Manganese-enhanced MRI of the DBA/2J mouse model of hereditary glaucoma

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 11, 2008, Pages 5083-5088

  Calkins, David J ^a   Horner, Philip J ^b   Roberts, Robin ^c   Gradianu, Marius ^c   Berkowitz, Bruce A ^c,d  

^a VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ION; MANGANESE; DIAGNOSTIC AGENT; TRACE ELEMENT;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CILIARY BODY; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; CORNEA; DBA 2 MOUSE; EYE; GLAUCOMA; HEREDITY; LIGHT ADAPTATION; MOUSE; MOUSE STRAIN; NERVE FIBER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTIC NERVE; PERIMETER; PRIORITY JOURNAL; RETINA; ANIMAL; C57BL MOUSE; DBA MOUSE; DISEASE MODEL; FOLLOW UP; GENETICS; HOSPITALIZATION; METABOLISM; METHODOLOGY; OPEN ANGLE GLAUCOMA; OPTIC DISK; PATHOLOGY; REPRODUCIBILITY;

ANIMALS; AXONS; CILIARY BODY; DISEASE MODELS, ANIMAL; FOLLOW-UP STUDIES; GLAUCOMA, OPEN-ANGLE; MAGNETIC RESONANCE IMAGING; MANGANESE; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; OPTIC DISK; REPRODUCIBILITY OF RESULTS; RETINA; SEVERITY OF ILLNESS INDEX; TRACE ELEMENTS;

EID: 56149111959     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2205     Document Type: Article

References (43)

