TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 44, 2008, Pages 17181-17186

  Zhou, Xiu Ping ^a   Wu, Kong Yan ^a   Liang, Bin ^a   Fu, Xiu Qing ^a   Luo, Zhen Ge ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

BDNF; Dendrite; Neuronal activity; Prenylation; Rac

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GERANYLTRANSFERASE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DENDRITE; EMBRYO; ENZYME ACTIVATION; MEMBRANE DEPOLARIZATION; MORPHOGENESIS; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RAT;

ALKYL AND ARYL TRANSFERASES; ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; DENDRITES; HUMANS; MICE; MICE, INBRED ICR; MORPHOGENESIS; NEURONS; PRENYLATION; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; TRANSFECTION;

MUS;

EID: 55949115388     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0800846105     Document Type: Article

References (52)

1. Jan YN, Jan LY (2003) The control of dendrite development. Neuron 40:229-242.
2. Chen Y, Ghosh A (2005) Regulation of dendritic development by neuronal activity. J Neurobiol 64:4-10.
3. Konur S, Ghosh A (2005) Calcium signaling and the control of dendritic development. Neuron 46:401-405.
4. McAllister AK, Katz LC, Lo DC (1997) Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth. Neuron 18:767-778.
5. Gorski JA, Zeiler SR, Tamowski S, Jones KR (2003) Brain-derived neurotrophic factor is required for the maintenance of cortical dendrites. J Neurosci 23:6856-6865.
6. Gaudilliere B, Konishi Y, de la Iglesia N, Yao G, Bonni A (2004) A CaMKII-NeuroD signaling pathway specifies dendritic morphogenesis. Neuron 4:229-241.
7. Redmond L, Kashani AH, Ghosh A (2002) Calcium regulation of dendritic growth via CaM kinase IV and CREB-mediated transcription. Neuron 34:999-1010.
8. Li Z, Van Aelst L, Cline HT (2000) Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nat Neurosci 3:217-225.
9. Li Z, Aizenman CD, Cline HT (2002) Regulation of rho GTPases by crosstalk and neuronal activity in vivo. Neuron 33:741-750.
10. Ruchhoeft ML, Ohnuma S, McNeill L, Holt CE, Harris WA (1999) The neuronal architecture of Xenopus retinal ganglion cells is sculpted by rho-family GTPases in vivo. J Neurosci 19:8454-8463.
11. Lee T, Winter C, Marticke SS, Lee A, Luo L (2000) Essential roles of Drosophila RhoA in the regulation of neuroblast proliferation and dendritic but not axonal morphogenesis. Neuron 25:307-316.
12. Sin WC, Haas K, Ruthazer ES, Cline HT (2002) Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases. Nature 419:475-480.
13. Miyamoto Y, Yamauchi J, Tanoue A, Wu C, Mobley WC (2006) TrkB binds and tyrosine-phosphorylates Tiam1, leading to activation of Rac1 and induction of changes in cellular morphology. Proc Natl Acad Sci USA 103:10444-10449.
14. Hall A (1998) Rho GTPases and the actin cytoskeleton. Science 279:509-514.
15. Schmidt A, Hall A (2002) Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev 16:1587-1609.
16. Hancock JF, Magee AI, Childs JE, Marshall CJ (1989) All ras proteins are polyisoprenylated but only some are palmitoylated. Cell 57:1167-1177.
17. Philips MR, et al. (1993) Carboxyl methylation of Ras-related proteins during signal transduction in neutrophils. Science 259:977-980.
18. Zhang FL, Casey PJ (1996) Protein prenylation: molecular mechanisms and functional consequences. Annu Rev Biochem 65:241-269.
19. Luo ZG, et al. (2003) Implication of geranylgeranyltransferase I in synapse formation. Neuron 40:703-717.
20. Yokoyama K, Goodwin GW, Ghomashchi F, Glomset JA, Gelb MH (1991) A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity. Proc Natl Acad Sci USA 88:5302-5306.
21. Ericsson J, et al. (1993) Distribution of prenyltransferases in rat tissues. Evidence for a cytosolic all-trans-geranylgeranyl diphosphate synthase. J Biol Chem 268:832-838.
22. Niblock MM, Brunso-Bechtold JK, Riddle DR (2000) Insulin-like growth factor I stimulates dendritic growth in primary somatosensory cortex. J Neurosci 20:4165-4176.
23. Chappell J, et al. Potentiation of Rho-A-mediated lysophosphatidic acid activity by hyperinsulinemia. J Biol Chem 275:31792-31797, 2000.
