메뉴 건너뛰기




Volumn 29, Issue 9, 2008, Pages 445-453

Serotonin research: Contributions to understanding psychoses

Author keywords

[No Author keywords available]

Indexed keywords

PSYCHEDELIC AGENT; SEROTONIN; SEROTONIN AGONIST;

EID: 55849099288     PISSN: 01656147     EISSN: 18733735     Source Type: Journal    
DOI: 10.1016/j.tips.2008.06.006     Document Type: Review
Times cited : (339)

References (60)
  • 1
    • 0001688086 scopus 로고
    • Lysergsäure-diäthylamid, ein Phantastikum aus der Mutterkorngruppe
    • Stoll, W.A. (1947) Lysergsäure-diäthylamid, ein Phantastikum aus der Mutterkorngruppe. Schweiz. Arch. Neurol. Psychiat 60, 279-323
    • (1947) Schweiz. Arch. Neurol. Psychiat , vol.60 , pp. 279-323
    • Stoll, W.A.1
  • 2
    • 1642273671 scopus 로고    scopus 로고
    • Acute psychological and physiological effects of psilocybin in healthy humans: A double-blind, placebo-controlled dose-effect study
    • Hasler, F. et al. (2004) Acute psychological and physiological effects of psilocybin in healthy humans: a double-blind, placebo-controlled dose-effect study. Psychopharmacology (Berl.) 172, 145-156
    • (2004) Psychopharmacology (Berl.) , vol.172 , pp. 145-156
    • Hasler, F.1
  • 3
    • 0005715910 scopus 로고
    • Mescaline, lysergic acid diethylamid and psilocybin: Comparison of clinical syndromes, effects on color perception and biochemical measures
    • Hollister, L.E. and Hartmann, A.M. (1962) Mescaline, lysergic acid diethylamid and psilocybin: comparison of clinical syndromes, effects on color perception and biochemical measures. Comparative Psychiatry 3, 235-241
    • (1962) Comparative Psychiatry , vol.3 , pp. 235-241
    • Hollister, L.E.1    Hartmann, A.M.2
  • 4
    • 0031824265 scopus 로고    scopus 로고
    • The standardized psychometric assessment of altered states of consciousness (ASCs) in humans
    • Dittrich, A. (1998) The standardized psychometric assessment of altered states of consciousness (ASCs) in humans. Pharmacopsychiatry 31, 80-84
    • (1998) Pharmacopsychiatry , vol.31 , pp. 80-84
    • Dittrich, A.1
  • 5
    • 0015241565 scopus 로고
    • A cartography of the ecstatic and meditative states
    • Fischer, R. (1971) A cartography of the ecstatic and meditative states. Science 174, 897-904
    • (1971) Science , vol.174 , pp. 897-904
    • Fischer, R.1
  • 8
    • 0013952056 scopus 로고
    • "Psychedelic" experiences in acute psychoses
    • Bowers, M.B. and Freedman, D.X. (1966) "Psychedelic" experiences in acute psychoses. Arch. Gen. Psychiatry 15, 240-248
    • (1966) Arch. Gen. Psychiatry , vol.15 , pp. 240-248
    • Bowers, M.B.1    Freedman, D.X.2
  • 9
    • 0013890775 scopus 로고
    • The early symptoms of schizophrenia
    • Chapman, J. (1966) The early symptoms of schizophrenia. Br. J. Psychiatry 112, 225-251
    • (1966) Br. J. Psychiatry , vol.112 , pp. 225-251
    • Chapman, J.1
  • 10
    • 0031856738 scopus 로고    scopus 로고
    • History, rationale and potential of human experimental hallucinogen drug research in psychiatry
    • Gouzoulis-Mayfrank, E. et al. (1998) History, rationale and potential of human experimental hallucinogen drug research in psychiatry. Pharmacopsychiatry 31, 63-68
    • (1998) Pharmacopsychiatry , vol.31 , pp. 63-68
    • Gouzoulis-Mayfrank, E.1
  • 11
    • 0032230203 scopus 로고    scopus 로고
    • Hallucinogenic drug induced states resemble acute endogenous psychoses: Results of an empirical study
    • Gouzoulis-Mayfrank, E. et al. (1998) Hallucinogenic drug induced states resemble acute endogenous psychoses: results of an empirical study. Eur. Psychiatry 13, 399-406
    • (1998) Eur. Psychiatry , vol.13 , pp. 399-406
    • Gouzoulis-Mayfrank, E.1
  • 12
    • 0013826050 scopus 로고
    • Similarity of schizophrenia and the psilocybin syndrome as determined by objective methods
