Chemical compositions responsible for inflammation and tissue damage in the mouse lung by coarse and fine particulate samples from contrasting air pollution in Europe

Inhalation Toxicology

Volumn 20, Issue 14, 2008, Pages 1215-1231

  Happo, Mikko S ^a,b   Hirvonen, Maija Riitta ^a   Halinen, Arja I ^b   Jalava, Pasi I ^a   Pennanen, Arto S ^b   Sillanpaa, Markus ^c   Hillamo, Risto ^c   Salonen, Raimo O ^b  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^c FINNISH METEOROLOGICAL INSTITUTE   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ACID ANHYDRIDE; ALUMINUM; AMMONIA; ARSENIC; CALCIUM; CHLORIDE; COAL; CYTOKINE; DICARBOXYLIC ACID; INTERLEUKIN 6; IRON; MONOSACCHARIDE ANHYDRIDE DERIVATIVE; NICKEL; NITRATE; ORGANIC COMPOUND; POLYCYCLIC AROMATIC HYDROCARBON; POTASSIUM; SILICON; SULFATE; TRANSITION ELEMENT; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VANADIUM;

AIR POLLUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMASS; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; COMBUSTION; CONTROLLED STUDY; DUST; EUROPE; LUNG INJURY; LUNG LAVAGE; LUNG TOXICITY; MALE; MOUSE; NONHUMAN; PARTICULATE MATTER; PNEUMONIA; PRIORITY JOURNAL; TISSUE INJURY;

AIR POLLUTANTS; AIR POLLUTION; ANIMALS; EUROPE; FUEL OILS; MALE; METALS; MICE; MICE, INBRED C57BL; ORGANIC CHEMICALS; PARTICLE SIZE; PARTICULATE MATTER; VEHICLE EMISSIONS;

MUS;

EID: 55949097651     PISSN: 08958378     EISSN: 10917691     Source Type: Journal    
DOI: 10.1080/08958370802147282     Document Type: Article

References (63)

