Molecular signatures of metastasis in head and neck cancer

Head and Neck

Volumn 30, Issue 10, 2008, Pages 1273-1283

  Colella, Stefano ^a,b,c   Richards, Kristy L ^a,d   Bachinski, Linda L ^a   Baggerly, Keith A ^a   Tsavachidis, Spiridon ^a   Lang, James C ^b   Schuller, David E ^b   Krahe, Ralf ^a,b  

^a UNIVERSITY OF TEXAS   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c UA INRA 203   (France)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Expression profiling; Gene signatures; Head and neck cancer; Metastasis; Oncogenomics

Indexed keywords

AUTOTAXIN; CHEMOKINE RECEPTOR CXCR4; CYTOCHROME P450 1B1; STROMELYSIN; TRANSCRIPTION FACTOR RUNX2; TUMOR MARKER;

ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENETIC IDENTIFICATION; GENETIC REGULATION; HEAD AND NECK CANCER; HUMAN; HUMAN TISSUE; LYMPH NODE METASTASIS; PRIMARY TUMOR; PRIORITY JOURNAL; TUMOR GROWTH;

BIOPSY; CARCINOMA, SQUAMOUS CELL; FROZEN SECTIONS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; LYMPHATIC METASTASIS; TRANSCRIPTION, GENETIC;

EID: 55549127538     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.20871     Document Type: Article

References (53)

1. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
2. Chambers AF, Groom AC, MacDonald IC. Dissemination and growth of cancer cells in metastatic sites. Nat Rev Cancer 2002;2:563-572.
3. Gupta PB, Mani S, Yang J, Hartwell K, Weinberg RA. The evolving portrait of cancer metastasis. Cold Spring Harb Symp Quant Biol 2005;70:291-297.
4. Hahn WC, Weinberg RA. Rules for making human tumor cells. N Engl J Med 2002;347:1593-1603.
5. Fidler IJ. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nat Rev Cancer 2003;3:453-458.
6. Fidler IJ, Kripke ML. Metastasis results from preexisting variant cells within a malignant tumor. Science 1977;197:893-895.
7. Bernards R, Weinberg RA. A progression puzzle. Nature 2002;418:823.
8. van't Veer LJ, Dai H, van de Vijver MJ, et al. Gene expression profiling predicts clinical outcome of breast cancer. Nature 2002;415:530-536.
9. van de Vijver MJ, He YD, van't Veer LJ, et al. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002;347:1999-2009.
10. Ramaswamy S, Ross KN, Lander ES, Golub TR. A molecular signature of metastasis in primary solid tumors. Nat Genet 2003;33:49-54.
11. Buckhaults P. Gene expression determinants of clinical outcome. Curr Opin Oncol 2006;18:57-61.
12. Califano J, van der Riet P, Westra W, et al. Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 1996;56:2488-2492.
13. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med 2001;345:1890-1900.
14. Perez-Ordonez B, Beauchemin M, Jordan RC. Molecular biology of squamous cell carcinoma of the head and neck. J Clin Pathol 2006;59:445-453.
15. Mao L, Hong WK, Papadimitrakopoulou VA. Focus on head and neck cancer. Cancer Cells 2004;5:311-316.
16. Lothaire P, de Azambuja E, Dequanter D, et al. Molecular markers of head and neck squamous cell carcinoma: promising signs in need of prospective evaluation. Head Neck 2006;28:256-269.
17. Ferlito A, Rinaldo A, Devaney KO, et al. Prognostic significance of microscopic and macroscopic extracapsular spread from metastatic tumor in the cervical lymph nodes. Oral Oncol 2002;38:747-751.
18. Li C, Wong HW. Model-based analysis of oligonucleotide arrays: model validation, design issues and standard error application. Genome Biol 2001;2:1-11.
19. Li C, Wong WH. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci U S A 2001;98:31-36.
20. Lemon WJ, