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Volumn 18, Issue 5, 2008, Pages 397-403

Message in a nucleus: signaling to the transcriptional machinery

Author keywords

[No Author keywords available]

Indexed keywords

REGULATOR PROTEIN; RNA POLYMERASE II; TRANSCRIPTION FACTOR;

EID: 56049084903     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gde.2008.07.007     Document Type: Review
Times cited : (17)

References (71)
  • 1
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • Li B., Carey M., and Workman J.L. The role of chromatin during transcription. Cell 128 (2007) 707-719
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 2
    • 0034912714 scopus 로고    scopus 로고
    • Transcriptional coactivator complexes
    • Naar A.M., Lemon B.D., and Tjian R. Transcriptional coactivator complexes. Annu Rev Biochem 70 (2001) 475-501
    • (2001) Annu Rev Biochem , vol.70 , pp. 475-501
    • Naar, A.M.1    Lemon, B.D.2    Tjian, R.3
  • 3
    • 33747881750 scopus 로고    scopus 로고
    • The general transcription machinery and general cofactors
    • Thomas M.C., and Chiang C.M. The general transcription machinery and general cofactors. Crit Rev Biochem Mol Biol 41 (2006) 105-178
    • (2006) Crit Rev Biochem Mol Biol , vol.41 , pp. 105-178
    • Thomas, M.C.1    Chiang, C.M.2
  • 4
    • 36248971192 scopus 로고    scopus 로고
    • On a roll for new TRF targets
    • Reina J.H., and Hernandez N. On a roll for new TRF targets. Genes Dev 21 (2007) 2855-2860
    • (2007) Genes Dev , vol.21 , pp. 2855-2860
    • Reina, J.H.1    Hernandez, N.2
  • 5
    • 18844394569 scopus 로고    scopus 로고
    • Dynamic regulation of pol II transcription by the mammalian Mediator complex
    • Malik S., and Roeder R.G. Dynamic regulation of pol II transcription by the mammalian Mediator complex. Trends Biochem Sci 30 (2005) 256-263
    • (2005) Trends Biochem Sci , vol.30 , pp. 256-263
    • Malik, S.1    Roeder, R.G.2
  • 6
    • 18844461272 scopus 로고    scopus 로고
    • Interactions between subunits of Drosophila Mediator and activator proteins
    • Kim Y.J., and Lis J.T. Interactions between subunits of Drosophila Mediator and activator proteins. Trends Biochem Sci 30 (2005) 245-249
    • (2005) Trends Biochem Sci , vol.30 , pp. 245-249
    • Kim, Y.J.1    Lis, J.T.2
  • 7
    • 33745790132 scopus 로고    scopus 로고
    • Chromatin remodelling: the industrial revolution of DNA around histones
    • Saha A., Wittmeyer J., and Cairns B.R. Chromatin remodelling: the industrial revolution of DNA around histones. Nat Rev Mol Cell Biol 7 (2006) 437-447
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 437-447
    • Saha, A.1    Wittmeyer, J.2    Cairns, B.R.3
  • 8
    • 15244346915 scopus 로고    scopus 로고
    • Swapping function of two chromatin remodeling complexes
    • Fan H.Y., Trotter K.W., Archer T.K., and Kingston R.E. Swapping function of two chromatin remodeling complexes. Mol Cell 17 (2005) 805-815
    • (2005) Mol Cell , vol.17 , pp. 805-815
    • Fan, H.Y.1    Trotter, K.W.2    Archer, T.K.3    Kingston, R.E.4
  • 9
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 128 (2007) 693-705
    • (2007) Cell , vol.128 , pp. 693-705
    • Kouzarides, T.1
  • 10
    • 33748419671 scopus 로고    scopus 로고
    • Polycomb response elements and targeting of Polycomb group proteins in Drosophila
    • Muller J., and Kassis J.A. Polycomb response elements and targeting of Polycomb group proteins in Drosophila. Curr Opin Genet Dev 16 (2006) 476-484
    • (2006) Curr Opin Genet Dev , vol.16 , pp. 476-484
    • Muller, J.1    Kassis, J.A.2
  • 11
    • 4143098311 scopus 로고    scopus 로고
    • CBP and p300: HATs for different occasions
    • Kalkhoven E. CBP and p300: HATs for different occasions. Biochem Pharmacol 68 (2004) 1145-1155
    • (2004) Biochem Pharmacol , vol.68 , pp. 1145-1155
    • Kalkhoven, E.1
  • 12
    • 44349108499 scopus 로고    scopus 로고
    • The emerging field of dynamic lysine methylation of non-histone proteins
    • Huang J., and Berger S.L. The emerging field of dynamic lysine methylation of non-histone proteins. Curr Opin Genet Dev 18 (2008) 152-158
    • (2008) Curr Opin Genet Dev , vol.18 , pp. 152-158
    • Huang, J.1    Berger, S.L.2
  • 15
    • 27644467360 scopus 로고    scopus 로고
    • Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation
    • This paper shows that TAFs specific to the Drosophila testis promote activation of genes important for spermatid differentiation by relocalizing PRC1 components to the nucleolus and by promoting lysine methylation of H3K4.
    • Chen X., Hiller M., Sancak Y., and Fuller M.T. Tissue-specific TAFs counteract Polycomb to turn on terminal differentiation. Science 310 (2005) 869-872. This paper shows that TAFs specific to the Drosophila testis promote activation of genes important for spermatid differentiation by relocalizing PRC1 components to the nucleolus and by promoting lysine methylation of H3K4.
    • (2005) Science , vol.310 , pp. 869-872
    • Chen, X.1    Hiller, M.2    Sancak, Y.3    Fuller, M.T.4
  • 16
    • 0038325615 scopus 로고    scopus 로고
    • The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation
    • Pointud J.C., Mengus G., Brancorsini S., Monaco L., Parvinen M., Sassone-Corsi P., and Davidson I. The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation. J Cell Sci 116 (2003) 1847-1858
    • (2003) J Cell Sci , vol.116 , pp. 1847-1858
    • Pointud, J.C.1    Mengus, G.2    Brancorsini, S.3    Monaco, L.4    Parvinen, M.5    Sassone-Corsi, P.6    Davidson, I.7
  • 17
    • 0034927769 scopus 로고    scopus 로고
    • Cell- and stage-specific high-level expression of TBP-related factor 2 (TRF2) during mouse spermatogenesis
    • Zhang D., Penttila T.L., Morris P.L., and Roeder R.G. Cell- and stage-specific high-level expression of TBP-related factor 2 (TRF2) during mouse spermatogenesis. Mech Dev 106 (2001) 203-205
    • (2001) Mech Dev , vol.106 , pp. 203-205
    • Zhang, D.1    Penttila, T.L.2    Morris, P.L.3    Roeder, R.G.4
  • 18
    • 0036336406 scopus 로고    scopus 로고
    • Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids
    • Martianov I., Brancorsini S., Gansmuller A., Parvinen M., Davidson I., and Sassone-Corsi P. Distinct functions of TBP and TLF/TRF2 during spermatogenesis: requirement of TLF for heterochromatic chromocenter formation in haploid round spermatids. Development 129 (2002) 945-955
    • (2002) Development , vol.129 , pp. 945-955
    • Martianov, I.1    Brancorsini, S.2    Gansmuller, A.3    Parvinen, M.4    Davidson, I.5    Sassone-Corsi, P.6
  • 19
    • 0035860472 scopus 로고    scopus 로고
    • Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development
    • Freiman R.N., Albright S.R., Zheng S., Sha W.C., Hammer R.E., and Tjian R. Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development. Science 293 (2001) 2084-2087
    • (2001) Science , vol.293 , pp. 2084-2087
    • Freiman, R.N.1    Albright, S.R.2    Zheng, S.3    Sha, W.C.4    Hammer, R.E.5    Tjian, R.6
  • 21
    • 33644533505 scopus 로고    scopus 로고
    • Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks
    • Geles K.G., Freiman R.N., Liu W.L., Zheng S., Voronina E., and Tjian R. Cell-type-selective induction of c-jun by TAF4b directs ovarian-specific transcription networks. Proc Natl Acad Sci U S A 103 (2006) 2594-2599
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2594-2599
    • Geles, K.G.1    Freiman, R.N.2    Liu, W.L.3    Zheng, S.4    Voronina, E.5    Tjian, R.6
  • 22
    • 38349074012 scopus 로고    scopus 로고
    • Structural changes in TAF4b-TFIID correlate with promoter selectivity
    • This paper shows that incorporation of TAF4b into the TFIID complex alters both its structure and its core promoter specificity, increasing activator binding to the target c-jun promoter.
    • Liu W.L., Coleman R.A., Grob P., King D.S., Florens L., Washburn M.P., Geles K.G., Yang J.L., Ramey V., Nogales E., et al. Structural changes in TAF4b-TFIID correlate with promoter selectivity. Mol Cell 29 (2008) 81-91. This paper shows that incorporation of TAF4b into the TFIID complex alters both its structure and its core promoter specificity, increasing activator binding to the target c-jun promoter.
    • (2008) Mol Cell , vol.29 , pp. 81-91
    • Liu, W.L.1    Coleman, R.A.2    Grob, P.3    King, D.S.4    Florens, L.5    Washburn, M.P.6    Geles, K.G.7    Yang, J.L.8    Ramey, V.9    Nogales, E.10
  • 23
    • 34548427818 scopus 로고    scopus 로고
    • Switching of the core transcription machinery during myogenesis
    • The authors demonstrate a dramatic transformation of the basal transcriptional machinery when myoblasts differentiate into myotubes. TFIID disappears and is replaced by TRF3 and TAF3, which are required for the transcription of muscle-specific genes such as myogenin.
    • Deato M.D., and Tjian R. Switching of the core transcription machinery during myogenesis. Genes Dev 21 (2007) 2137-2149. The authors demonstrate a dramatic transformation of the basal transcriptional machinery when myoblasts differentiate into myotubes. TFIID disappears and is replaced by TRF3 and TAF3, which are required for the transcription of muscle-specific genes such as myogenin.
    • (2007) Genes Dev , vol.21 , pp. 2137-2149
    • Deato, M.D.1    Tjian, R.2
  • 24
    • 37249014601 scopus 로고    scopus 로고
    • Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3
    • Hart D.O., Raha T., Lawson N.D., and Green M.R. Initiation of zebrafish haematopoiesis by the TATA-box-binding protein-related factor Trf3. Nature 450 (2007) 1082-1085
    • (2007) Nature , vol.450 , pp. 1082-1085
    • Hart, D.O.1    Raha, T.2    Lawson, N.D.3    Green, M.R.4
  • 25
    • 34447249019 scopus 로고    scopus 로고
    • An essential switch in subunit composition of a chromatin remodeling complex during neural development
    • The authors identify subunits of the SWI/SNF chromatin-remodeling complex that undergo isoform switching during neuronal differentiation in the mouse spinal cord. One progenitor-specific subunit isoform, BAF45a, is necessary and sufficient for continued cell proliferation.
    • Lessard J., Wu J.I., Ranish J.A., Wan M., Winslow M.M., Staahl B.T., Wu H., Aebersold R., Graef I.A., and Crabtree G.R. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron 55 (2007) 201-215. The authors identify subunits of the SWI/SNF chromatin-remodeling complex that undergo isoform switching during neuronal differentiation in the mouse spinal cord. One progenitor-specific subunit isoform, BAF45a, is necessary and sufficient for continued cell proliferation.