1. Alexis, N. E., Lay, J. C., Zeman, K., Bennett, W. E., Peden, D. B., Soukup, J. M., Devlin, R. B., and Becker, S. 2006. Biological material on inhaled coarse fraction particulate matter activates airway phagocytes in vivo in healthy volunteers. J. Allergy Clin. Immunol. 117:1396-1403.
2. 3). Report EUR/04/5042688 of a WHO task group. Copenhagen, Denmark: WHO Regional Office for Europe.
3. Becher, R., Hetland, R. B., Refsnes, M., Dahl, J. E., Dahlman, H. J., and Schwarze, P. E. 2001. Rat lung inflammatory responses after in vivo and in vitro exposure to various stone particles. Inhal. Toxicol. 13:789-805.
4. Becker, S., Soukup, J. M., Sioutas, C., and Cassee, F. 2003. Response of human alveolar macrophages to ultrafine, fine and coarse urban air pollution particles. Exp. Lung Res. 29:29-44.
5. Brewer P. G. 1975. Minor elements in sea water. In Chemical oceanography, ed. R. Chester, Vol. 1, pp. 417-425. San Diego: Academic.
6. Boman, B. C., Forsberg, A. B,. and Järvholm, B. G. 2003. Adverse health effects from air pollution in relation to residential wood combustion in modern society. Scand. J. Work Environ. Health 29:251-260.
7. 2.5, and inorganic constituents of atmospheric particulate matter at multiple Canadian locations. J. Air Waste Manage. Assoc. 47:2-19.
8. Brunekreef, B., and Forsberg, B. 2005. Epidemiological evidence of effects of coarse airborne particles on health. Eur. Respir. J. 26:309-318.
9. Burnett, R. T., Brook, J., Dann, T., Delocla, C., Philips, O., Goldberg, M. S., and Krewski, D. 2000. Association between particulate- and gas-phase components of urban air pollution and daily mortality in eight Canadian cities. Inhal. Toxicol. 12(suppl. 4):15-39.
10. Clancy, L., Goodman, P., Sinclair, H., and Dockery, D. W. 2002. Effect of air-pollution control on death rates in Dublin, Ireland: An intervention study. Lancet 360:1210-1214.
11. Costa, D. L., Lehmann, J. R., Winsett, D., Richards, J., Ledbetter, A. D., and Dreher, K. L. 2006. Comparative pulmonary toxicological assessment of oil combustion particles following inhalation or instillation exposure. Toxicol. Sci. 91:237-246.
12. Driscoll, K. E., Costa, D. L., Hatch, G., Henderson, R., Oberdörster, G., Salem, H., and Schlesinger, R. B. 2000. Intratracheal instillation as an exposure technique for the evaluation of respiratory tract toxicity: Uses and limitations. Toxicol. Sci. 55:24-35.
13. Dye, J. A., Lehmann, J. R., McGee, J. K., Winsett, D. W., Ledbetter, A. D., Everitt, J. I., Ghio, A. J., and Costa, D. L. 2001. Acute pulmonary toxicity of particulate matter filter extracts in rats: Coherence with epidemiological studies in Utah Valley residents. Environ. Health Perspect. 109:395-403.
14. European Union. 2004. Directive 2004/107/EC of the European Parliament and of the Council of 15 December 2004 relating to arsenic, cadmium, mercury, nickel and polycyclic aromatic hydrocarbons in ambient air. Official Journal L 23, 26/01/2005.
15. Gavett, S. H., Madison, S. L, Dreher, K. L., Winsett, D. W., McGee, J. K., and Costa D. L. 1997. Metal and sulfate composition of residual oil fly ash determines airway hyperreactivity and lung injury in rats. Environ. Res. 72:162-172.
16. 2.5. Toxicol. In Vitro 20:575-584.
17. Ghanem, M. M., Battelli, L. A., Mercer R. R., Scabilloni, J. F., Kashon, M. L., Ma, J. Y. C., Nath, J., and Hubbs, A. F. 2006. Apoptosis and Bax expression are increased by coal dust in the polycyclic aromatic hydrocarbon-exposed lung. Environ. Health Perspect. 114:1367-1373.
18. Ghio, A. J., Kennedy, T. P., Whorton, A. R., Crumbliss, A. L., Hatch, G. E., and Hoidal, J. R. 1992. Role of surface complexed iron in oxidant generation and lung inflammation induced by silicates. Am. J. Physiol. 263:511-518.
19. Ghio, A. J. 2004. Biological effects of Utah Valley ambient air particles in humans: A review. J. Aerosol. Med. 17:157-164.
20. Happo, M. S., Salonen, R. O., Hälinen, A. I., Jalava, P. I., Pennanen, A. S., Kosma, V. M., Sillanpää, M., Hillamo, R., Brunekreef, B., Katsouyanni, K., Sunyer, J., and Hirvonen, M.-R. 2007. Dose- and time-dependency of inflammatory responses in the mouse lung to urban air coarse, fine and ultrafine particles from six European cities. Inhal. Toxicol. 19:227-246.
21. Hetland, R. B., Refsnes, M., Myran, T., Johansen, B. V., Uthus, B., and Schwarze, P. E. 2000. Mineral and/or metal content as critical determinants of particle-induced release of IL-6 and IL-8 from A549 cells. J. Toxicol. Environ. Health A 60:47-65.
22. Hoek, G., Brunekreef, B., Goldbohm, S., Fischer, P., and van den Brandt, P. A. 2002. Association between mortality and indicators of traffic-related air pollution in Netherlands: A cohort study. Lancet 360:1203-1209.
23. Hollander, A., Heederik, D., Versloot, P., and Douwes, J. 1993. Inhibition and enhancement in the analysis of airborne endotoxin levels in various occupational environments. Am. Ind. Hyg. Assoc. J. 54:647-653.
