-
1
-
-
0034836597
-
Amino acids and insulin are both required to regulate assembly of eIF4E·eIF4G complex in rat skeletal muscle
-
Balage M, Sinaud S, Prod'Homme M et al (2001) Amino acids and insulin are both required to regulate assembly of eIF4E·eIF4G complex in rat skeletal muscle. Am J Physiol Endocrinol Metab 281:E565-E574
-
(2001)
Am J Physiol Endocrinol Metab
, vol.281
-
-
Balage, M.1
Sinaud, S.2
Prod'Homme, M.3
-
2
-
-
0036081155
-
Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine
-
Anthony JC, Lang CH, Crozier SJ et al (2002) Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine. Am J Physiol Endocrinol Metab 282:E1092-E1101
-
(2002)
Am J Physiol Endocrinol Metab
, vol.282
-
-
Anthony, J.C.1
Lang, C.H.2
Crozier, S.J.3
-
3
-
-
0037108750
-
Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling
-
doi: 10.1073/pnas.202476899
-
Tee AR, Fingar DC, Manning BD et al (2002) Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling. Proc Natl Acad Sci USA 99:13571-13576. doi: 10.1073/pnas.202476899
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13571-13576
-
-
Tee, A.R.1
Fingar, D.C.2
Manning, B.D.3
-
4
-
-
7144255533
-
Interaction between humartrin and tuberlin, the TSC1 and TSC2 gene products
-
doi: 10.1093/hmg/7.6.1053
-
van Slegtenhorst M, Nellist M, Nagelkerken B et al (1998) Interaction between humartrin and tuberlin, the TSC1 and TSC2 gene products. Hum Mol Genet 7:1053-1057. doi: 10.1093/hmg/7.6.1053
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1053-1057
-
-
van Slegtenhorst, M.1
Nellist, M.2
Nagelkerken, B.3
-
5
-
-
0038433304
-
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and TSC2
-
doi: 10.1016/S1097-2765(03)00220-X
-
Garami A, Zwartkruis FJT, Nobukuni T et al (2003) Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and TSC2. Mol Cell 11:1457-1466. doi: 10.1016/S1097-2765(03)00220-X
-
(2003)
Mol Cell
, vol.11
, pp. 1457-1466
-
-
Garami, A.1
Zwartkruis, F.J.T.2
Nobukuni, T.3
-
6
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
doi: 10.1038/ncb839
-
Inoki K, Li Y, Zhu T et al (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4:648-657. doi: 10.1038/ncb839
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
-
7
-
-
0038141979
-
Rheb is a direct target of the tuberous sclerosis tumor supressor proteins
-
doi: 10.1038/ncb999
-
Zhang Y, Gao X, Saucedo L et al (2003) Rheb is a direct target of the tuberous sclerosis tumor supressor proteins. Nat Cell Biol 5:578-581. doi: 10.1038/ncb999
-
(2003)
Nat Cell Biol
, vol.5
, pp. 578-581
-
-
Zhang, Y.1
Gao, X.2
Saucedo, L.3
-
8
-
-
18544375193
-
Phosphotidylinositol 3-kinase/AKT pathway regulates tuberous sclerosis tumor supressor complex by phosphorylation of tuberin
-
doi: 10.1074/jbc.M205838200
-
Dan HC, Sun M, Yang L et al (2002) Phosphotidylinositol 3-kinase/AKT pathway regulates tuberous sclerosis tumor supressor complex by phosphorylation of tuberin. J Biol Chem 277:35364-35370. doi: 10.1074/ jbc.M205838200
-
(2002)
J Biol Chem
, vol.277
, pp. 35364-35370
-
-
Dan, H.C.1
Sun, M.2
Yang, L.3
-
9
-
-
0036342294
-
Identification of the tuberous sclerosis complex-2 tumor supressor gene product tuberlin as a target of the phosphoinositide 3-kinase/Akt pathway
