Acute pulmonary toxicity of particulate matter filter extracts in rats: Coherence with epidemiologic studies in Utah valley residents

Environmental Health Perspectives

Volumn 109, Issue SUPPL. 3, 2001, Pages 395-403

  Dye, J A ^a   Lehmann, J R ^a   McGee, J K ^a   Winsett, D W ^a   Ledbetter, A D ^a   Everitt, J I ^a   Ghio, A J ^a   Costa, D L ^a  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Filter extraction; Lung inflammation; Lung injury; Metals; Particulate matter (PM); Pulmonary toxicity; Rats; Steel mill; Total suspended particulates (TSP); Utah Valley

Indexed keywords

ACETYLCHOLINE; ARSENIC; CALCIUM ION; CATION; COPPER; GLASS; IRON; LEAD; MAGNESIUM ION; MANGANESE; METAL; NICKEL; POTASSIUM ION; SODIUM; SODIUM CHLORIDE; STEEL; STRONTIUM; SULFATE; ZINC;

AIR POLLUTION; AMBIENT AIR; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISEASE ASSOCIATION; EPIDEMIOLOGY; EXPOSURE; EXTRACT; FILTER; HEALTH HAZARD; HISTOPATHOLOGY; HOSPITAL ADMISSION; HUMAN; INDUSTRY; INFLAMMATION; LEUKOCYTE COUNT; LUNG INJURY; LUNG LAVAGE; LYMPHOCYTE COUNT; MALE; MASS SPECTROMETRY; NEUTROPHIL; NONHUMAN; PARTICULATE MATTER; PRIORITY JOURNAL; RAT; RESIDENT; RESPIRATORY TRACT DISEASE; SUSPENDED PARTICULATE MATTER; TOXICITY; UNITED STATES; WINTER;

EID: 0034954537     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.01109s3395     Document Type: Article

References (30)

1. Health effects of outdoor air pollution
2. Review of epidemiological evidence of health effects of particulate air pollution
3. Respiratory disease associated with community air pollution and a steel mill, Utah Valley
4. Characterization of upper respiratory disease in rats following neonatal inoculation with rat-adapted influenza virus
5. Statistics for toxicologists
6. Role of particle-associated endotoxin in ambient air particulate matter-induced pulmonary inflammation
7. Bioavailable transition metals in particulate matter mediate cardiopulmonary injury in health and compromised animal models
8. Acute respiratory effects of particulate air pollution
9. 10 pollution in Utah, Salt Lake, and Cache Valleys
10. 10 pollution on symptomatic and asymptomatic children
11. 10 pollution in Utah Valley
12. 10 pollution in Utah Valley
13. Particulate pollution and health: A review of the Utah Valley experience
14. Inflammatory lung injury after instillation of humans with air pollution particles
15. Soluble components of Utah Valley particulate pollution alter alveolar macrophage function in vivo and in vitro
16. 10 filters from the Utah Valley on human airway epithelial cells
17. Heavy metal sorption of clay minerals affected by the siderophore desferrioxamine B
18. Lipopolysaccharide priming amplifies lung macrophage tumor necrosis factor production in response to air particles
19. Alveolar macrophage cytokine production in response to air particles in vitro: Role of endotoxin
20. Pulmonary deposition, clearance and effects of inhaled soluble and insoluble cadmium compounds
21. Soluble transition metals mediate residual oil fly ash induced acute lung injury
22. Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals
23. Both inhaled histamine and hypertonic saline increase airway reactivity in non-sensitised rabbits
24. Hypertonic saline increases vascular permeability in the rat trachea by producing neurogenic inflammation
25. Models and mechanisms of exercise-induced asthma
26. Inhalant corticosteroids inhibit hyperosmolarity-induced, and cooling and rewarming-induced interleukin-8 and RANTES production by human bronchial epithelial cells
27. Relative toxicity of particulate matter (PM)-associated metals on airway epithelial injury and chemokine production
28. Airway epithelial cell responses to metal constituents of particulate matter (PM) and the potential for metal interactions