    • (2007) Neuron , vol.55 , pp. 201-215
    • Lessard, J.1    Wu, J.I.2    Ranish, J.A.3    Wan, M.4    Winslow, M.M.5    Staahl, B.T.6    Wu, H.7    Aebersold, R.8    Graef, I.A.9    Crabtree, G.R.10
  • 26
    • 34748887795 scopus 로고    scopus 로고
    • Regulation of dendritic development by neuron-specific chromatin remodeling complexes
    • Wu J.I., Lessard J., Olave I.A., Qiu Z., Ghosh A., Graef I.A., and Crabtree G.R. Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron 56 (2007) 94-108
    • (2007) Neuron , vol.56 , pp. 94-108
    • Wu, J.I.1    Lessard, J.2    Olave, I.A.3    Qiu, Z.4    Ghosh, A.5    Graef, I.A.6    Crabtree, G.R.7
  • 27
    • 14544308853 scopus 로고    scopus 로고
    • Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes
    • Mohrmann L., and Verrijzer C.P. Composition and functional specificity of SWI2/SNF2 class chromatin remodeling complexes. Biochim Biophys Acta 1681 (2005) 59-73
    • (2005) Biochim Biophys Acta , vol.1681 , pp. 59-73
    • Mohrmann, L.1    Verrijzer, C.P.2
  • 28
    • 44349105786 scopus 로고    scopus 로고
    • ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a
    • Gao X., Tate P., Hu P., Tjian R., Skarnes W.C., and Wang Z. ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A 105 (2008) 6656-6661
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6656-6661
    • Gao, X.1    Tate, P.2    Hu, P.3    Tjian, R.4    Skarnes, W.C.5    Wang, Z.6
  • 29
    • 47949107720 scopus 로고    scopus 로고
    • BAF250B-associated SWI/SNF chromatin-remodeling Complex is required to maintain undifferentiated mouse embryonic stem cells
    • Yan Z., Wang Z., Sharova L., Sharov A.A., Ling C., Piao Y., Aiba K., Matoba R., Wang W., and Ko M.S. BAF250B-associated SWI/SNF chromatin-remodeling Complex is required to maintain undifferentiated mouse embryonic stem cells. Stem Cells 26 (2008) 1155-1165
    • (2008) Stem Cells , vol.26 , pp. 1155-1165
    • Yan, Z.1    Wang, Z.2    Sharova, L.3    Sharov, A.A.4    Ling, C.5    Piao, Y.6    Aiba, K.7    Matoba, R.8    Wang, W.9    Ko, M.S.10
  • 31
    • 0034671765 scopus 로고    scopus 로고
    • Osa-containing Brahma chromatin remodeling complexes are required for the repression of Wingless target genes
    • This paper shows that Osa, a subunit specific to one form of the Brahma chromatin-remodeling complex, has a specific developmental function, repressing target genes regulated by the Wnt protein Wingless.
    • Collins R.T., and Treisman J.E. Osa-containing Brahma chromatin remodeling complexes are required for the repression of Wingless target genes. Genes Dev. 14 (2000) 3140-3152. This paper shows that Osa, a subunit specific to one form of the Brahma chromatin-remodeling complex, has a specific developmental function, repressing target genes regulated by the Wnt protein Wingless.
    • (2000) Genes Dev. , vol.14 , pp. 3140-3152
    • Collins, R.T.1    Treisman, J.E.2
  • 33
    • 0036828797 scopus 로고    scopus 로고
    • Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors
    • Inoue H., Furukawa T., Giannakopoulos S., Zhou S., King D.S., and Tanese N. Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors. J Biol Chem 277 (2002) 41674-41685
    • (2002) J Biol Chem , vol.277 , pp. 41674-41685
    • Inoue, H.1    Furukawa, T.2    Giannakopoulos, S.3    Zhou, S.4    King, D.S.5    Tanese, N.6
  • 34
    • 0034461148 scopus 로고    scopus 로고
    • A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex
    • Nie Z., Xue Y., Yang D., Zhou S., Deroo B.J., Archer T.K., and Wang W. A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol Cell Biol 20 (2000) 8879-8888
    • (2000) Mol Cell Biol , vol.20 , pp. 8879-8888
    • Nie, Z.1    Xue, Y.2    Yang, D.3    Zhou, S.4    Deroo, B.J.5    Archer, T.K.6    Wang, W.7
  • 35
    • 0343091991 scopus 로고    scopus 로고
    • The Drosophila Brahma complex is an essential coactivator for the trithorax group protein Zeste
    • Kal A.J., Mahmoudi T., Zak N.B., and Verrijzer C.P. The Drosophila Brahma complex is an essential coactivator for the trithorax group protein Zeste. Genes Dev 14 (2000) 1058-1071
    • (2000) Genes Dev , vol.14 , pp. 1058-1071
    • Kal, A.J.1    Mahmoudi, T.2    Zak, N.B.3    Verrijzer, C.P.4
  • 36
    • 0037337584 scopus 로고    scopus 로고
    • Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa
    • Heitzler P., Vanolst L., Biryukova I., and Ramain P. Enhancer-promoter communication mediated by Chip during Pannier-driven proneural patterning is regulated by Osa. Genes Dev 17 (2003) 591-596
    • (2003) Genes Dev , vol.17 , pp. 591-596
    • Heitzler, P.1    Vanolst, L.2    Biryukova, I.3    Ramain, P.4
  • 37
    • 0036176172 scopus 로고    scopus 로고
    • Transcription activator interactions with multiple SWI/SNF subunits
    • Neely K.E., Hassan A.H., Brown C.E., Howe L., and Workman J.L. Transcription activator interactions with multiple SWI/SNF subunits. Mol Cell Biol 22 (2002) 1615-1625
    • (2002) Mol Cell Biol , vol.22 , pp. 1615-1625
    • Neely, K.E.1    Hassan, A.H.2    Brown, C.E.3    Howe, L.4    Workman, J.L.5
  • 38
    • 33745466304 scopus 로고    scopus 로고
    • Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation
    • Zhang X., Azhar G., Zhong Y., and Wei J.Y. Zipzap/p200 is a novel zinc finger protein contributing to cardiac gene regulation. Biochem Biophys Res Commun 346 (2006) 794-801
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 794-801
    • Zhang, X.1    Azhar, G.2    Zhong, Y.3    Wei, J.Y.4
  • 39
    • 27644580861 scopus 로고    scopus 로고
    • The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis
    • This paper shows that a mutation in the NURF subunit NURF301 prevents pupariation and specifically disrupts the expression of target genes of the ecdysone receptor. The NURF complex also physically interacts with the receptor in a ligand-dependent manner.