    • Keeler, M.H. (1965) Similarity of schizophrenia and the psilocybin syndrome as determined by objective methods. Int. J. Neuropsychiatry 1, 630-634
    • (1965) Int. J. Neuropsychiatry , vol.1 , pp. 630-634
    • Keeler, M.H.1
  • 13
    • 0031854766 scopus 로고    scopus 로고
    • Blood flow and cerebral laterality in the mescaline model of psychosis
    • Hermle, L. et al. (1998) Blood flow and cerebral laterality in the mescaline model of psychosis. Pharmacopsychiatry 31 (Suppl. 2), 85-91
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. 2 , pp. 85-91
    • Hermle, L.1
  • 14
    • 0842277272 scopus 로고    scopus 로고
    • Brain mechanisms of hallucinogens and entactogens
    • Vollenweider, F.X. (2001) Brain mechanisms of hallucinogens and entactogens. Dialogues Clin. Neurosci. 3, 265-279
    • (2001) Dialogues Clin. Neurosci. , vol.3 , pp. 265-279
    • Vollenweider, F.X.1
  • 15
    • 0842324481 scopus 로고    scopus 로고
    • Hallucinogens
    • Nichols, D.E. (2004) Hallucinogens. Pharmacol. Ther. 101, 131-181
    • (2004) Pharmacol. Ther. , vol.101 , pp. 131-181
    • Nichols, D.E.1
  • 16
    • 0015899847 scopus 로고
    • Early subjective experiences in schizophrenic episodes
    • Freedman, B. and Chapman, L.J. (1973) Early subjective experiences in schizophrenic episodes. J. Abnorm. Psychol. 82, 46-54
    • (1973) J. Abnorm. Psychol. , vol.82 , pp. 46-54
    • Freedman, B.1    Chapman, L.J.2
  • 17
    • 0015318561 scopus 로고
    • Symptom differences in schizophrenia with good and poor prognosis
    • McCabe, M.S. et al. (1972) Symptom differences in schizophrenia with good and poor prognosis. Am. J. Psychiatry 128, 1239-1243
    • (1972) Am. J. Psychiatry , vol.128 , pp. 1239-1243
    • McCabe, M.S.1
  • 18
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • Braff, D.L. et al. (2001) Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl.) 156, 234-258
    • (2001) Psychopharmacology (Berl.) , vol.156 , pp. 234-258
    • Braff, D.L.1
  • 19
    • 0023600009 scopus 로고
    • Startle habituation and sensorimotor gating in schizophrenia and related animal models
    • Geyer, M.A. and Braff, D.L. (1987) Startle habituation and sensorimotor gating in schizophrenia and related animal models. Schizophr. Bull. 13, 643-668
    • (1987) Schizophr. Bull. , vol.13 , pp. 643-668
    • Geyer, M.A.1    Braff, D.L.2
  • 20
    • 0013578406 scopus 로고
    • Disorders of attention and perception in early schizophrenia
    • McGhie, A. and Chapman, J. (1961) Disorders of attention and perception in early schizophrenia. Br. J. Med. Psychol. 34, 103-116
    • (1961) Br. J. Med. Psychol. , vol.34 , pp. 103-116
    • McGhie, A.1    Chapman, J.2
  • 21
    • 0031855523 scopus 로고    scopus 로고
    • Advances and pathophysiological models of hallucinogen drug actions in humans: A preamble to schizophrenia research
    • Vollenweider, F.X. (1998) Advances and pathophysiological models of hallucinogen drug actions in humans: a preamble to schizophrenia research. Pharmacopsychiatry 31, 92-103
    • (1998) Pharmacopsychiatry , vol.31 , pp. 92-103
    • Vollenweider, F.X.1
  • 22
    • 0035891880 scopus 로고    scopus 로고
    • A systems model of altered consciousness: Integrating natural and drug-induced psychoses
    • Vollenweider, F.X. and Geyer, M.A. (2001) A systems model of altered consciousness: integrating natural and drug-induced psychoses. Brain Res. Bull. 56, 495-507
    • (2001) Brain Res. Bull. , vol.56 , pp. 495-507
    • Vollenweider, F.X.1    Geyer, M.A.2
  • 23
    • 0037770351 scopus 로고    scopus 로고
    • Deficits in prepulse inhibition and habituation in never-medicated first-episode schizophrenia
    • Ludewig, K. et al. (2003) Deficits in prepulse inhibition and habituation in never-medicated first-episode schizophrenia. Biol. Psychiatry 54, 121-128
