L-type fatty acid binding protein transgenic mouse as a novel tool to explore cytotoxicity to renal proximal tubules

Drug Metabolism and Pharmacokinetics

Volumn 23, Issue 4, 2008, Pages 271-278

  Nakamura, Kazuo ^a   Ito, Kimihiro ^b   Kato, Yukio ^b   Sugaya, Takeshi ^a   Kubo, Yoshiyuki ^b   Tsuji, Akira ^b  

^a Strategic and Regulatory Affairs Consulting Department   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

Drug screening; Nephrotoxicity; Proximal tubules; Transporters

Indexed keywords

CEFALORIDINE; CIMETIDINE; CISPLATIN; CREATININE; FATTY ACID BINDING PROTEIN; FABP1 PROTEIN, MOUSE; ORGANIC CATION TRANSPORTER; SLC22A2 PROTEIN, HUMAN; SLC22A2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG UPTAKE; KIDNEY PROXIMAL TUBULE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PROTEIN URINE LEVEL; SINGLE DRUG DOSE; TRANSGENIC MOUSE; UREA NITROGEN BLOOD LEVEL; ANIMAL; BLOOD; C57BL MOUSE; DRUG EFFECT; DRUG SCREENING; METHODOLOGY; PHYSIOLOGY;

ANIMALS; BLOOD UREA NITROGEN; CEPHALORIDINE; CIMETIDINE; CISPLATIN; CREATININE; DRUG EVALUATION, PRECLINICAL; FATTY ACID-BINDING PROTEINS; KIDNEY TUBULES, PROXIMAL; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; ORGANIC CATION TRANSPORT PROTEINS;

EID: 56149122770     PISSN: 13474367     EISSN: 18800920     Source Type: Journal    
DOI: 10.2133/dmpk.23.271     Document Type: Article

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