Applications of LC-MS to quantitation and evaluation of the environmental fate of chiral drugs and their metabolites

TrAC - Trends in Analytical Chemistry

Volumn 27, Issue 10, 2008, Pages 836-846

  Pérez, Sandra ^a   Barceló, Damià ^a,b  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b UNIVERSITY OF GIRONA   (Spain)

Author keywords

Chiral drug; Chirality; Emerging pollutant; Environmental analysis; Environmental fate; LC MS2; Mass spectrometric analyzer; Metabolite; Pharmaceutical degradation; Source of contamination

Indexed keywords

BIOMOLECULES; CHIRALITY; CHROMATOGRAPHIC ANALYSIS; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; METABOLITES; SPECTROMETERS; SPECTROMETRY; STEREOCHEMISTRY;

CHIRAL DRUG; EMERGING POLLUTANT; ENVIRONMENTAL ANALYSIS; ENVIRONMENTAL FATE; LC-MS2; MASS SPECTROMETRIC ANALYZER; PHARMACEUTICAL DEGRADATION; SOURCE OF CONTAMINATION;

ENANTIOMERS;

5 HYDROXYPROPAFENONE; AMFEBUTAMONE; AMIDE; ATENOLOL; CITALOPRAM; DRUG METABOLITE; FLUOXETINE; GEMFIBROZIL; IBUPROFEN; IFOSFAMIDE; KETAMINE; METOPROLOL; MIRTAZAPINE; NADOLOL; NAPROXEN; O NORTRAMADOL; OMEPRAZOLE; OMEPRAZOLE DERIVATIVE; OPIATE DERIVATIVE; PHENPROCOUMON; PINDOLOL; PROPAFENONE; PROPRANOLOL DERIVATIVE; RADAFAXINE; SALBUTAMOL; SULFONE DERIVATIVE; TRAMADOL; UNINDEXED DRUG; XENOBIOTIC AGENT;

ARTICLE; CHIRAL CHROMATOGRAPHY; CHIRALITY; DRUG MARKETING; DRUG SCREENING; DRUG SELECTIVITY; ENANTIOMER; ENANTIOSELECTIVITY; ENVIRONMENTAL IMPACT; HUMAN; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITE; METHODOLOGY; PRIORITY JOURNAL; RACEMIC MIXTURE; SENSITIVITY ANALYSIS; STEREOCHEMISTRY;

EID: 55549128189     PISSN: 01659936     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.trac.2008.09.003     Document Type: Article

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