1. Jay JL, Murdoch JR. The rate of visual field loss in untreated primary open angle glaucoma. Br J Ophthalmol. 1993;77(3):176-178. (Pubitemid 23092507)
2. Quigley HA. Current and future approaches to glaucoma screening. J Glaucoma. 1998;7(3):210-220. (Pubitemid 28301630)
3. Jonas JB, Budde WM. Diagnosis and pathogenesis of glaucomatous optic neuropathy: morphological aspects1. Prog Retin Eye Res. 2000;19(1):1-40.
4. Nickells RW. Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death. Surv Ophthalmol. 1999;43(suppl 1):S151-S161.
5. Osborne NN, Wood JPM, Chidlow G, Casson R, DeSantis L, Schmidt K-G. Effectiveness of levobetaxolol and timolol at blunting retinal ischaemia is related to their calcium and sodium blocking activities: relevance to glaucoma. Brain Res Bull. 2004;15;62(6):525-528. (Pubitemid 38253038)
6. Hirooka K, Kelly MEM, Baldridge WH, Barnes S. Suppressive actions of betaxolol on ionic currents in retinal ganglion cells may explain its neuroprotective effects. Exp Eye Res. 2000;70(5):611-621. (Pubitemid 30671669)
7. Kelly MEM, Barnes S. Physiology and pathophysiology of nitric oxide in the retina. Neuroscientist. 1997;3(6):357-360. (Pubitemid 127532815)
8. Inman DM, Sappington RM, Horner PJ, Calkins DJ. Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma. Invest Ophthalmol Vis Sci. 2006;47(3):986-996.
9. Chan KC, Fu QL, So KF, Wu EX. Evaluation of the visual system in a rat model of chronic glaucoma using manganese-enhanced magnetic resonance imaging. Conf Proc IEEE Eng Med Biol Soc. 2007;1:67-70.
10. Stys PK, Waxman SG, Ransom BR. Ionic mechanisms of anoxic injury in mammalian CNS white matter: role of Na+ channels and Na(+)-Ca2+ exchanger. J Neurosci. 1992;12(2):430-439.
11. Ishii Y, Kwong JM, Caprioli J. Retinal ganglion cell protection with geranylgeranylacetone, a heat shock protein inducer, in a rat glaucoma model. Invest Ophthalmol Vis Sci. 2003;44(5):1982-1992. (Pubitemid 36520289)
12. Zhang J, Wu SM, Gross RL. Effects of [beta]-adrenergic blockers on glutamate-induced calcium signals in adult mouse retinal ganglion cells. Brain Res. 2003;959(1):111-119. (Pubitemid 35435411)
13. Berkowitz BA, Roberts R, Luan H, et al. Manganese-enhanced MRI studies of alterations of intraretinal ion demand in models of ocular injury. Invest Ophthalmol Vis Sci. 2007;48(8):3796-3804. (Pubitemid 351261120)
14. Berkowitz BA, Roberts R, Stemmler A, Luan H, Gradianu M. Impaired apparent ion demand in experimental diabetic retinopathy: correction by lipoic acid. Invest Ophthalmol Vis Sci. 2007;48(10):4753-4758. (Pubitemid 351260995)
15. Berkowitz BA, Roberts R, Penn JS, Gradianu M. High-resolution manganese-enhanced MRI of experimental retinopathy of prematurity. Invest Ophthalmol Vis Sci. 2007;48(10):4733-4740. (Pubitemid 351260992)
16. Braun RD, Gradianu M, Vistisen KS, Roberts RL, Berkowitz BA. Manganese-enhanced MRI of human choroidal melanoma xenografts. Invest Ophthalmol Vis Sci. 2007;48(3):963-967. (Pubitemid 351261383)
17. Wendland MF. Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to imaging of the heart. NMR Biomed. 2004;17(8):581-594. (Pubitemid 40124783)
18. Lin YJ, Koretsky AP. Manganese ion enhances T1-weighted MRI during brain activation: an approach to direct imaging of brain function. Magn Reson Med. 1997;38(3):378-388.
19. Berkowitz BA, Roberts R, Luan H, et al. Manganese-enhanced MRI studies of alterations of intraretinal ion demand in models of ocular injury. Invest Ophthalmol Vis Sci. 2007;48(8):3796-3804. (Pubitemid 351261120)
20. Berkowitz BA, Roberts R, Goebel DJ, Luan H. Noninvasive and simultaneous imaging of layer-specific retinal functional adaptation by manganese-enhanced MRI. Invest Ophthalmol Vis Sci. 2006;47(6):2668-2674. (Pubitemid 351639856)
21. Lu H, Xi ZX, Gitajn L, Rea W, Yang Y, Stein EA. Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI). Proc Natl Acad Sci U S A. 2007;104(7):2489-2494. (Pubitemid 46391423)
22. Schuettauf F, Quinto K, Naskar R, Zurakowski D. Effects of antiglaucoma medications on ganglion cell survival: the DBA/2J mouse model. Vision Res. 2002;42(20):2333-2337. (Pubitemid 35279167)
23. Zhou X, Li F, Kong L, Tomita H, Li C, Cao W. Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma. J Biol Chem. 2005;280(35):31240-31248. (Pubitemid 41291861)
24. Jakobs TC, Libby RT, Ben Y, John SW, Masland RH. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. J Cell Biol. 2005;171(2):313-325. (Pubitemid 41540023)
25. Inman DM, Sappington RM, Horner PJ, Calkins DJ. Quantitative correlation of optic nerve pathology with ocular pressure and corneal thickness in the DBA/2 mouse model of glaucoma. Invest Ophthalmol Vis Sci. 2006;47(3):986-996.
26. John SW, Smith RS, Savinova OV, et al. Essential iris atrophy, pigment dispersion, and glaucoma in DBA/2J mice. Invest Ophthalmol Vis Sci. 1998;39(6):951-962.
27. Anderson MG, Smith RS, Savinova OV, et al. Genetic modification of glaucoma associated phenotypes between AKXD-28/Ty and DBA/2J mice. BMC Genet. 2001;2:1.
28. Howell GR, Libby RT, Jakobs TC, et al. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. J Cell Biol. 2007;179(7):1523-1537.
29. Saleh M, Nagaraju M, Porciatti V. Longitudinal evaluation of retinal ganglion cell function and IOP in the DBA/2J mouse model of glaucoma. Invest Ophthalmol Vis Sci. 2007;48(10):4564-4572. (Pubitemid 351260973)
30. Sawada T, Nakamura J, Nishida Y, Kani K, Morikawa S, Inubushi T. Magnetic resonance imaging studies of the volume of the rabbit eye with intravenous mannitol. Curr Eye Res. 2002;25(3):173-177. (Pubitemid 36842946)
31. Luan H, Roberts R, Sniegowski M, Goebel DJ, Berkowitz BA. Retinal thickness and subnormal retinal oxygenation response in experimental diabetic retinopathy. Invest Ophthalmol Vis Sci. 2006;47(1):320-328. (Pubitemid 46780831)
32. Liang Z. Longitudinal data analysis using generalized linear models. Biometrika. 1986;73:13-22.
33. Buckingham BP, Inman DM, Lambert W, et al. Progressive ganglion cell degeneration precedes neuronal loss in a mouse model of glaucoma. J Neurosci. 2008;28(11):2735-2744.
34. Gordon MO, Beiser JA, Brandt JD, et al. The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma. Arch Ophthalmol. 2002;120(6):714-720.
35. Tuck MW, Crick RP. Glaucoma detection rate: a useful concept, to be distinguished from accuracy of referral (positive predictive value). Ophthalmic Physiol Opt. 1998;18(6):545-546.
36. Yu X, Wadghiri YZ, Sanes DH, Turnbull DH. In vivo auditory brain mapping in mice with Mn-enhanced MRI. Nat Neurosci. 2005;8(7):961-968.
37. Silva AC, Lee JH, Aoki I, Koretsky AP. Manganese-enhanced magnetic resonance imaging (MEMRI): methodological and practical considerations. NMR Biomed. 2004;17(8):532-543. (Pubitemid 40124779)
38. Lindsey JD, Scadeng M, Dubowitz DJ, Crowston JG, Weinreb RN. Magnetic resonance imaging of the visual system in vivo: transsynaptic illumination of V1 and V2 visual cortex. Neuroimage. 200715;34(4):1619-1626.
39. Bearer EL, Falzone TL, Zhang X, Biris O, Rasin A, Jacobs RE. Role of neuronal activity and kinesin on tract tracing by manganese-enhanced MRI (MEMRI). Neuroimage. 2007;37(suppl 1):S37-S46. (Pubitemid 47239432)
40. Li Q, Timmers AM, Hunter K, Gonzalez-Pola C, et al. Noninvasive imaging by optical coherence tomography to monitor retinal degeneration in the mouse. Invest Ophthalmol Vis Sci. 2001;42(12):2981-2989. (Pubitemid 33035300)
41. Remtulla S, Hallett PE. A schematic eye for the mouse, and comparisons with the rat. Vision Res. 1985;25(1):21-31. (Pubitemid 15165475)
42. Kim KH, Puoris'haag M, Maguluri GN, et al. Monitoring mouse retinal degeneration with high-resolution spectral-domain optical coherence tomography. J Vision. 2008;8(1):1-11.
43. Feng L, Sun Z, Han H, Zhou Y, Zhang M. No cell loss in three retinal nuclear layers of the Long-Evans rat. Vis Neurosci. 2007;24(6):799-803.