24. Goalstone ML, et al. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. J Biol Chem 276:12805-12812, 2001.
25. Threadgill R, Bobb K, Ghosh A (1997) Regulation of dendritic growth and remodeling by Rho, Rac, and Cdc42. Neuron 19:625-634.
26. Luo L (2002) Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticity. Annu Rev Cell Dev Biol 18:601-635.
27. del Pozo MA, Price LS, Alderson NB, Ren XD, Schwartz MA (2000) Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK. EMBO J 19:2008-2014.,
28. Guzowski JF, McNaughton BL, Barnes CA, Worley PF (1999) Environment-specific expression of the immediate-early gene Arc in hippocampal neuronal ensembles. Nat Neurosci 2:1120-1124.
29. Ramanan N, et al. (2005) SRF mediates activity-induced gene expression and synaptic plasticity but not neuronal viability. Nat Neurosci 8:759-767.
30. Vazdarjanova A, McNaughton BL, Barnes CA, Worley PF, Guzowski JF (2002) Experience-dependent coincident expression of the effector immediate-early genes arc and Homer 1a in hippocampal and neocortical neuronal networks. J Neurosci 22:10067-10071.
31. Abe K, Takeichi M (2007) NMDA-receptor activation induces calpain-mediated beta-catenin cleavages for triggering gene expression. Neuron 53:387-397.
32. Szebenyi G, et al. (2005) Activity-driven dendritic remodeling requires microtubule-associated protein 1A. Curr Biol 15:1820-1826.
33. Yu X, Malenka RC (2003) Beta-catenin is critical for dendritic morphogenesis. Nat Neurosci 6:1169-1177.
34. Labelle C, Leclerc N (2000) Exogenous BDNF, NT-3 and NT-4 differentially regulate neurite outgrowth in cultured hippocampal neurons. Brain Res Dev Brain Res 123:1-11.
35. McAllister AK, Katz LC, Lo DC (1996) Neurotrophin regulation of cortical dendritic growth requires activity. Neuron 17:1057-1064.
36. Andres DA, Goldstein JL, Ho YK, Brown MS (1993) Mutational analysis of alpha-subunit of protein farnesyltransferase: evidence for a catalytic role. J Biol Chem 268:1383-1390.
37. Wu Z, et al. (1999) Farnesyl protein transferase: identification of K164 alpha and Y300 beta as catalytic residues by mutagenesis and kinetic studies. Biochemistry 38:11239-11249.
38. Zhang JM, et al. (2003) ATP released by astrocytes mediates glutamatergic activity-dependent heterosynaptic suppression. Neuron 40:971-982.
39. el-Husseini Ael D, Bredt DS (2002) Protein palmitoylation: a regulator of neuronal development and function. Nat Rev Neurosci 3:791-802.
40. Resh MD (2006) Trafficking and signaling by fatty-acylated and prenylated proteins. Nat Chem Biol 2:584-590.
41. Si Sinensky M (2000) Recent advances in the study of prenylated proteins. Biochim Biophys Acta 1484:93-106.
42. Takemoto-Kimura S, et al. (2007) Regulation of dendritogenesis via a lipid-raft-associated Ca2+/calmodulin-dependent protein kinase CLICK-III/CaMKIgamma. Neuron 54:755-770.
43. Doye A, et al. (2002) CNF1 exploits the ubiquitin-proteasome machinery to restrict Rho GTPase activation for bacterial host cell invasion. Cell 111:553-564.
44. Van Aelst L, Cline HT (2004) Rho GTPases and activity-dependent dendrite development. Curr Opin Neurobiol 14:297-304.
45. Estrach S, et al. (2002) The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth. Curr Biol 12:307-312.
46. Tolias KF, et al. (2005) The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron 45:525-538.
47. Huang YZ, Pan E, Xiong ZQ, McNamara JO (2008) Zinc-mediated transactivation of TrkB potentiates the hippocampal mossy fiber-CA3 pyramid synapse. Neuron 57:546-558.
48. Chen YM, et al. (2006) Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity. Proc Natl Acad Sci USA 103:8534-8539.
49. Xia Z, Dudek H, Miranti CK, Greenberg ME (1996) Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism. J Neurosci 16:5425-5436.
50. Luo ZG, et al. (2002) Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1. Neuron 35:489-505.
51. Pickett WC, et al. (1995) A fluorescence assay for geranylgeranyl transferase type I. Anal Biochem 225:60-63.
52. Goossens L, Deweer S, Pommery J, Henichart JP, Goossens JF (2005) Spectroscopic study of fluorescent peptides for prenyl transferase assays. J Pharm Biomed Anal 37:417-422.