    • Badenhorst P., Xiao H., Cherbas L., Kwon S.Y., Voas M., Rebay I., Cherbas P., and Wu C. The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. Genes Dev 19 (2005) 2540-2545. This paper shows that a mutation in the NURF subunit NURF301 prevents pupariation and specifically disrupts the expression of target genes of the ecdysone receptor. The NURF complex also physically interacts with the receptor in a ligand-dependent manner.
    • (2005) Genes Dev , vol.19 , pp. 2540-2545
    • Badenhorst, P.1    Xiao, H.2    Cherbas, L.3    Kwon, S.Y.4    Voas, M.5    Rebay, I.6    Cherbas, P.7    Wu, C.8
  • 40
    • 41149139269 scopus 로고    scopus 로고
    • The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity
    • Kwon S.Y., Xiao H., Glover B.P., Tjian R., Wu C., and Badenhorst P. The nucleosome remodeling factor (NURF) regulates genes involved in Drosophila innate immunity. Dev Biol 316 (2008) 538-547
    • (2008) Dev Biol , vol.316 , pp. 538-547
    • Kwon, S.Y.1    Xiao, H.2    Glover, B.P.3    Tjian, R.4    Wu, C.5    Badenhorst, P.6
  • 42
    • 44949144048 scopus 로고    scopus 로고
    • CHD8 is an ATP-dependent chromatin remodeling factor that regulates {beta}-catenin target genes
    • Thompson B.A., Tremblay V., Lin G., and Bochar D.A. CHD8 is an ATP-dependent chromatin remodeling factor that regulates {beta}-catenin target genes. Mol Cell Biol 28 (2008) 3894-3904
    • (2008) Mol Cell Biol , vol.28 , pp. 3894-3904
    • Thompson, B.A.1    Tremblay, V.2    Lin, G.3    Bochar, D.A.4
  • 43
    • 0037178788 scopus 로고    scopus 로고
    • Evidence for a Mediator of RNA polymerase II transcriptional regulation conserved from yeast to man
    • Boube M., Joulia L., Cribbs D.L., and Bourbon H.M. Evidence for a Mediator of RNA polymerase II transcriptional regulation conserved from yeast to man. Cell 110 (2002) 143-151
    • (2002) Cell , vol.110 , pp. 143-151
    • Boube, M.1    Joulia, L.2    Cribbs, D.L.3    Bourbon, H.M.4
  • 45
    • 0035834772 scopus 로고    scopus 로고
    • The structural and functional organization of the yeast Mediator complex
    • Kang J.S., Kim S.H., Hwang M.S., Han S.J., Lee Y.C., and Kim Y.J. The structural and functional organization of the yeast Mediator complex. J Biol Chem 276 (2001) 42003-42010
    • (2001) J Biol Chem , vol.276 , pp. 42003-42010
    • Kang, J.S.1    Kim, S.H.2    Hwang, M.S.3    Han, S.J.4    Lee, Y.C.5    Kim, Y.J.6
  • 46
    • 34247100676 scopus 로고    scopus 로고
    • Med19(Rox3) regulates intermodule interactions in the Saccharomyces cerevisiae Mediator complex
    • Baidoobonso S.M., Guidi B.W., and Myers L.C. Med19(Rox3) regulates intermodule interactions in the Saccharomyces cerevisiae Mediator complex. J Biol Chem 282 (2007) 5551-5559
    • (2007) J Biol Chem , vol.282 , pp. 5551-5559
    • Baidoobonso, S.M.1    Guidi, B.W.2    Myers, L.C.3
  • 47
    • 33646829646 scopus 로고    scopus 로고
    • Role of the Mediator complex in nuclear hormone receptor signaling
    • Belakavadi M., and Fondell J.D. Role of the Mediator complex in nuclear hormone receptor signaling. Rev Physiol Biochem Pharmacol 156 (2006) 23-43
    • (2006) Rev Physiol Biochem Pharmacol , vol.156 , pp. 23-43
