Apoptosis and bax expression are increased by coal dust in the polycyclic aromatic hydrocarbon-exposed lung

Environmental Health Perspectives

Volumn 114, Issue 9, 2006, Pages 1367-1373

  Ghanem, Mohamed M ^a,b   Battelli, Lori A ^a,b   Mercer, Robert R ^b   Scabilloni, James F ^b   Kashon, Michael L ^b   Ma, Jane Y C ^b   Nath, Joginder ^a   Hubbs, Ann F ^b  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b NATIONAL INSTITUTE FOR OCCUPATIONAL SAFETY AND HEALTH   (United States)

Author keywords

Apoptosis; Bax; Caspase; Coal dust; CYP1A1; CYP2B1; Modifiers; Pneumoconiosis; Polycyclic aromatic hydrocarbons; Xenobiotic metabolism

Indexed keywords

BETA NAPHTHOFLAVONE; CASPASE; CASPASE INHIBITOR; CIGARETTE SMOKE; COAL; CYTOCHROME P450 1A1; CYTOCHROME P450 2B1; CYTOKERATIN 18; CYTOKERATIN 8; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN BAX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL HYPERPLASIA; CELL SWELLING; COAL WORKER; CONTROLLED STUDY; DIESEL ENGINE; DIGITAL IMAGING; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; IMMUNOFLUORESCENCE; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG INJURY; LUNG TOXICITY; MALE; NONHUMAN; OCCUPATIONAL DISEASE; OCCUPATIONAL EXPOSURE; PNEUMOCONIOSIS; PNEUMONIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SILICOSIS; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; ARYL HYDROCARBON HYDROXYLASES; BETA-NAPHTHOFLAVONE; CASPASES; COAL; CYTOCHROME P-450 CYP1A1; DOSE-RESPONSE RELATIONSHIP, DRUG; DUST; GENE EXPRESSION REGULATION; LUNG; MALE; PNEUMONIA; POLYCYCLIC HYDROCARBONS, AROMATIC; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33748139421     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.8906     Document Type: Article

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