    • (2003) Biol. Psychiatry , vol.54 , pp. 121-128
    • Ludewig, K.1
  • 24
    • 2942599183 scopus 로고    scopus 로고
    • Animal models relevant to schizophrenia disorders
    • (Davis, K.L. et al., eds), Lippincott Williams & Wilkins
    • Geyer, M.A. and Moghaddam, B. (2002) Animal models relevant to schizophrenia disorders. In Neuropsychopharmacology: The Fifth Generation of Progress (Davis, K.L. et al., eds), pp. 689-701, Lippincott Williams & Wilkins
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 689-701
    • Geyer, M.A.1    Moghaddam, B.2
  • 25
    • 0031824264 scopus 로고    scopus 로고
    • Behavioral studies of hallucinogenic drugs in animals: Implications for schizophrenia research
    • Geyer, M.A. (1998) Behavioral studies of hallucinogenic drugs in animals: implications for schizophrenia research. Pharmacopsychiatry 31 (Suppl. 2), 73-79
    • (1998) Pharmacopsychiatry , vol.31 , Issue.SUPPL. 2 , pp. 73-79
    • Geyer, M.A.1
  • 26
    • 34547882413 scopus 로고    scopus 로고
    • 2A agonist psilocybin on prepulse inhibition of startle in healthy human volunteers depend on interstimulus interval
    • 2A agonist psilocybin on prepulse inhibition of startle in healthy human volunteers depend on interstimulus interval. Neuropsychopharmacology 32, 1876-1887
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1876-1887
    • Vollenweider, F.X.1
  • 27
    • 36448990087 scopus 로고    scopus 로고
    • Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans
    • Carter, O.L. et al. (2007) Psilocybin links binocular rivalry switch rate to attention and subjective arousal levels in humans. Psychopharmacology (Berl.) 195, 415-424
    • (2007) Psychopharmacology (Berl.) , vol.195 , pp. 415-424
    • Carter, O.L.1
  • 28
    • 0032430801 scopus 로고    scopus 로고
    • Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action
    • Vollenweider, F.X. et al. (1998) Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action. Neuroreport 9, 3897-3902
    • (1998) Neuroreport , vol.9 , pp. 3897-3902
    • Vollenweider, F.X.1
  • 29
    • 36349009767 scopus 로고    scopus 로고
    • 2A receptor density is decreased in the at-risk mental state
    • 2A receptor density is decreased in the at-risk mental state. Psychopharmacology (Berl.) 195, 579-590
    • (2008) Psychopharmacology (Berl.) , vol.195 , pp. 579-590
    • Hurlemann, R.1
  • 31
    • 0032401137 scopus 로고    scopus 로고
    • Serotonergic basis of antipsychotic drug effects in schizophrenia
    • Lieberman, J.A. et al. (1998) Serotonergic basis of antipsychotic drug effects in schizophrenia. Biol. Psychiatry 44, 1099-1117
    • (1998) Biol. Psychiatry , vol.44 , pp. 1099-1117
    • Lieberman, J.A.1
  • 32
    • 0032868798 scopus 로고    scopus 로고
    • The role of serotonin in antipsychotic drug action
    • Meltzer, H.Y. (1999) The role of serotonin in antipsychotic drug action. Neuropsychopharmacology 21, 106S-115S
    • (1999) Neuropsychopharmacology , vol.21
    • Meltzer, H.Y.1
  • 33
    • 0033763169 scopus 로고    scopus 로고
    • Immediate effects of risperidone on corticostriato-thalamic loops and the hippocampus
    • Liddle, P.F. et al. (2000) Immediate effects of risperidone on corticostriato-thalamic loops and the hippocampus. Br. J. Psychiatry 177, 402-407
    • (2000) Br. J. Psychiatry , vol.177 , pp. 402-407
    • Liddle, P.F.1
  • 34
    • 32844461728 scopus 로고    scopus 로고
    • Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia
    • Lahti, A.C. et al. (2006) Correlations between rCBF and symptoms in two independent cohorts of drug-free patients with schizophrenia. Neuropsychopharmacology 31, 221-230
    • (2006) Neuropsychopharmacology , vol.31 , pp. 221-230
    • Lahti, A.C.1
  • 35
    • 0030917261 scopus 로고    scopus 로고
