MRI detects therapeutic effects in weanling Niemann-Pick type C mice

Journal of Neuroscience Research

Volumn 86, Issue 12, 2008, Pages 2802-2807

  Lope Piedrafita, Silvia ^a,d   Totenhagen, John W ^a   Hicks, Chad M ^a   Erickson, Robert P ^b,c   Trouard, Theodore P ^a,a,c  

^a UNIVERSITY OF ARIZONA   (United States)

^b University of Arizona   (United States)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

^d UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

Allopregnanolone; Beta cyclodextrin; Brain; DTI; Dysmyelination; Mouse; Neurodegeneration; Neurosteroids

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; 3ALPHA HYDROXY 5ALPHA PREGNAN 20 ONE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANISOTROPY; ARTICLE; AUTOPSY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIFFUSION TENSOR IMAGING; DRUG EFFICACY; DRUG RESPONSE; HISTOPATHOLOGY; IMAGE ANALYSIS; IN VIVO STUDY; MOUSE; MYELIN DEFICIENCY; MYELINATION; NERVE DEGENERATION; NEUROIMAGING; NIEMANN PICK DISEASE; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; WHITE MATTER; WILD TYPE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; DIFFUSION MAGNETIC RESONANCE IMAGING; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NIEMANN-PICK DISEASE, TYPE C; PREGNANOLONE; PROTEINS; WEANING;

EID: 55749114693     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21707     Document Type: Article

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