    • Belakavadi, M.1    Fondell, J.D.2
  • 48
    • 0037043739 scopus 로고    scopus 로고
    • A component of the ARC/Mediator complex required for TGF beta/Nodal signalling
    • Kato Y., Habas R., Katsuyama Y., Naar A.M., and He X. A component of the ARC/Mediator complex required for TGF beta/Nodal signalling. Nature 418 (2002) 641-646
    • (2002) Nature , vol.418 , pp. 641-646
    • Kato, Y.1    Habas, R.2    Katsuyama, Y.3    Naar, A.M.4    He, X.5
  • 49
    • 0033587187 scopus 로고    scopus 로고
    • Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein
    • This was one of the first papers to show that a specific Mediator subunit is involved in signal transduction by binding to the Elk-1 transcription factor once it has been phosphorylated by the ERK kinase.
    • Boyer T.G., Martin M.E., Lees E., Ricciardi R.P., and Berk A.J. Mammalian Srb/Mediator complex is targeted by adenovirus E1A protein. Nature 399 (1999) 276-279. This was one of the first papers to show that a specific Mediator subunit is involved in signal transduction by binding to the Elk-1 transcription factor once it has been phosphorylated by the ERK kinase.
    • (1999) Nature , vol.399 , pp. 276-279
    • Boyer, T.G.1    Martin, M.E.2    Lees, E.3    Ricciardi, R.P.4    Berk, A.J.5
  • 50
    • 44349194208 scopus 로고    scopus 로고
    • Pygopus activates Wingless target gene transcription through the Mediator complex subunits Med12 and Med13
    • Carrera I., Janody F., Leeds N., Duveau F., and Treisman J.E. Pygopus activates Wingless target gene transcription through the Mediator complex subunits Med12 and Med13. Proc Natl Acad Sci U S A 105 (2008) 6644-6649
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 6644-6649
    • Carrera, I.1    Janody, F.2    Leeds, N.3    Duveau, F.4    Treisman, J.E.5
  • 51
    • 33646580781 scopus 로고    scopus 로고
    • Mediator is a transducer of Wnt/beta-catenin signaling
    • Kim S., Xu X., Hecht A., and Boyer T.G. Mediator is a transducer of Wnt/beta-catenin signaling. J Biol Chem 281 (2006) 14066-14075
    • (2006) J Biol Chem , vol.281 , pp. 14066-14075
    • Kim, S.1    Xu, X.2    Hecht, A.3    Boyer, T.G.4
  • 52
    • 33845219533 scopus 로고    scopus 로고
    • Mediator modulates Gli3-dependent Sonic hedgehog signaling
    • Zhou H., Kim S., Ishii S., and Boyer T.G. Mediator modulates Gli3-dependent Sonic hedgehog signaling. Mol Cell Biol 26 (2006) 8667-8682
    • (2006) Mol Cell Biol , vol.26 , pp. 8667-8682
    • Zhou, H.1    Kim, S.2    Ishii, S.3    Boyer, T.G.4
  • 53
    • 28544440730 scopus 로고    scopus 로고
    • Activation of TRAP/Mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation
    • This paper shows that phosphorylation of the Mediator complex subunit MED1 by MAP kinase regulates its levels, subnuclear localization and coactivation strength.
    • Pandey P.K., Udayakumar T.S., Lin X., Sharma D., Shapiro P.S., and Fondell J.D. Activation of TRAP/Mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylation. Mol Cell Biol 25 (2005) 10695-10710. This paper shows that phosphorylation of the Mediator complex subunit MED1 by MAP kinase regulates its levels, subnuclear localization and coactivation strength.