    • Correlation of positive symptoms exclusively to hyperperfusion or hypoperfusion of cerebral cortex in never-treated schizophrenics
    • Sabri, O. et al. (1997) Correlation of positive symptoms exclusively to hyperperfusion or hypoperfusion of cerebral cortex in never-treated schizophrenics. Lancet 349, 1735-1739
    • (1997) Lancet , vol.349 , pp. 1735-1739
    • Sabri, O.1
  • 36
    • 0028943849 scopus 로고
    • Ketamine activates psychosis and alters limbic blood flow in schizophrenia
    • Lahti, A.C. et al. (1995) Ketamine activates psychosis and alters limbic blood flow in schizophrenia. Neuroreport 6, 869-872
    • (1995) Neuroreport , vol.6 , pp. 869-872
    • Lahti, A.C.1
  • 37
    • 48949094239 scopus 로고    scopus 로고
    • 2A receptor polymorphisms
    • 2A receptor polymorphisms. Biol. Psychiatry 64, 434-437 (www.sciencedirect.com)
    • (2008) Biol. Psychiatry , vol.64 , pp. 434-437
    • Quednow, B.B.1
  • 38
    • 34447581237 scopus 로고    scopus 로고
    • Association of a serotonin receptor 2A gene polymorphism with cognitive functions in patients with schizophrenia
    • Üçok, A. et al. (2007) Association of a serotonin receptor 2A gene polymorphism with cognitive functions in patients with schizophrenia. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 144B, 704-707
    • (2007) Am. J. Med. Genet. B. Neuropsychiatr. Genet. , vol.144 B , pp. 704-707
    • Üçok, A.1
  • 39
    • 84951655689 scopus 로고
    • Some neurophysiological aspects of serotonin
    • Woolley, D.W. and Shaw, E. (1954) Some neurophysiological aspects of serotonin. BMJ 2, 122-126
    • (1954) BMJ , vol.2 , pp. 122-126
    • Woolley, D.W.1    Shaw, E.2
  • 40
    • 0001209293 scopus 로고
    • Some serotoninlike activities of lysergic acid diethylamide
    • Shaw, E. and Woolley, D.W. (1956) Some serotoninlike activities of lysergic acid diethylamide. Science 124, 121-122
    • (1956) Science , vol.124 , pp. 121-122
    • Shaw, E.1    Woolley, D.W.2
  • 41
    • 33751103938 scopus 로고    scopus 로고
    • 2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats
    • 2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl.) 189, 319-329
    • (2006) Psychopharmacology (Berl.) , vol.189 , pp. 319-329
    • Krebs-Thomson, K.1
  • 43
    • 0032803365 scopus 로고    scopus 로고
    • The effects of M100907 in pharmacological and developmental animal models of prepulse inhibition deficits in schizophrenia
    • Geyer, M.A. et al. (1999) The effects of M100907 in pharmacological and developmental animal models of prepulse inhibition deficits in schizophrenia. Neuropsychopharmacology 21, 134-142
    • (1999) Neuropsychopharmacology , vol.21 , pp. 134-142
    • Geyer, M.A.1
  • 44
    • 0034741106 scopus 로고    scopus 로고
    • 2A receptor inverse agonists as antipsychotics
    • 2A receptor inverse agonists as antipsychotics. J. Pharmacol. Exp. Ther. 299, 268-276
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 268-276
    • Weiner, D.M.1
  • 45
    • 0010411289 scopus 로고    scopus 로고
    • The role of preclinical models in the development of psychotropic drugs
    • (Davis, K.L. et al., eds), Lippincott Williams & Wilkins
    • Geyer, M.A. and Markou, A. (2002) The role of preclinical models in the development of psychotropic drugs. In Neuropsychopharmacology: The Fifth Generation of Progress (Davis, K.L. et al., eds), pp. 445-455, Lippincott Williams & Wilkins
    • (2002) Neuropsychopharmacology: The Fifth Generation of Progress , pp. 445-455
    • Geyer, M.A.1    Markou, A.2
  • 46
    • 34748864737 scopus 로고    scopus 로고
    • The pipeline and future of drug development in schizophrenia
    • Gray, J.A. and Roth, B.L. (2007) The pipeline and future of drug development in schizophrenia. Mol. Psychiatry 12, 904-922
    • (2007) Mol. Psychiatry , vol.12 , pp. 904-922
