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Rivera E, Wahle A, Joswick TR, Ueno R. Lubiprostone, a novel type-2 chloride channel (CIC-2) activator, does not affect serum electrolyte balance in elderly and nonelderly patients with chronic idiopathic constipation. Gastroenterology 132(4 Suppl. 2), A191 (2007) (Abstract).
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Engelke K, Harris S, Roerig B, Ueno R. Effect of lubiprpstone, a novel type-2 chloride channel (CIC-2) activator, in pregnant rhesus monkeys. Gastroenterology 132(4 Suppl. 2), A534 (2007) (Abstract).
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Moeser AJ, Nighot PK, Engelke KJ, Ueno R, Blikslager AT. Recovery of mucosal barrier function in ischemic porcine ileum and colon is stimulated by a novel agonist of the CIC-2 chloride channel, lubiprostone. Am. J. Physiol. Gastrointest. Liver Physiol. 292(2), G647-656 (2007).
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