The transcriptome of Plasmodium vivax reveals divergence and diversity of transcriptional regulation in malaria parasites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 42, 2008, Pages 16290-16295

  Bozdech, Zbynek ^a   Mok, Sachel ^a   Hu, Guangan ^a   Imwong, Mallika ^b   Jaidee, Anchalee ^c   Russell, Bruce ^d   Ginsburg, Hagai ^e   Nosten, Francois ^c   Day, Nicholas P J ^b   White, Nicholas J ^b   Carlton, Jane M ^f   Preiser, Peter R ^a,g  

^a NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^b MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

^d AGENCY FOR SCIENCE   (Singapore)

^e HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^f NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^g NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Comparative genomics; Plasmodium falciparum

Indexed keywords

PROTOZOAL PROTEIN; TRANSCRIPTOME;

ADULT; ARTICLE; CELL FUNCTION; GENE EXPRESSION; HOST PATHOGEN INTERACTION; HUMAN; MALARIA; MICROBIAL DIVERSITY; NONHUMAN; PARASITE ISOLATION; PARASITE VIRULENCE; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PREDICTION; PRIORITY JOURNAL; SPECIES DIFFERENCE; TRANSCRIPTION REGULATION;

ANIMALS; CHROMOSOMES; ERYTHROCYTES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; MALARIA; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; REGULATORY ELEMENTS, TRANSCRIPTIONAL; TRANSCRIPTION, GENETIC;

PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX;

EID: 55849142984     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0807404105     Document Type: Article

References (47)