-
doi: 10.1016/S1097-2765(02)00568-3
-
Manning BD, Tee AR, Logsdon MN et al (2002) Identification of the tuberous sclerosis complex-2 tumor supressor gene product tuberlin as a target of the phosphoinositide 3-kinase/Akt pathway. Mol Cell 10:151-162. doi: 10.1016/S1097-2765(02)00568-3
-
(2002)
Mol Cell
, vol.10
, pp. 151-162
-
-
Manning, B.D.1
Tee, A.R.2
Logsdon, M.N.3
-
10
-
-
20944444016
-
IGF-I activates the eIF4F system in cardiac muscle in vivo
-
doi: 10.1007/s11010-005-7551-6
-
Vary TC, Lang CH (2005) IGF-I activates the eIF4F system in cardiac muscle in vivo. Mol Cell Biochem 272:209-220. doi: 10.1007/ s11010-005-7551-6
-
(2005)
Mol Cell Biochem
, vol.272
, pp. 209-220
-
-
Vary, T.C.1
Lang, C.H.2
-
11
-
-
33748302991
-
Meal feeding stimulates phosphorylation of multiple effector proteins regulating protein synthetic processes in rat hearts
-
Vary TC, Lynch CJ (2006) Meal feeding stimulates phosphorylation of multiple effector proteins regulating protein synthetic processes in rat hearts. J Nutr 136:2284-2290
-
(2006)
J Nutr
, vol.136
, pp. 2284-2290
-
-
Vary, T.C.1
Lynch, C.J.2
-
12
-
-
33646079646
-
Meal feeding enhances formation of eIF4F in skeletal muscle: Role of increased eIF4E availability and eIF4G phosphorylation
-
doi: 10.1152/ajpendo.00460.2005
-
Vary TC, Lynch CJ (2006) Meal feeding enhances formation of eIF4F in skeletal muscle: Role of increased eIF4E availability and eIF4G phosphorylation. Am J Physiol Endocrinol Metab 290:E631-E642. doi: 10.1152/ajpendo.00460.2005
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
-
-
Vary, T.C.1
Lynch, C.J.2
-
13
-
-
20944451539
-
Regulation of protein metabolism in muscle
-
In: Jefferson LS, Cherrington AD (eds) Oxford University Press, New York
-
Jefferson LS, Vary TC, Kimball SR (2001) Regulation of protein metabolism in muscle. In: Jefferson LS, Cherrington AD (eds) Handbook of physiology. Oxford University Press, New York, pp 529-552
-
(2001)
Handbook of Physiology
, pp. 529-552
-
-
Jefferson, L.S.1
Vary, T.C.2
Kimball, S.R.3
-
14
-
-
0029103330
-
Control of p70 S6 kinase by kinase activity of FRAP in vivo
-
doi: 10.1038/377441a0
-
Brown EJ, Beal PA, Keith CT et al (1995) Control of p70 S6 kinase by kinase activity of FRAP in vivo. Nature 377:441-446. doi: 10.1038/ 377441a0
-
(1995)
Nature
, vol.377
, pp. 441-446
-
-
Brown, E.J.1
Beal, P.A.2
Keith, C.T.3
-
15
-
-
0035912780
-
The target of rapamycin (TOR) proteins
-
doi: 10.1073/pnas.121145898
-
Raught B, Gingas A-C, Sonenberg N (2001) The target of rapamycin (TOR) proteins. Proc Natl Acad Sci USA 98:7037-7044. doi: 10.1073/ pnas.121145898
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 7037-7044
-
-
Raught, B.1
Gingas, A.-C.2
Sonenberg, N.3
-
16
-
-
0034234924
-
A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells
-
Sekulic A, Hudson CC, Homme JL et al (2000) A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells. Cancer Res 60:3504-3513
-
(2000)
Cancer Res
, vol.60
, pp. 3504-3513
-
-
Sekulic, A.1
Hudson, C.C.2
Homme, J.L.3
-
17
-
-
0034629365
-
FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions
-
doi: 10.1074/jbc.275.10.7416
-
