1994) 141-148
72. Uekermann J., Daum I., Schlebusch P., Wiebel B., and Trenckmann U. Depression and cognitive functioning in alcoholism. Addiction 98 (2003) 1521-1529
73. Veatch L.M., and Gonzalez L.P. Nifedipine alleviates alterations in hippocampal kindling after repeated ethanol withdrawal. Alcohol Clin Exp Res 24 (2000) 484-491
74. Watson W.P., and Little H.J. Selectivity of the effects of dihydropyridine calcium channel antagonists against the alcohol withdrawal syndrome. Brain Res 930 (2002) 111-122
75. Weber C.C., Eckert G.P., and Muller W.E. Effect of antidepressants on the brain/plasma distribution of corticosterone. Neuropsychopharmacology 31 (2006) 2443-2448
76. 2+ channels at the base of major dendrites in hippocampal pyramidal neurones. Nature 347 (1990) 281
77. Whittington M.A., and Little H.J. A calcium channel antagonist stereoselectively decreases ethanol withdrawal hyperexcitability, but not that due to bicuculline, in hippocampal slices. Br J Pharmacol 103 (1991) 1313-1320
78. Whittington M.A., Lambert J.D.C., and Little H.J. Increased NMDA-receptor and calcium channel activity during ethanol withdrawal hyperexcitability. Alcohol Alcohol 30 (1995) 105-114
79. Whittington M.A., Little H.J., and Lambert J.D.C. Changes in intrinsic inhibition in isolated hippocampal slices during ethanol withdrawal: lack of correlation with withdrawal hyperexcitability. Br J Pharmacol 107 (1992) 521-527
80. Winters B.D., and Bussey T.J. Removal of cholinergic input to perirhinal cortex disrupts object recognition but not spatial working memory in the rat. Eur J Neurosci 21 (2005) 2263-2270
81. Yau L.J.W., Noble J., Kenyon C.J., Hibberd C., and Kotelevtsev Y. Lack of tissue glucocorticoid reactivation in 11-β-hydroxysteroid dehydrogenase type 1 knockout mice ameliorates age-related learning impairments. Proc Natl Acad Sci U S A 98 (2001) 4716-4721
82. Young A.H., Gallagher P., Watson S., Del-Estal D., Owen B.M., and Ferrier I.N. Improvements in neurocognitive function and mood following adjunctive treatment with mifepristone (RU-486) in bipolar disorder. Neuropsychopharmacology 29 (2004) 1538-1545
83. Zhang X.L., Begleiter H., and Porjesz B. Electrophysiological evidence of memory impairment in alcoholic patients. Biol Psychiatry 42 (1997) 1157-1171
84. 2+ channel blockers inhibit the development but not the expression of sensitization to morphine in mice. Eur J Pharmacol 467 (2003) 145-150
85. Zinn S., Stein R., and Swartzwelder H.S. Executive functioning early in abstinence from alcohol. Alcohol Clin Exp Res 28 (2004) 1338-1346