A new approach to search for the bioactive conformation of glucagon: Positional cyclization scanning

Journal of Medicinal Chemistry

Volumn 44, Issue 19, 2001, Pages 3109-3116

  Ahn, J M ^a   Gitu, P M ^a   Medeiros, M ^a   Swift, J R ^a   Trivedi, D ^a   Hruby, V J ^a  

^a University of Arizona   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLO[17 LYSINE 21 GLUTAMIC ACID]GLUCAGONAMIDE; CYCLO[5 LYSINE 9 GLUTAMIC ACID]GLUCAGONAMIDE; CYSTEINE; GLUCAGON DERIVATIVE; GLUCAGON RECEPTOR; GLUTAMIC ACID; LACTAM DERIVATIVE; LYSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CYCLIZATION; DISULFIDE BOND; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HORMONE RECEPTOR INTERACTION; HORMONE STRUCTURE; LIVER MEMBRANE; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; SIGNAL TRANSDUCTION;

ADENYLATE CYCLASE; AMINO ACID SEQUENCE; CELL MEMBRANE; CIRCULAR DICHROISM; DISULFIDES; GLUCAGON; LACTAMS; LIVER; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; RADIOLIGAND ASSAY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0035855890     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm010091q     Document Type: Article

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