    • Gray, J.A.1    Roth, B.L.2
  • 47
    • 41649109395 scopus 로고    scopus 로고
    • 2C receptor agonists as an innovative approach for psychiatric disorders
    • 2C receptor agonists as an innovative approach for psychiatric disorders. Drug News Perspect. 20, 565-571
    • (2007) Drug News Perspect. , vol.20 , pp. 565-571
    • Rosenzweig-Lipson, S.1
  • 48
    • 0005134582 scopus 로고
    • The continuum of CNS excitatory states and hallucinosis
    • (Siegel, R.K. and West, L.J., eds), John Wiley and Sons
    • Winters, W.D. (1975) The continuum of CNS excitatory states and hallucinosis. In Hallucinations. Behavior, Experience and Theory (Siegel, R.K. and West, L.J., eds), pp. 53-70, John Wiley and Sons
    • (1975) Hallucinations. Behavior, Experience and Theory , pp. 53-70
    • Winters, W.D.1
  • 51
    • 33644827689 scopus 로고    scopus 로고
    • The neurochemical circuitry of schizophrenia
    • Carlsson, A. (2006) The neurochemical circuitry of schizophrenia. Pharmacopsychiatry 39 (Suppl. 1), S10-S14
    • (2006) Pharmacopsychiatry , vol.39 , Issue.SUPPL. 1
    • Carlsson, A.1
  • 52
    • 0030750579 scopus 로고    scopus 로고
    • 2A receptors in the ventral pallidum
    • 2A receptors in the ventral pallidum. Brain Res. 761, 97-104
    • (1997) Brain Res. , vol.761 , pp. 97-104
    • Sipes, T.E.1    Geyer, M.A.2
  • 53
    • 0038302714 scopus 로고    scopus 로고
    • Naturalizing consciousness: A theoretical framework
    • Edelman, G.M. (2003) Naturalizing consciousness: a theoretical framework. Proc. Natl. Acad. Sci. U. S. A. 100, 5520-5524
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 5520-5524
    • Edelman, G.M.1
  • 54
    • 33846549510 scopus 로고    scopus 로고
    • 2A receptor-mediated signaling pathways to affect behavior
    • 2A receptor-mediated signaling pathways to affect behavior. Neuron 53, 439-452
    • (2007) Neuron , vol.53 , pp. 439-452
    • González-Maeso, J.1
  • 55
    • 34547198448 scopus 로고    scopus 로고
    • A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis
    • Benneyworth, M.A. et al. (2007) A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Mol. Pharmacol. 72, 477-484
    • (2007) Mol. Pharmacol. , vol.72 , pp. 477-484
    • Benneyworth, M.A.1
  • 56
    • 40449139964 scopus 로고    scopus 로고
    • Identification of a serotonin/glutamate receptor complex implicated in psychosis
    • González-Maeso, J. et al. (2008) Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature 452, 93-97
    • (2008) Nature , vol.452 , pp. 93-97
    • González-Maeso, J.1
  • 57
    • 34948858402 scopus 로고    scopus 로고
    • Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
    • Patil, S.T. et al. (2007) Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat. Med. 13, 1102-1107
    • (2007) Nat. Med. , vol.13 , pp. 1102-1107
    • Patil, S.T.1
  • 58
    • 0003842954 scopus 로고
    • Serum vasoconstrictor, serotonin; chemical inactivation
    • Rapport, M.M. et al. (1948) Serum vasoconstrictor, serotonin; chemical inactivation. J. Biol. Chem. 176, 1237-1241
    • (1948) J. Biol. Chem. , vol.176 , pp. 1237-1241
    • Rapport, M.M.1
  • 59
    • 84959069373 scopus 로고
    • Drugs which antagonize 5-hydroxytryptamine
    • Gaddum, J.H. and Hammeed, K.A. (1954) Drugs which antagonize 5-hydroxytryptamine. Br. J. Pharmacol. 9, 240-248
    • (1954) Br. J. Pharmacol. , vol.9 , pp. 240-248
    • Gaddum, J.H.1    Hammeed, K.A.2
  • 60
    • 34250549693 scopus 로고
    • Elucidation of the structure and the synthesis of psilocybin
    • in German
    • Hofmann, A. et al. (1958) [Elucidation of the structure and the synthesis of psilocybin.] (in German). Experientia 14, 397-399
    • (1958) Experientia , vol.14 , pp. 397-399
    • Hofmann, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.