Extraction of pure lycopene from industrial tomato by-products in water using a new high-pressure process

Journal of the Science of Food and Agriculture

Volumn 88, Issue 14, 2008, Pages 2414-2420

  Naviglio, Daniele ^a   Pizzolongo, Fabiana ^a   Ferrara, Lydia ^a   Aragòn, Alejandro ^b   Santini, Antonello ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b FACULTAD DE CIENCIAS AGRARIAS Y FORESTALES   (Argentina)

Author keywords

HPLC diode array; Lycopene; Naviglio extractor; NMR; Solid liquid extraction; Solid phase extraction; Tomato waste

Indexed keywords

CAPSICUM ANNUUM VAR. ANNUUM; CARICA PAPAYA; CITRULLUS LANATUS VAR. LANATUS; LYCOPERSICON ESCULENTUM;

EID: 55549128592     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.3334     Document Type: Article

References (26)

1. Sies H and Stahl W, Lycopene: antioxidant and biological effects and its bioavailability in the human. Proc Exp Biol Med 218:121-124 (1998).
2. Di Mascio P, Kaiser SP and Sies H, Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 274:179-185 (2002).
3. Lee MT and Chen BH, Stability of lycopene during heating and illumination in a model system. Food Chem 78:425-432 (2002).
4. Franceschi S, Bidoli E, La Vecchia C, Talamini R, D'Avanzo B and Negri E, Tomatoes and risk of digestive-tract cancers. Int J Cancer 59:181-184 (1994).
5. Giovannucci E, Tomatoes, tomato-based products, lycopene and cancer: review of the epidemiological literature. J Natl Cancer Inst 91:317-331 (1999).
6. Livny O, Kaplan I, Reifen R, Polak-Charcon S, Madar Z and Schwartz B, Lycopene inhibits proliferation and enhances gap-junction communication of KB-1 human oral tumor cells. J Nutr 132:3754-3759 (2002).
7. Heber D and Lu QY, Overview of mechanism of action of lycopene. Exp Biol Med 227:920-923 (2002).
8. Stacewicz-Sapuntzakis M and Bowen PE, Role of lycopene and tomato products in prostate health. Biochim Biophys Acta 1740:202-205 (2005).
9. Sthal W and Sies H, Lycopene: a biologically important carotenoid for humans? Arch Biochim Biophys 336:1-9 (1996).
10. Ulrich M, Business Report: The Global Market for Carotenoids. Business Communications, Norwalk, CT (2000).
11. Zhuo-cai L, Bo L, Hong Y and Zhi-rong C, Advances in research for chemical synthesis of lycopene. Hecheng Huaxue 14:118-121 (2006).
12. Montesano D, Fallarino F, Cossignani L, Bosi A, Simonetti MS, Puccetti P, et al, Innovative extraction procedure for obtaining high pure lycopene from tomato. Eur Food Res Technol 226:327-335 (2008).
13. Roldàn-Gutiérrez JM and Luque de Castro MD, Lycopene: the need for better methods for characterization and determination. Trends Anal Chem 26:163-170 (2007).
14. Rozzi NL, Singh RK, Vierling RA and Watkins BA, Supercritical fluid extraction of lycopene from tomato processing byproducts. J Agric Food Chem 50:2638-3643 (2002).
15. Olives Barba AI, Cámara Hurtado M, Sanchez Mata MC, Fernandez Ruiz V, Saenz de Tejada M and Lopez SD, Application of a UV-vis detection-HPLC method for a rapid determination of lycopene and β-carotene in vegetables. Food Chem 95:328-336 (2005).
16. Vági E, Simándi B, Vásárhelyine KP, Daood H, Kéry Á, Doleschall F, et al, Supercritical carbon dioxide extraction of carotenoids, tocopherols and sitosterols from industrial tomato by-products. J Supercrit Fluids 40:218-226 (2007).
17. Sandmann G, Carotenoid biosynthesis in microorganisms and plants. Eur J Biochem 223:7-24 (1994).
18. López-Nieto MJ, Costa J, Peiro E, Méndez E, Rodríguez-Sáiz M, de la Fuente JL, et al, Biotechnological lycopene production by mated fermentation of Blakeslea trispora. Appl Microbiol Biotechnol 66:153-159 (2004).
19. Naviglio D, Naviglio's principle and presentation of an innovative solid-liquid extraction technology: Extractor Naviglio®. Anal Lett 36:1647-1659 (2003).
20. Naviglio D, Rapid and dynamic solid-liquid extractor working at high pressures and low temperatures for obtaining in short times solutions containing substances that initially were in solid matrixes insoluble in extracting liquid. Italian Patent 1303417 (2000).
21. Naviglio D, Pizzolongo F, Romano R, Ferrara L, Naviglio B and Santini A, An innovative solid-liquid extraction technology: use of the Naviglio Extractor® for the production of lemon liquor. Afr J Food Sci 1:42-50 (2007).
22. Davis AR, Fish WW and Perkins-Veazie P, A rapid spectrophotometric method for analyzing lycopene content in tomato and tomato products. Postharvest Biol Technol 28:425-430 (2003).
23. Brumann T and Grimme LH, Reversed phase high performance liquid chromatography of chlorophylls and carotenoids. Biochem Biophys Acta 637:8-17 (1981).
24. Sadler G, Davis J and Deyman D, Rapid extraction of lycopene and beta-carotene from reconstituted tomato paste and pink grapefruit homogenates. J. Food Sci 55:1460-1465 (1990).
25. Wang CY and Chen BH, Tomato pulp as source for the production of lycopene powder containing high proportion of cis-isomers. Eur Food Res Technol 222:347-353 (2006).
26. Davis WB, Preparation of lycopene from tomato paste for use as a spectrophotometric standard. Anal Chem 21:1226-1228 (1949).