Peterson RT, Beal PA, Comb MJ et al (2000) FKBP12-rapamycin-associated protein (FRAP) autophosphorylates at serine 2481 under translationally repressive conditions. J Biol Chem 275:7416-7423. doi: 10.1074/ jbc.275.10.7416
-
(2000)
J Biol Chem
, vol.275
, pp. 7416-7423
-
-
Peterson, R.T.1
Beal, P.A.2
Comb, M.J.3
-
18
-
-
25144486927
-
Nutrient signaling to muscle and adipose tissue by leucine
-
In: Zempleni J, Dakshinamirti K (eds) CRC Press, Boca Raton, FL
-
Vary TC, Lynch CJ (2005) Nutrient signaling to muscle and adipose tissue by leucine. In: Zempleni J, Dakshinamirti K (eds) Nutrient and cell signaling. CRC Press, Boca Raton, FL, pp 299-352
-
(2005)
Nutrient and Cell Signaling
, pp. 299-352
-
-
Vary, T.C.1
Lynch, C.J.2
-
19
-
-
34548074950
-
Nutrient signaling components controlling protein synthesis in striated muscle
-
Vary TC, Lynch CJ (2007) Nutrient signaling components controlling protein synthesis in striated muscle. J Nutr 137:1835-1843
-
(2007)
J Nutr
, vol.137
, pp. 1835-1843
-
-
Vary, T.C.1
Lynch, C.J.2
-
20
-
-
34548083053
-
Rapamycin limits formation of active eukaryotic initiation factor 4F complex following meal feeding in rat hearts
-
Vary TC, Deiter G, Lynch CJ (2007) Rapamycin limits formation of active eukaryotic initiation factor 4F complex following meal feeding in rat hearts. J Nutr 137:1857-1862
-
(2007)
J Nutr
, vol.137
, pp. 1857-1862
-
-
Vary, T.C.1
Deiter, G.2
Lynch, C.J.3
-
21
-
-
3042701690
-
Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation
-
Bolster DR, Vary TC, Kimball SR et al (2004) Leucine regulates translation initiation in rat skeletal muscle via enhanced eIF4G phosphorylation. J Nutr 134:1704-1710
-
(2004)
J Nutr
, vol.134
, pp. 1704-1710
-
-
Bolster, D.R.1
Vary, T.C.2
Kimball, S.R.3
-
22
-
-
0033429554
-
Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation
-
doi: 10.1042/0264-6021:3440427
-
Nave BT, Owens M, Withers DJ et al (1999) Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation. Biochem J 344:427-431. doi: 10.1042/ 0264-6021:3440427
-
(1999)
Biochem J
, vol.344
, pp. 427-431
-
-
Nave, B.T.1
Owens, M.2
Withers, D.J.3
-
23
-
-
0031919552
-
Insulin signal transduction through protein kinase cascades
-
doi: 10.1023/A:1006823109415
-
Avruch J (1998) Insulin signal transduction through protein kinase cascades. Mol Cell Biochem 182:31-42. doi: 10.1023/A:1006823109415
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 31-42
-
-
Avruch, J.1
-
24
-
-
0036714127
-
AKT regulates growth by directly phosphorylating TSC2
-
doi: 10.1038/ncb840
-
Potter CJ, Pedrazza LG, Xu T (2002) AKT regulates growth by directly phosphorylating TSC2. Nat Cell Biol 4:658-662. doi: 10.1038/ncb840
-
(2002)
Nat Cell Biol
, vol.4
, pp. 658-662
-
-
Potter, C.J.1
Pedrazza, L.G.2
Xu, T.3
-
25
-
-
37349097629
-
Chronic alcohol feeding impairs mTOR(Ser2448) phosphorylation in rat hearts
-
doi: 10.1111/j.1530-0277.2006.00285.x
-
Vary TC, Deiter G, Lantry R (2007) Chronic alcohol feeding impairs mTOR(Ser2448) phosphorylation in rat hearts. Alcohol Clin Exp Res 31:43-51. doi: 10.1111/j.1530-0277.2006.00285.x
-
(2007)
Alcohol Clin Exp Res
, vol.31
, pp. 43-51
-
-
Vary, T.C.1
Deiter, G.2
Lantry, R.3
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