24. Holopainen, M., Hirvonen, M.-R., Komulainen, H., and Klockars, M. 2004. Effect of shape of mica particles on the production of tumor necrosis factor alpha in mouse macrophages. Scand. J. Work Environ. Health 2:91-98.
25. 10 metal composition and ability to induce inflammation. Respir. Res. 6:43.
26. Jalava, P., Salonen, R. O., Hälinen, A. I., Sillanpää, M., Sandell, E., and Hirvonen, M.-R. 2005. Effects of sample preparation on chemistry, cytotoxicity, and inflammatory responses induced by air particulate matter. Inhal. Toxicol. 17:107-117.
27. Jalava, P. I., Salonen, R. O., Hälinen, A. I., Penttinen, P., Pennanen, A. S., Sillanpää, M., Sandell, E., Hillamo, R., and Hirvonen, M.-R. 2006. In vitro inflammatory and cytotoxic effects of size-segregated particulate samples collected during long-range transport of wildfire smoke to Helsinki. Toxicol. Appl. Pharmacol. 215:341-353.
28. Jalava, P. I., Salonen R. O., Pennanen, A. S., Sillanpää, M., Hälinen, A. I., Happo, M. S., Hillamo, R., Brunekreef, B., Katsouyanni, K., Sunyer, J., and Hirvonen, M.-R. 2007. Heterogeneities in inflammatory and cytotoxic responses of RAW 264.7 macrophage cell line to urban air coarse, fine and ultrafine particles from six European sampling campaigns. Inhal. Toxicol. 19:213-225.
29. Janssen, N. A. H., Brunekreef, B., van Vliet, P., Aarts, F., Meliefste, K., Harssema, H., and Fischer, P. 2003. The relationship between air pollution from heavy traffic and allergic sensitization, bronchial hyperresponsiveness, and respiratory symptoms in Dutch schoolchildren. Environ. Health Perspect. 111:1512-1518.
30. Jones, A. M., and Harrison, R. M. 2004. The effects of meteorological factors on atmospheric bioaerosol concentrations - A review. Sci. Total Environ. 326:151-180.
31. Jussila, J., Komulainen, H., Huttunen, K., Roponen, M., Hälinen, A., Hyvärinen, A., Kosma, V.-M., Pelkonen, J., and Hirvonen, M.-R. 2001. Inflammatory responses in mice after intratracheal instillation of spores of Streptomyces californicus isolated from indoor air of moldy building. Toxicol. Appl. Pharmacol. 171:61-69.
32. Kawamura, K., and Ikushima, K. 1993. Seasonal changes in the distribution of dicarboxylic acids in the urban atmosphere. Environ. Sci. Technol. 27:2227-2235.
33. Kerminen, V.-M., Teinilä, K., Hillamo, R., and Pakkanen, T. 1998. Substitution of chloride in sea-salt particles by inorganic and organic anions. J. Aerosol Sci. 29:929-942.
34. Kong, L-Y., Luster, M. I., Dixon, D., O'Grady, J., and Rosenthal, G. J. 1994. Inhibition of lung immunity after intratracheal instillation of benzo(a)pyrene. Am. J. Respir. Crit. Care Med. 150:1123-1129.
35. Lanki, T., de Hartog, J. J., Heinrich, J., Hoek, G., Janssen, N. A. H., Peters, A., Stölzel, M., Timonen, K. L., Vallius, M., Vanninen, E., and Pekkanen, J. 2006. Can we identify sources of fine particles responsible for exercise-induced ischemia on days with elevated air pollution? The ULTRA study. Environ. Health Perspect. 114:655-660.
36. Matthias-Maser, S. 1998. Primary biological aerosol particles: Their significance, sources, sampling methods and size distribution in the atmosphere. In Atmospheric particles, eds. R. M. Harrison and R. E. van Grieken, pp. 349-368. Chichester, UK: John Wiley & Sons Ltd.
37. Metzger, K. M., Tolbert, P. E., Klein, M., Peel, J. L., Flanders, W. D., Todd, K., Mulholland, J. A., Ryan, P. B., and Frumkin, H. 2004. Ambient air pollution and cardiovascular emergency department visits. Epidemiology 15:46-56.
38. Naeher, L. P., Brauer, M., Lipsett, M., Zelikoff, J. T., Simpson, C. D., Koenig, J. Q., and Smith, K. R. 2007. Woodsmoke health effects: A review. Inhal. Toxicol. 19:67-106.
39. Pakkanen, T. A., Loukkola, K., Korhonen, C. H., Aurela, M., Mäkelä, T., Hillamo, R. E., Aarnio, P., Koskentalo, T., Kousa, A., and Maenhaut, W. 2001. Sources and chemical composition of atmospheric fine and coarse particles in the Helsinki area. Atmos. Environ. 35:5381-5391.
40. Pennanen, A. S., Sillanpää, M., Hillamo, R., Quass, U., John, A. C., Branis, M., Hnová, I., Meliefste, K., Janssen, N. A. H., Koskentalo, T., Castaño-Vinyals, G., Bouso, L., Chalbot, M.-C., Kavouras, I. G., and Salonen, R. O. 2007. Performance of a high-volume cascade impactor in six European urban environments: Mass measurement and chemical characterization of size-segregated particulate samples. Sci. Total Environ. 374:297-310.
41. Penttinen, P., Vallius, M., Tiittanen, P., Ruuskanen, J., and Pekkanen, J. 2006. Source-specific fine particles in urban air and respiratory function among adult asthmatics. Inhal. Toxicol. 18:191-198.
42. Prieditis, H., and Adamson, I. Y. R. 2002. Comparative pulmonary toxicity of various soluble metals found in urban particulate dusts. Exp. Lung Res. 28:563-576.
