Comparison of molecular mobility in the glassy state between amorphous indomethacin and salicin based on spin-lattice relaxation times

Pharmaceutical Research

Volumn 22, Issue 5, 2005, Pages 797-805

  Masuda, Katsuhiko ^a,b   Tabata, Sachio ^c   Sakata, Yasuyuki ^c   Hayase, Tetsuo ^d   Yonemochi, Etsuo ^a   Terada, Katsuhide ^a  

^a TOHO UNIVERSITY   (Japan)

^b Discovery Technology   (Finland)

^c MITSUBISHI CHEMICAL CORPORATION   (Japan)

^d MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

Amorphous indomethacin; Amorphous salicin; Molecular mobility; Solid state 13C NMR; Spin lattice relaxation times (T1c)

Indexed keywords

CARBON; INDOMETACIN; SALICIN;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DISPERSION; DRUG STABILITY; DRUG STRUCTURE; GLASS TRANSITION TEMPERATURE; MATHEMATICAL COMPUTING; POLARIZATION; PRIORITY JOURNAL;

BENZYL ALCOHOLS; CARBON ISOTOPES; CHEMISTRY, PHARMACEUTICAL; CRYSTALLIZATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; INDOMETHACIN; MOLECULAR CONFORMATION; MOTION; POWDERS; TEMPERATURE; TIME FACTORS;

EID: 20044372752     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11095-005-2597-4     Document Type: Article

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