Effect of low dose of vinclozolin on reproductive tract development and sperm parameters in CD1 outbred mice

Reproductive Toxicology

Volumn 26, Issue 3-4, 2008, Pages 231-238

  Elzeinova, Fatima ^a   Novakova, Vendula ^a   Buckiova, Daniela ^b   Kubatova, Alena ^a   Peknicova, Jana ^a  

^a INSTITUTE OF BIOTECHNOLOGY   (Czech Republic)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

Author keywords

Apoptosis; Intra acrosomal proteins; Reproductive organs; Sperm parameters; Ubiquitination; Vinclozolin

Indexed keywords

VINCLOZOLIN;

ACROSOME; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENITAL SYSTEM; MALE; MOUSE; NONHUMAN; ORGANOGENESIS; PREGNANCY; PROSTATE; PUBERTY; SPERM; SPERMATOZOON; SPERMATOZOON ABNORMALITY; SPERMATOZOON COUNT; TESTIS;

ANDROGEN ANTAGONISTS; ANIMALS; BODY WEIGHT; FEMALE; FETUS; FUNGICIDES, INDUSTRIAL; GENITALIA, MALE; MALE; MICE; MICE, INBRED ICR; ORGAN SIZE; OXAZOLES; PREGNANCY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPERMATOGENESIS; TESTIS; UBIQUITIN;

MUS;

EID: 56149104710     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.reprotox.2008.09.007     Document Type: Article

References (38)

