Glucocorticoids inhibit nontypeable Haemophilus influenzae-induced MUC5AC mucin expression via MAPK phosphatase-1-dependent inhibition of p38 MAPK

Biochemical and Biophysical Research Communications

Volumn 377, Issue 3, 2008, Pages 763-768

  Komatsu, Kensei ^a   Jono, Hirofumi ^a   Lim, Jae Hyang ^a   Imasato, Akira ^a   Xu, Haidong ^a   Kai, Hirofumi ^b   Yan, Chen ^a   Li, Jian Dong ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Glucocorticoids; MKP 1; MUC5AC mucin; Nontypeable Haemophilus influenzae; p38 MAPK

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MUCIN 5AC;

ANIMAL TISSUE; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; GENE; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; HUMAN; HUMAN CELL; MALE; MOUSE; MUC5AC GENE; NONHUMAN; OTITIS MEDIA; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; UPREGULATION;

CELL LINE, TUMOR; DEXAMETHASONE; DUAL SPECIFICITY PHOSPHATASE 1; GLUCOCORTICOIDS; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HUMANS; MUCIN 5AC; OTITIS MEDIA; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

BACTERIA (MICROORGANISMS); HAEMOPHILUS INFLUENZAE;

EID: 56049100893     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.091     Document Type: Article

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