In-practice predictors of response to proton pump inhibitor therapy in primary care patients with dyspepsia in an Asian population

Journal of Clinical Gastroenterology

Volumn 42, Issue 2, 2008, Pages 134-138

  Gwee, Kok Ann ^a,b   Hwang, Joel Ern Huei ^a   Ho, Khek Yu ^a   Yeoh, Khay Guan ^a   Lum, Chun Fatt ^a   Ang, Poh Kit ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b GLENEAGLES HOSPITAL   (Singapore)

Author keywords

Bloating; Dyspepsia; Gastroesophageal reflux; Irritable bowel syndrome; Primary care; Proton pump inhibitor

Indexed keywords

ANTICOAGULANT AGENT; ESOMEPRAZOLE; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

AGED; ANXIETY; ARTICLE; BLOATING; CLINICAL FEATURE; CONTROLLED STUDY; DYSPEPSIA; ENDOSCOPY; FEMALE; GENERAL PRACTITIONER; HUMAN; IRRITABLE COLON; MAJOR CLINICAL STUDY; MALE; MEDICAL PRACTICE; PEPTIC ULCER; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; TREATMENT DURATION; TREATMENT FAILURE; TREATMENT RESPONSE;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; DYSPEPSIA; FEMALE; HUMANS; MALE; MIDDLE AGED; OMEPRAZOLE; PREDICTIVE VALUE OF TESTS; PRIMARY HEALTH CARE; PROSPECTIVE STUDIES; PROTON PUMP INHIBITORS; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 38349128834     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mcg.0000225620.02094.c3     Document Type: Article

References (21)

1. Swarbrick ET, Hegarty JE, Bat L, et al. Site of pain from the irritable bowel. Lancet. 1980;2:443-446.
2. Klauser AG, Schindlbeck NE, Muller-Lissner SA. Symptoms in gastro-oesophageal reflux disease. Lancet. 1990;335:205-208.
3. Fennerty MB. Use of antisecretory agents as a trial of therapy. Gut. 2002;50(suppl IV):iv63-iv66.
4. Vakil N. Review article: how valuable are proton-pump inhibitors in establishing a diagnosis of gastro-oesophageal reflux disease? Aliment Pharmacol Ther. 2005;22(suppl 1):64-69.
5. Talley NJ, Meineche-Schmidt V, Pare P, et al. Efficacy of omeprazole in functional dyspepsia: double-blind, randomized, placebo-controlled trials (the Bond and Opera studies). Aliment Pharmacol Ther. 1998;12:1055-1065.
6. Ho KY, Kang JY, Seow A. Prevalence of gastrointestinal symptoms in a multi-racial Asian population, with particular reference to reflux-type symptoms. Am J Gastroenterol. 1998;93:1816-1822.
7. Kang JY, Ho KY. Different prevalences of reflux oesophagitis and hiatus hernia among dyspeptic patients in England and Singapore. Eur J Gastroenterol Hepatol. 1999;11:845-850.
8. Wong WM, Wong BC, Hung WK, et al. Double blind, randomized, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients. Gut. 2002;51:502-506.
9. Gwee KA, Wee S, Wong ML, et al. The prevalence, symptom characteristics, and impact of irritable bowel syndrome in an asian urban community. Am J Gastroenterol. 2004;99:924-931.
10. Yeoh KG, Kang JY, Tay HH, et al. Effect of cisapride on functional dyspepsia in patients with and without histological gastritis: a double-blind placebo-controlled trial. J Gastroenterol Hepatol. 1997;12:13-18.
11. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983;67:361-370.
12. Thompson WG, Longstreth GF, Drossman DA, et al. Functional bowel disorders and functional abdominal pain. Gut. 1999;45(suppl II):II43-II47.
13. Bolling-Sternevald E, Lauritsen K, Aalykke C, et al. Effect of profound acid suppression in functional dyspepsia: a double-blind, randomized, placebo-controlled trial. Scand J Gastroenterol. 2002;37:1395-1402.
14. Talley NJ, Dennis EH, Schettler-Duncan VA, et al. Overlapping upper and lower gastrointestinal symptoms in irritable bowel syndrome patients with constipation or diarrhoea. Am J Gastroenterol. 2003;98:2454-2459.
15. Serra J, Azpiroz F, Malagelada JR. Impaired transit and tolerance of intestinal gas in the irritable bowel syndrome. Gut. 2001;48:14-19.
16. Salvioli B, Serra J, Azpiroz F, et al. Origin of gas retention in patients with bloating. Gastroenterology. 2005;128:574-579.
17. Talley NJ, Zinsmeister AR, Schleck CD, et al. Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology. 1992;10:1259-1268.
18. Van Bommel MJJ, Numans ME, de Wit NJ, et al. Consultations and referrals for dyspepsia in general practice - a one year database survey. Postgrad Med J. 2001;77:514-518.
19. Corsetti M, Caenepeel P, Fischler B, et al. Impact of coexisting irritable bowel syndrome on symptoms and pathophysiological mechanisms in functional dyspepsia. Am J Gastroenterol. 2004;99:1152-1159.
20. Bolling-Sternevald E, Lauritsen K, Talley NJ, et al. Is it possible to predict treatment response to a proton pump inhibitor in functional dyspepsia? Aliment Pharmacol Ther. 2003;18:117-124.
21. Gwee KA. Irritable bowel syndrome in developing countries - disorder of civilization or colonization? Neurogastroenterol Motil. 2005;17:317-324.