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Halder SL, Locke GR 3rd, Schleck CD, et al. Natural history of functional gastrointestinal disorders: a 12-year longitudinal population-based study. Gastroenterology 2007; 133:799-807. This study describes in detail the natural history of functional gastrointestinal disorders (FGIDs) and of IBS and functional dyspepsia, in particular, and demonstrates that, although the point prevalence of both IBS and functional dyspepsia remained stable over the 12-year study period, there was substantial movement from one diagnosis to the other over time.
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Halder SL, Locke GR 3rd, Schleck CD, et al. Natural history of functional gastrointestinal disorders: a 12-year longitudinal population-based study. Gastroenterology 2007; 133:799-807. This study describes in detail the natural history of functional gastrointestinal disorders (FGIDs) and of IBS and functional dyspepsia, in particular, and demonstrates that, although the point prevalence of both IBS and functional dyspepsia remained stable over the 12-year study period, there was substantial movement from one diagnosis to the other over time.
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2
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33644886030
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Detailed characterization of epidemiology of uninvestigated dyspepsia and its impact on quality of life among African-Americans as compared to Caucasians
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Minocha A, Wigington WC, Johnson WD. Detailed characterization of epidemiology of uninvestigated dyspepsia and its impact on quality of life among African-Americans as compared to Caucasians. Am J Gastroenterol 2006; 101:336-342.
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Minocha, A.1
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Influence of experimentally induced anxiety on gastric sensorimotor function in humans
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Geeraerts B, Vandenberghe J, Van Oudenhove L, et al. Influence of experimentally induced anxiety on gastric sensorimotor function in humans. Gastroenterology 2005; 129:1437-1444.
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Wildner-Christensen M, Hansen JM, De Muckadell OB. Risk factors for dyspepsia in a general population: nonsteroidal anti-inflammatory drugs, cigarette smoking and unemployment are more important than Helicobacter pylori infection. Scand J Gastroenterol 2006;41:149-154.
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This study identifies factors which lead an individual with dyspepsia to seek medical care
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and for the Canadian Dyspepsia Working Group
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Can the clinical history distinguish between organic and functional dyspepsia?
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Choung RS, Locke GR, Schleck CD, et al. Do distinct dyspepsia subgroups exist in the community? A population-based study. Am J Gastroenterol 2007; 102:1983-1989.
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33846929206
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Hiyama T, Yoshihara M, Matsuo K, et al. Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia. J Gastroenterol Hepatol 2007; 22:304-310. This study nicely summarizes the frustrations of prokinetic studies in functional dyspepsia; overall there is no benefit for prokinetics; some individual drugs show some modest benefits.
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Choung RS, Cremonini F, Thapa P, et al. The effect of short-term, low-dose tricyclic and tetracyclic antidepressant treatment on satiation, postnutrient load gastrointestinal symptoms and gastric emptying: a double-blind, randomized, placebo-controlled trial. Neurogastroenterol Motil 2008; 20:220-227.
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26
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34247636712
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This study extends observations made with advanced imaging techniques in IBS to functional dyspepsia
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Vandenberghe J, Dupont P, Van Oudenhove L, et al. Regional cerebral blood flow during gastric balloon distension in functional dyspepsia. Gastroenterology 2007; 132:1684-1693. This study extends observations made with advanced imaging techniques in IBS to functional dyspepsia.
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From data generated in a population study in Sweden, the authors report a significant association between duodenal mucosal eosinophilia and dyspepsia
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Pilichiewicz, A.N.1
Horowitz, M.2
Russo, A.3
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