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Volumn 383, Issue 6, 2005, Pages 909-917

Stereospecific pharmacokinetic characterisation of phenprocoumon metabolites, and mass-spectrometric identification of two novel metabolites in human plasma and liver microsomes

(6) Kammerer, Bernd a Kahlich, Rainer a Ufer, Mike c Schenkel, Andreas b Laufer, Stefan b Gleiter, Christoph H a

a UNIVERSITY HOSPITAL TÜBINGEN (Germany)

b UNIVERSITY OF TÜBINGEN (Germany)

c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN (Germany)

Author keywords

Chiral discrimination effects; LC MS coupling; Phenprocoumon metabolism

Indexed keywords

BIOLOGICAL ORGANS; COAGULATION; ENZYMES; PLASMAS;

ANTICOAGULATION; LC-MS COUPLING;

BIOCHEMISTRY;

ANTICOAGULANT AGENT; CYP2C9 PROTEIN, HUMAN; DRUG DERIVATIVE; PHENPROCOUMON; UNSPECIFIC MONOOXYGENASE;

AREA UNDER THE CURVE; ARTICLE; BLOOD; CHEMISTRY; ENZYMOLOGY; HUMAN; HYDROXYLATION; LIVER MICROSOME; MASS SPECTROMETRY; METABOLISM; STEREOISOMERISM;

ANTICOAGULANTS; AREA UNDER CURVE; ARYL HYDROCARBON HYDROXYLASES; HUMANS; HYDROXYLATION; MASS SPECTROMETRY; MICROSOMES, LIVER; PHENPROCOUMON; STEREOISOMERISM;

EID: 27744445060 PISSN: 16182642 EISSN: 16182650 Source Type: Journal
DOI: 10.1007/s00216-005-0113-7 Document Type: Article

Times cited : (15)

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