The influence of the novel 5-HT1A agonist R137696 on the proximal stomach function in healthy volunteers

Neurogastroenterology and Motility

Volumn 18, Issue 10, 2006, Pages 919-926

  Boeckxstaens, G E ^a   Tytgat, G N ^a   Wajs, E ^b   Van Nueten, L ^b   De Ridder, F ^b   Meulemans, A ^b   Tack, J ^c  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^c UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

5 HT1A agonist; Accommodation; Dyspepsia; Fundic relaxation; Proximal stomach; Visceral perception

Indexed keywords

1 (2 METHOXYPHENYL) 4 (4 PHTHALIMIDOBUTYL)PIPERAZINE; N [4 METHOXY 3 (4 METHYL 1 PIPERAZINYL)PHENYL] 2' METHYL 4' (5 METHYL 1,2,4 OXADIAZOL 3 YL)[1,1' BIPHENYL] 4 CARBOXAMIDE; PLACEBO; R 137696; SEROTONIN 1A AGONIST;

ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG INHIBITION; DRUG MECHANISM; DRUG SYNTHESIS; DYSPEPSIA; HUMAN; HUMAN EXPERIMENT; LOGISTIC REGRESSION ANALYSIS; MALE; NAUSEA; NORMAL HUMAN; PRIORITY JOURNAL; SATIETY; SENSORIMOTOR FUNCTION; STOMACH DISCOMFORT; STOMACH DISTENSION; STOMACH FUNCTION; STOMACH PAIN; VISUAL ANALOG SCALE;

ADULT; COMPLIANCE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; HUMANS; MALE; MANOMETRY; MUSCLE RELAXATION; MUSCLE, SMOOTH; PAIN MEASUREMENT; SEROTONIN AGONISTS; STOMACH;

EID: 33748507784     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2006.00812.x     Document Type: Article

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