    • (2005) Mol Cell Biol , vol.25 , pp. 10695-10710
    • Pandey, P.K.1    Udayakumar, T.S.2    Lin, X.3    Sharma, D.4    Shapiro, P.S.5    Fondell, J.D.6
  • 54
    • 44949188489 scopus 로고    scopus 로고
    • MED1 phosphorylation promotes its association with Mediator: implications for nuclear receptor signaling
    • Belakavadi M., Pandey P.K., Vijayvargia R., and Fondell J.D. MED1 phosphorylation promotes its association with Mediator: implications for nuclear receptor signaling. Mol Cell Biol 28 (2008) 3932-3942
    • (2008) Mol Cell Biol , vol.28 , pp. 3932-3942
    • Belakavadi, M.1    Pandey, P.K.2    Vijayvargia, R.3    Fondell, J.D.4
  • 55
    • 3042760385 scopus 로고    scopus 로고
    • The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus
    • Chang Y.W., Howard S.C., and Herman P.K. The Ras/PKA signaling pathway directly targets the Srb9 protein, a component of the general RNA polymerase II transcription apparatus. Mol Cell 15 (2004) 107-116
    • (2004) Mol Cell , vol.15 , pp. 107-116
    • Chang, Y.W.1    Howard, S.C.2    Herman, P.K.3
  • 56
    • 0037039776 scopus 로고    scopus 로고
    • Structure, function, and activator-induced conformations of the CRSP coactivator
    • Electron microscopic structural studies show that binding of two different activators to the Mediator complex induces distinct conformational changes.
    • Taatjes D.J., Naar A.M., Andel III F., Nogales E., and Tjian R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295 (2002) 1058-1062. Electron microscopic structural studies show that binding of two different activators to the Mediator complex induces distinct conformational changes.
    • (2002) Science , vol.295 , pp. 1058-1062
    • Taatjes, D.J.1    Naar, A.M.2    Andel III, F.3    Nogales, E.4    Tjian, R.5
  • 57
    • 8844229536 scopus 로고    scopus 로고
    • Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover
    • Fryer C.J., White J.B., and Jones K.A. Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover. Mol Cell 16 (2004) 509-520
    • (2004) Mol Cell , vol.16 , pp. 509-520
    • Fryer, C.J.1    White, J.B.2    Jones, K.A.3
  • 58
    • 0034678610 scopus 로고    scopus 로고
    • The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates
    • Hecht A., Vleminckx K., Stemmler M.P., van Roy F., and Kemler R. The p300/CBP acetyltransferases function as transcriptional coactivators of beta-catenin in vertebrates. EMBO J 19 (2000) 1839-1850
    • (2000) EMBO J , vol.19 , pp. 1839-1850
    • Hecht, A.1    Vleminckx, K.2    Stemmler, M.P.3    van Roy, F.4    Kemler, R.5
  • 59
    • 0032527756 scopus 로고    scopus 로고
    • TGF-beta-stimulated cooperation of Smad proteins with the coactivators CBP/p300
    • Janknecht R., Wells N.J., and Hunter T. TGF-beta-stimulated cooperation of Smad proteins with the coactivators CBP/p300. Genes Dev 12 (1998) 2114-2119
    • (1998) Genes Dev , vol.12 , pp. 2114-2119
    • Janknecht, R.1    Wells, N.J.2    Hunter, T.3
  • 60
    • 0036606776 scopus 로고    scopus 로고
    • Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex
    • Fryer C.J., Lamar E., Turbachova I., Kintner C., and Jones K.A. Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex. Genes Dev 16 (2002) 1397-1411
    • (2002) Genes Dev , vol.16 , pp. 1397-1411
    • Fryer, C.J.1    Lamar, E.2    Turbachova, I.3    Kintner, C.4    Jones, K.A.5
  • 61
    • 0033969466 scopus 로고    scopus 로고
    • Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo
    • Chen Y., Goodman R.H., and Smolik S.M. Cubitus interruptus requires Drosophila CREB-binding protein to activate wingless expression in the Drosophila embryo. Mol Cell Biol 20 (2000) 1616-1625
    • (2000) Mol Cell Biol , vol.20 , pp. 1616-1625
    • Chen, Y.1    Goodman, R.H.2    Smolik, S.M.3
  • 62
    • 0033520422 scopus 로고    scopus 로고