1. Møller H. Trends in incidence of testicular cancer and prostate cancer in Denmark. Hum Reprod 16 (2001) 1007-1011
2. Ganmaa D., Li X.M., Qin L.Q., Wang P.Y., Takeda M., and Sato A. The experience of Japan as a clue to the etiology of testicular and prostatic cancers. Med Hypotheses 60 (2003) 724-730
3. Carlsen E., Giwercman A., Keiding N., and Skakkebaek N.E. Evidence for decreasing quality of semen during past 50 years. Br Med J 305 (1992) 609-613
4. Andersen A.G., Jensen T.K., Carlsen E., et al. High frequency of sub-optimal semen quality in an unselected population of young men. Hum Reprod 15 (2000) 366-372
5. Ansell P.E., Bennet V., Bull D., et al. Cryptochidism: a prospective study of 7500 consecutive male births, 1984-8. Arch Dis Childhood 67 (1992) 892-899
6. Jensen T.K., Toppari J., Keiding N., and Skakkebaek N.E. Do environmental estrogens contribute to the decline in male reproductive health?. Clin Chem 41 (1995) 1896-1901
7. Skakkebæk N.E., Rajpert-DeMeyts E., and Main K.M. Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects. Hum Reprod 16 (2001) 972-978
8. Fisher J.S. Environmental anti-androgens and male reproductive health: focus on phthalates and testicular dysgenesis syndrome. Reproduction 127 (2004) 305-315
9. Gray L.E., Ostby J., Furr J., et al. Effects of environmental antiandrogens on reproductive development in experimental animals. Hum Reprod Update 7 (2001) 248-264
10. Hellwig J., van Ravenzwaay B., Mayer M., and Gembardt C. Pre- and postnatal oral toxicity of vinclozolin in Wistar and Long-Evans rats. Regul Toxicol Pharmacol 32 (2000) 42-50
11. Anway M.D., and Skinner M.K. Transgenerational effects of the endocrine disruptor vinclozolin on the prostate transcriptome and adult onset disease. Prostate 68 (2008) 517-529
12. Chang H.S., Anway M.D., Rekow S.S., and Skinner M.K. Transgenerational epigenetic imprinting of the male germline by endocrine disruptor exposure during gonadal sex determination. Endocrinology 147 (2006) 5524-5541
13. Shimamura M., Kodaira K., Kenichi H., Ishimoto Y., Tamura H., and Iguchi T. Comparison of antiadrogenic activities of vinclozolin and d,l-camphorquinone in adrogen receptor gene transcription assay in vitro and mouse in utero exposure assay in vivo. Toxicology 174 (2002) 97-107
14. Yu W.J., Lee B.J., Nam S.Y., et al. Reproductive disorders in pubertal and adult phase of the male rats exposed to vinclozolin during puberty. J Vet Med Sci 66 (2004) 847-853
15. Chomczynski P., and Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162 (1987) 156-159
16. Peknicova J., Kyselova V., Buckiova D., and Boubelik M. Effect of an endocrine disruptor on mammalian fertility. Application of monoclonal antibodies against sperm proteins as markers for testing sperm damage. Am J Reprod Immunol 47 (2002) 311-318
17. Peknicova J., Chladek D., and Hozak P. Monoclonal antibodies against spem antigens as markers for detection of physiology and pathology of human spermatozoa and estimation of spermatogenesis. Am J Immunol Reprod 53 (2005) 1-8
18. Capkova J., Geussova G., and Peknicova J. Monoclonal antibody to human sperm acrosomal protein. Folia Biol 46 (2000) 55-57
19. Moormen W.J., Cheever K.L., Skaggs S.R., Clark J.C., Turner T.W., Marlow K.L., et al. Male adolescent exposure to endocrine-disrupting pesticides: vinclozolin exposure in peripubertal rabbits. Andrologia 32 (2000) 285-293
20. Gray Jr. L.E., Ostby J., Monosson E., and Kelce W.R. Environmental antiandrogens: low doses of the fungicide vinclozolin alter sexual differentiation of the male rat. Toxicol Ind Health 15 (1999) 48-64
21. Kubota K., Ohsako S., Kurosawa S., et al. Effects of vinclozolin administration on sperm and testosterone biosynthetic pathway in adult male rat. J Reprod Dev 49 (2003) 403-412
22. Vojtiskova M., Polackova M., Viklicky V., and Khoda M.E. Reversible inhibitory effect of the non-steroidal antiandrogen flutamide (SCH 13521) on spermatogenesis in mice. Endokrinologie 71 (1987) 135-142
23. Sutovsky P., Neuber E., and Shatten G. Ubiquitin-dependent sperm quality control mechanism recognizes spermatozoa with DNA defects as revealed by dual ubiquitin-TUNEL assay. Mol Reprod Dev 61 (2002) 406-413
24. Pena F.J., Johannisson A., Wallgren M., and Rodriguez-Martinez H. Assessment of fresh and frozen-thawed boar semen using an annexin-V assay: a new method of evaluating sperm membrane integrity. Theriogenology 60 (2003) 677-689
25. Kyselova V., Peknicova J., Buckiova D., and Boubelik M. Effects of p-nonylphenol and resveratrol on body and organ weight and in vivo fertility of outbred CD-1 mice. Reprod Biol Endocrinol 1 (2003) 30. www.rbej.com
26. Kyselova V., Peknicova J., Boubelik M., and Buckiova D. Body and organ weight, sperm acrosomal status and reproduction after genistein and diethylstilbestrol treatment of CD1 mice in a multigenerational study. Theriogenology 61 (2004) 1307-1325
27. Tang P.Z., Tsai-Morris C.H., and Dufau M.L. A novel gonadotropin-regulated testicular RNA helicase. A new member of the dead-box family. J Biol Chem 274 (1999) 37932-37940
28. Tsai-Morris C.H., Sheng Y., Lee E., Lei K.J., and Dufau M.L. Gonadotropin-regulated testicular RNA helicase (GRTH/Ddx25) is essential for spermatid development and completion of spermatogenesis. Proc Natl Acad Sci. USA 101 (2004) 6373-6378
29. Tai P.K., and Faber L.E. Isolation of dissimilar components of the 8.5S nonactivated uterine progestin receptor. Can J Biochem Cell Biol 63 (1985) 41-49
30. Radanyi C., Chambraud B., and Baulieu E.E. The ability of the immunophilin FKBP59-HBI to interact with the 90-kDa heat shock protein is encoded by its tetratricopeptide repeat domain. Proc Natl Acad Sci. USA 91 (1994) 11197-111201
31. Zhu W., Zhang J.S., and Young C.Y. Silymarin inhibits function of the androgen receptor by reducing nuclear localization of the receptor in the human prostate cancer cell line LNCaP. Carcinogenesis 22 (2001) 1399-1403
32. Kaneko Y., Kimura T., Nishiyama H., Noda Y., and Fujita J. Developmentally regulated expression of APG-1, a member of heat shock protein 110 family in murine male germ cells. Biochem Biophys Res Commun 233 (1997) 113-116
33. Nonoguchi K., Tokuchi H., Okuno H., et al. Expression of Apg-1, a member of the Hsp110 family, in the human testis and sperm. Int J Urol 8 (2001) 308-314
34. Sutovsky P., Moreno R., Ramalho-Santos J., Dominko T., Thompson W.E., and Schatten G. A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis. J Cell Sci 114 (2001) 1665-1675
35. Sutovsky P., Turner R.M., Hameed S., and Sutovsky M. Differential ubiquitination of stallion sperm proteins: possible implications for infertility and reproductive seasonality. Biol Reprod 68 (2003) 688-698
36. Lu N.X., Xia Y.K., Gu A.H., Liang J., Wang S.L., and Wang X.R. Lack of association between polymorphisms in p53 gene and spermatogenetic failure in a Chinese population. Andrologia 39 (2007) 223-228
37. Woolveridge I., Bryden A.A., Taylor M.F., George N.J., Wu F.C., and Morris I.D. Apoptosis and expression of apoptotic regulators in the human testis following short- and long-term anti-androgen treatment. Mol Hum Reprod 4 (1998) 701-707
38. Kaushal N., and Bansal M.P. Inhibition of CDC2/Cyclin B1 in response to selenium-induced oxidative stress during spermatogenesis: potential role of Cdc25c and p21. Mol Cell Biochem 298 (2007) 139-150