43. Pope, C. A., and Dockery, D. W. 2006. Health effects of fine particulate air pollution: Lines that connect. J. Air Waste Manage. Assoc. 56:709-742.
44. Rice, T. M., Clarke, R. W., Godleski, J. J., Al-Mutairi, E., Jiang, N.-F., Hauser, R., and Paulauskis, J. D. 2001. Differential ability of transition metals to induce pulmonary inflammation. Toxicol. Appl. Pharmacol. 177:46-53.
45. Saarnio, K., Sillanpää, M., Hillamo, R., Sandell, E., Pennanen, A. S., and Salonen, R. O. 2008. Polycyclic aromatic hydrocarbons in size-segregated particulate matter from six urban sites in Europe. Submitted.
46. Salonen R. O., Hälinen, A. I., Pennanen, A. S., Hirvonen, M.-R., Sillanpää, M., Hillamo, R., Shi, T., Borm, P., Sandell, E., Koskentalo, T., and Aarnio, P. 2004. Chemical and in vitro toxicologic characterization of wintertime and springtime urban-air particles with an aerodynamic diameter below 10 μm in Helsinki. Scand. J. Work Environ. Health 2:80-90.
47. Sandell, E., Kiviranta, A., Tuominen, J., and Aarnio, P. 1999. Concentration levels of polycyclic aromatic hydrocarbons (PAHs) in ambient air in Finland. Fresenius Environ. Bull. 8:567-575.
48. Schlesinger, R. B., and Cassee F. 2003. Atmospheric secondary inorganic particulate matter: the toxicological perspective as a basis for health effects risk assessment. Inhal. Toxicol. 15:197-235.
49. Schwarze, P. E., Øvrevik, J., Låg, M., Refsnes, M., Nafstad, P., Hetland, R. B., and Dybing, E. 2006. Particulate matter properties and health effects: consistency of epidemiological and toxicological studies. Hum. Exp. Toxicol. 25:559-579.
50. Seagrave, J. C., McDonald, J. D., Bedrick, E., Edgerton, E. S., Gigliotti, A. P., Jansen, J. J., Ke, L., Naeher, L. P., Seilkop, S. K., Zheng, M., and Mauderly J. L. 2006. Lung toxicity of ambient particulate matter from southeastern U.S. sites with different contributing sources: relationships between composition and effects. Environ. Health Perspect. 114:1387-1393.
51. Seinfeld J. H., and Pandis, S. N. 1998. Atmospheric chemistry and physics: From air pollution to climate change. New York: John Wiley and Sons.
52. Sillanpää, M., Hillamo, R., Mäkelä, T., Pennanen, A. S., and Salonen, R. O. 2003. Field and laboratory tests of a high volume cascade impactor. J. Aerosol. Sci. 34:485-500.
53. 10 mass concentrations of benzo[a]pyrene and carcinogenic heavy metals during contrasting air pollution situations in Europe (PAMCHAR). J. Aerosol. Sci. 35(suppl. 1):461-462 (abstr.).
54. Sillanpää, M., Frey, A., Hillamo, R., Pennanen, A. S., and Salonen, R. O. 2005 Organic, elemental and inorganic carbon in particulate matter of six urban environments in Europe. Atmos. Chem. Phys. 5:2869-2879.
55. Sillanpää, M., Hillamo, R., Saarikoski, S., Frey, A., Pennanen, A., Makkonen, U., Spolnik, Z., Van Grieken, R., Braniš, M., Brunekreef, B., Chalbot, M.-C., Kuhlbusch, T., Sunyer, J., Kerminen, V.-M., Kulmala, M., and Salonen, R. O. 2006. Chemical composition and mass closure of particulate matter at six urban sites in Europe. Atmos. Environ. 40S2:212-223.
56. Solhaug, A., Refsnes, M., Låg, M., Schwarze, P. E., Husøy, T., and Holme, J. A. 2004. Polycyclic aromatic hydrocarbons induce both apoptotic and anti-apoptotic signals in Hepa1c1c7 cells. Carcinogenesis 25:809-819.
57. Squadrito, G. L., Cueto, R., Dellinger, B., and Pryor, W. A. 2001. Quinoid redox cycling as a mechanism for sustained free radical generation by inhaled airborne matter. Free Radical Biol. Med. 31:1132-1138.
58. Steerenberg, P. A., van Amelsvoort, L., Lovik, M., Hetland, R. B., Alberg, T., Halatek, T., Bloemen, H. J. T., Rydzynski, K., Swaen, G., Schwarze, P., Dybing, E., and Cassee, F. R. 2006 Relation between sources of particulate air pollution and biological effect parameters in samples from four European cities: An exploratory study. Inhal. Toxicol. 18:333-346.
59. Teinilä, K., Kerminen, V.-M., and Hillamo, R. 2000. A study of size-segregated aerosol chemistry in the Antarctic atmosphere. J. Geophys. Res. 105:3893-3904.
60. U.S. Environmental Protection Agency. 2004. Air quality criteria for particulate matter. Publication EPA/600/P-99/002aF. Research Triangle Park, NC: U.S. EPA Office of Research and Development, National Center for Environmental Assessment-RTP Office.
61. World Health Organization. 2003. Review of health aspects of air pollution with particulate matter, ozone and nitrogen dioxide. Report EUR/03/5042688 of working group, Bonn, Germany, 13-15 January. Copenhagen, Denmark: WHO Regional Office for Europe.
62. World Health Organization, International Program of Chemical Safety. 1998. Selected non-heterocyclic polycyclic aromatic hydrocarbons. Environmental Health Criteria 202. Geneva, Switzerland.
63. x, and CO from on-road vehicles in Finland. Atmos. Environ. 39:6696-6706.