    • Stat protein transactivation domains recruit p300/CBP through widely divergent sequences
    • Paulson M., Pisharody S., Pan L., Guadagno S., Mui A.L., and Levy D.E. Stat protein transactivation domains recruit p300/CBP through widely divergent sequences. J Biol Chem 274 (1999) 25343-25349
    • (1999) J Biol Chem , vol.274 , pp. 25343-25349
    • Paulson, M.1    Pisharody, S.2    Pan, L.3    Guadagno, S.4    Mui, A.L.5    Levy, D.E.6
  • 63
    • 0037439199 scopus 로고    scopus 로고
    • MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300
    • Li Q.J., Yang S.H., Maeda Y., Sladek F.M., Sharrocks A.D., and Martins-Green M. MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300. EMBO J 22 (2003) 281-291
    • (2003) EMBO J , vol.22 , pp. 281-291
    • Li, Q.J.1    Yang, S.H.2    Maeda, Y.3    Sladek, F.M.4    Sharrocks, A.D.5    Martins-Green, M.6
  • 64
    • 34547902154 scopus 로고    scopus 로고
    • Orchestration of chromatin-based processes: mind the TRRAP
    • Murr R., Vaissiere T., Sawan C., Shukla V., and Herceg Z. Orchestration of chromatin-based processes: mind the TRRAP. Oncogene 26 (2007) 5358-5372
    • (2007) Oncogene , vol.26 , pp. 5358-5372
    • Murr, R.1    Vaissiere, T.2    Sawan, C.3    Shukla, V.4    Herceg, Z.5
  • 65
    • 7044250740 scopus 로고    scopus 로고
    • Lysine acetylation and the bromodomain: a new partnership for signaling
    • Yang X.J. Lysine acetylation and the bromodomain: a new partnership for signaling. Bioessays 26 (2004) 1076-1087
    • (2004) Bioessays , vol.26 , pp. 1076-1087
    • Yang, X.J.1
  • 67
    • 0032189630 scopus 로고    scopus 로고
    • Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling
    • This paper was an early demonstration that CBP has non-histone targets; in this case acetylation of TCF by CBP reduces its ability to bind to β-catenin and activate transcription.
    • Waltzer L., and Bienz M. Drosophila CBP represses the transcription factor TCF to antagonize Wingless signalling. Nature 395 (1998) 521-525. This paper was an early demonstration that CBP has non-histone targets; in this case acetylation of TCF by CBP reduces its ability to bind to β-catenin and activate transcription.
    • (1998) Nature , vol.395 , pp. 521-525
    • Waltzer, L.1    Bienz, M.2
  • 68
    • 0037067691 scopus 로고    scopus 로고
    • Acetylation of beta-catenin by CREB-binding protein (CBP)
    • Wolf D., Rodova M., Miska E.A., Calvet J.P., and Kouzarides T. Acetylation of beta-catenin by CREB-binding protein (CBP). J Biol Chem 277 (2002) 25562-25567
    • (2002) J Biol Chem , vol.277 , pp. 25562-25567
    • Wolf, D.1    Rodova, M.2    Miska, E.A.3    Calvet, J.P.4    Kouzarides, T.5
  • 70
    • 34047248402 scopus 로고    scopus 로고
    • Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB
    • This paper demonstrates that post-translational modification of CBP is a route for crosstalk between pathways. Phosphorylation of CBP by IKKα increases its binding to NF-κB and reduces its binding to p53.
    • Huang W.C., Ju T.K., Hung M.C., and Chen C.C. Phosphorylation of CBP by IKKalpha promotes cell growth by switching the binding preference of CBP from p53 to NF-kappaB. Mol Cell 26 (2007) 75-87. This paper demonstrates that post-translational modification of CBP is a route for crosstalk between pathways. Phosphorylation of CBP by IKKα increases its binding to NF-κB and reduces its binding to p53.
    • (2007) Mol Cell , vol.26 , pp. 75-87
    • Huang, W.C.1    Ju, T.K.2    Hung, M.C.3    Chen, C.C.4
  • 71
    • 56049106473 scopus 로고    scopus 로고
    • Carrera, Zavadil and Treisman, 2008, Mol. Cell. Biol. [Epub ahead of print].
    • Carrera, Zavadil and Treisman, 2008, Mol. Cell. Biol. [Epub ahead of print].


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.