Activation of p70(S6) kinase by β-adrenoceptor agonists on adult cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 30, Issue 10, 1998, Pages 2059-2067

  Simm, Andreas ^a   Schluter K D ^b   Diez, C ^a   Piper, H M ^b   Hoppe, J ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Cardiomyocytes; Hypertrophy; p70(S6) kinase; Rapamycin; Rat

Indexed keywords

BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOTRANSFERASE; RAPAMYCIN;

ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CELL GROWTH; CONTROLLED STUDY; ENZYME ACTIVATION; GROWTH REGULATION; HEART HYPERTROPHY; HEART MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; RAT; RNA ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0032190906     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmcc.1998.0768     Document Type: Article

References (25)

1. BARTOLOME J, HUGUENARD J, SLOTKIN TA, 1980. Role of ornithine decarboxylase in cardiac growth and hypertrophy. Science 210: 793-794.
2. BOGOYEVITCH MA, ANDERSSON MB, GILLESPIE BROWN J, CLERK A, GLENNON PE, FULLER SJ, SUGDEN PH, 1996. Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy. Biochem J 314: 115-121.
3. BOLUYT MO, ZHENG JS, YOUNES A, LONG X, O'NEILL L, SILVERMAN H, LAKATTA EG, CROW MT, 1997. Rapamycin inhibits alpha 1-adrenergic receptor-stimulated cardiac myocyte hypertrophy but not activation of hypertrophy-associated genes. Evidence for involvement of p70S6 kinase. Circ Res 81: 176-186.
4. BRADFORD MM, 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
5. DE GROOT RP, BALLOU KM, SASSONE CORSI P, 1994. Positive regulation of the cAMP-responsive activator CREM by the p70S6 kinase: an alternative route to mitogen-induced gene expression. Cell 79: 81-91.
6. ERIKSON RL, 1991. Structure, expression, and regulation of protein kinases involved in the phosphorylation of ribosomal protein S6. J Biol Chem 266: 6007-6010.
7. FULLER SJ, GAITANAKI CJ, SUGDEN PH, 1990. Effects of catecholamines on protein synthesis in cardiac myocytes and perfused hearts isolated from adult rats. Stimulation of translation is mediated through the alpha 1-adrenoceptor. Biochem J 266: 727-736.
8. GILES KW, MYERS A, 1965. An improved diphenylamine method for the estimation method for the estimation of desoxyribonucleic acid. Nature 206: 93.
9. JEFFERIES HB, REINHARD C, KOZMA SC, THOMAS G, 1994. Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family. Proc Natl Acad Sci USA 91: 4441-4445.
10. LEICHT M, SIMMA, BERTSCH G, HOPPE J, 1996. Okadaic acid induces cellular hypertrophy in AKR-2B fibroblasts: involvement of the p70S6 kinase in the onset of protein and rRNA synthesis. Cell Growth Diff 7: 1199-1209.
11. LIN TA, LAWRENCE JC, 1996. Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes. J Biol Chem 271: 30199-30204.
12. MCDERMOTT PJ, ROTHBLUM LI, SMITH SD, MORGAN HE, 1989. Accelerated rates of ribosomal RNA synthesis during growth of contracting heart cells in culture. J Biol Chem 264: 18220-18227.
13. MONFAR M, LEMON KP, GRAMMER TC, CHEATHAM L, CHUNG J, VLAHOS CJ, BLENIS J, 1995. Activation of pp70/85 S6 kinases in interleukin-2-responsive lymphoid cells is mediated by phosphatidylinositol 3-kinase and inhibited by cAMP. Mol Cell Biol 15: 326-337.
14. PEARSON RB, DENNIS PB, HAN JW, WILLIAMSON NA, KOZMA SC, WETTENHALL RE, THOMAS G, 1995. The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain. EMBO J 14: 5279-5287.
15. PINSON A, SCHLÜTER KD, ZHOU XJ, SCHWARTZ P, KESSLER-ICEKSON G, PIPER HM, 1993. Alpha-and beta-adrenergic stimulation of protein synthesis in cultured adult ventricular cardiomyocytes. J Mol Cell Cardiol 25: 477-490.
16. PIPER HM, VOLZ A, SCHWARTZ P, 1990. Adult Ventricular Rat Heart Muscle Cells. In: Piper HM (ed.). Cell Culture Techniques in Heart and Vessel Research. 1st Ed. New York: Springer, 36-60.
17. SCHLÜTER KD, PIPER HM, 1992. Trophic effects of catecholamines and parathyroid hormone on adult ventricular cardiomyocytes. Am J Physiol 263: H1739-H1746.
18. SCHLÜTER KD, ZHOU XJ, PIPER HM, 1995. Induction of hypertrophic responsiveness to isoproterenol by TGF-beta in adult rat cardiomyocytes. Am J Physiol 269: C1311-C1316.
19. SIMM A, HOPPE V, TATJE D, SCHENZINGER A, HOPPE J, 1992. PDGF-AA effectively stimulates early events but has no mitogenic activity in AKR-2B mouse fibroblasts. Exp Cell Res 201: 192-199.
20. STEWART MJ, THOMAS G, 1994. Mitogenesis and protein synthesis: a role for ribosomal protein S6 phosphorylation? Bioessays 16: 809-815.
21. SUSA M, VULEVIC D, LANE HA, THOMAS G, 1992. Inhibition or down-regulation of protein kinase C attenuates late phase p70s6k activation induced by epidermal growth factor but not by platelet-derived growth factor or insulin. J Biol Chem 267: 6905-6909.
22. WALLENSTEIN S, ZUCKER CL, FLEISS JL, 1980. Some statistical methods useful in circulation research. Circ Res 47: 1-9.
23. WITHERS DJ, 1997. Signalling pathways involved in the mitogenic effects of cAMP. Clin Sci Colch 92: 445-451.
24. YAMAZAKI T, KOMURO I, YAZAKI Y, 1995. Molecular mechanism of cardiac cellular hypertrophy by mechanical stress. J Mol Cell Cardiol 27: 133-140.
25. ZHOU XJ, SCHLÜTER KD, PIPER HM, 1996. Hypertrophic responsiveness to beta 2-adrenoceptor stimulation on adult ventricular cardiomyocytes. Mol Cell Biochem 163-164: 211-216.