1. Mendis K, Sina BJ, Marchesini P, Carter R (2001) The neglected burden of Plasmodium vivax malaria. Am J Trop Med Hyg 64:97-106.
2. Price RN, et al. (2007) Vivax malaria: Neglected and not benign. Am J Trop Med Hyg 77:79-87.
3. Hay SI, et al. (2004) The global distribution and population at risk of malaria: Past, present, and future. Lancet Infect Dis 4:327-336.
4. Krotoski WA, et al. (1986) Observations on early and late post-sporozoite tissue stages in primate malaria. IV. Pre-erythrocytic schizonts and/or hypnozoites of Chesson and North Korean strains of Plasmodium vivax in the chimpanzee. Am J Trop Med Hyg 35:263-274.
5. Gardner MJ, et al. (2002) Genome sequence of the human malaria parasite Plasmodium falciparum. Nature 419:498-511.
6. Bozdech Z, et al. (2003) The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS Biol 1:E5.
7. Le Roch KG, et al. (2003) Discovery of gene function by expression profiling of the malaria parasite life cycle. Science 301:1503-1508.
8. Grannham PCC (1966) Malaria Parasites and Haemosporidia (Blackwell Scientific Publications, Oxford).
9. Mons B (1990) Preferential invasion of malarial merozoites into young red blood cells. Blood Cells 16:299-312.
10. Aikawa M (1971) Parasitological review. Plasmodium: The fine structure of malarial parasites. Exp Parasitol 30:284-320.
11. Aikawa M, Miller LH, Rabbege J (1975) Caveola-vesicle complexes in the plasmalemma of erythrocytes infected by Plasmodium vivax and P cynomolgi. Unique structures related to Schuffner's dots. Am J Pathol 79:285-300.
12. Suwanarusk R, et al. (2004) The deformability of red blood cells parasitized by Plasmodium falciparum and P. vivax. J Infect Dis 189:190-194.
13. Carlton J, et al. (2008) Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature, in press.
14. Russell BM, et al. (2003) Simple in vitro assay for determining the sensitivity of Plasmodium vivax isolates from fresh human blood to antimalarials in areas where P. vivax is endemic. Antimicrob Agents Chemother 47:170-173.
15. Hu G, et al. (2007) Selection of long oligonucleotides for gene expression microarrays using weighted rank-sum strategy. BMC Bioinformatics 8:350-362.
16. del Portillo HA, et al. (2001) A superfamily of variant genes encoded in the subtelomeric region of Plasmodium vivax. Nature 410:839-842.
17. Jalah R, et al. (2005) Identification, expression, localization and serological characterization of a tryptophan-rich antigen from the human malaria parasite Plasmodium vivax. Mol Biochem Parasitol 142:158-169.
18. Duraisingh MT, et al. (2005) Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum. Cell 121:13-24.
19. Freitas-Junior LH, et al. (2005) Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites. Cell 121:25-36.
20. Tham WH, Payne PD, Brown GV, Rogerson SJ (2007) Identification of basic transcriptional elements required for rif gene transcription. Int J Parasitol 37:605-615.
21. Galinski MR, Medina CC, Ingravallo P, Barnwell JW (1992) A reticulocyte-binding protein complex of Plasmodium vivax merozoites. Cell 69:1213-1226.
22. Drew DR, Sanders PR, Crabb BS (2005) Plasmodium falciparum merozoite surface protein 8 is a ring-stage membrane protein that localizes to the parasitophorous vacuole of infected erythrocytes. Infect Immun 73:3912-3922.
23. Rug M, et al. (2006) The role of KAHRP domains in knob formation and cytoadherence of P falciparum-infected human erythrocytes. Blood 108:370-378.
24. Ginsburg H (2006) Progress in in silico functional genomics: The malaria Metabolic Pathways database. Trends Parasitol 22:238-240.
25. Saliba KJ, et al. (2003) Acidification of the malaria parasite's digestive vacuole by a H+-ATPase and a H+-pyrophosphatase. J Biol Chem 278:5605-5612.
26. Martin RE, et al. (2005) The "permeome" of the malaria parasite: An overview of the membrane transport proteins of Plasmodium falciparum. Genome Biol 6:R26.
27. Sharrock WW, et al. (2008) Plasmodium vivax trophozoites insensitive to chloroquine. Malar J 7:94-100.
28. Spielmann T, et al. (2006) Organization of ETRAMPs and EXP-1 at the parasite-host cell interface of malaria parasites. Mol Microbiol 59:779-794.
29. Mills JP, et al. (2007) Effect of plasmodial RESA protein on deformability of human red blood cells harboring Plasmodium falciparum. Proc Natl Acad Sci USA 104:9213-9217.
30. Culvenor JG, Day KP, Anders RF (1991) Plasmodium falciparum ring-infected erythrocyte surface antigen is released from merozoite dense granules after erythrocyte invasion. Infect Immun 59:1183-1187.
31. Ward P, Equinet L, Packer J, Doerig C (2004) Protein kinases of the human malaria parasite Plasmodium falciparum: The kinome of a divergent eukaryote. BMC Genomics 5:79-97.
32. Dorin D, et al. (2005) PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical three-component MAPK pathways in the human malaria parasite Plasmodium falciparum. Mol Microbiol 55:184-196.
33. Osmani SA, Pu RT, Morris NR (1988) Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase. Cell 53:237-244.
34. Balaji S, Babu MM, Iyer LM, Aravind L (2005) Discovery of the principal specific transcription factors of Apicomplexa and their implication for the evolution of the AP2-integrase DNA binding domains. Nucleic Acids Res 33:3994-4006.
35. De Silva EK, et al. (2008) Specific DNA-binding by apicomplexan AP2 transcription factors. Proc Natl Acad Sci USA 105:8393-8398.
36. Tjitra E, et al. (2008) Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: A prospective study in Papua, Indonesia. PLoS Med 5:e128.
37. Karunaweera ND, et al. (2008) Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene 410:105-112.
38. Suwanarusk R, et al. (2007) Chloroquine resistant Plasmodium vivax: In vitro characterisation and association with molecular polymorphisms. PLoS ONE 2:e1089.
39. Fernandez-Becerra C, et al. (2005) Variant proteins of Plasmodium vivax are not clonally expressed in natural infections. Mol Microbiol 58:648-658.
40. Sargeant TJ, et al. (2006) Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites. Genome Biol 7:R12.
41. Cortes A, et al. (2007) Epigenetic silencing of Plasmodium falciparum genes linked to erythrocyte invasion. PLoS Pathog 3:e107.
42. Iyer JK, Amaladoss A, Genesan S, Preiser PR (2007) Variable expression of the 235-kDa rhoptry protein of Plasmodium yoelii mediate host cell adaptation and immune evasion. Mol Microbiol 65:333-346.
43. Nery S, et al. (2006) Expression of Plasmodium falciparum genes involved in erythrocyte invasion varies among isolates cultured directly from patients. Mol Biochem Parasitol 149:208-215.
44. Gaur D, Mayer DC, Miller LH (2004) Parasite ligand-host receptor interactions during invasion of erythrocytes by Plasmodium merozoites. Int J Parasitol 34:1413-1429.
45. Daily JP, et al. (2007) Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature 450:1091-1095.
46. Llinas M, et al. (2006) Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains. Nucleic Acids Res 34:1166-1173.
47. Gunasekera AM, et al. (2007) Plasmodium falciparum: Genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment. Exp Parasitol 117:87-92.