Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway

FEBS Journal

Volumn 275, Issue 23, 2008, Pages 5947-5959

  Vargas, Patrick D ^a   Furuyama, Kazumichi ^a   Sassa, Shigeru ^b   Shibahara, Shigeki ^a  

^a TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Erythroid cells; Heme; Hepatocyte; Hypoxia inducible factor 1; Porphyria

Indexed keywords

COBALT CHLORIDE; DEFEROXAMINE; HEME; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; PORPHOBILINOGEN DEAMINASE; TETRAPYRROLE DERIVATIVE; UROPORPHYRINOGEN III SYNTHASE;

ARTICLE; CONTROLLED STUDY; ERYTHROID CELL; FEMALE; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPOXIA; LIVER CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA STABILITY;

BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL HYPOXIA; CELL LINE, TUMOR; COBALT; DEFEROXAMINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEME; HUMANS; HYDROXYMETHYLBILANE SYNTHASE; ISOENZYMES; JURKAT CELLS; K562 CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA STABILITY; RNA, MESSENGER; TETRAPYRROLES; UROPORPHYRINOGEN III SYNTHETASE;

EID: 55949086855     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2008.06723.x     Document Type: Article

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