Adaptive antioxidant methionine accumulation in respiratory chain complexes explains the use of a deviant genetic code in mitochondria

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 43, 2008, Pages 16496-16501

  Bender, Aline ^a   Hajievab, Parvana ^a   Moosmann, Bernd ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Evolution; Methionine sulfoxide; Nonstandard genetic code; Oxidative stress; Protein oxidation

Indexed keywords

ANTIOXIDANT; CYTOCHROME B; ISOLEUCINE; METHIONINE; PROTEOME; REACTIVE OXYGEN METABOLITE;

AMINO ACID SUBSTITUTION; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CODON; CONTROLLED STUDY; GENETIC CODE; MITOCHONDRIAL MEMBRANE; MOLECULAR EVOLUTION; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN STRUCTURE; RAT; RESPIRATORY CHAIN;

ANIMALS; ANTIOXIDANTS; DATABASES, NUCLEIC ACID; DNA, MITOCHONDRIAL; ELECTRON TRANSPORT; EVOLUTION; FUNGI; GENETIC CODE; GENOME; ISOLEUCINE; METHIONINE; MITOCHONDRIAL MEMBRANES; OXIDATIVE STRESS; PLANTS;

ANIMALIA;

EID: 55949132715     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802779105     Document Type: Article

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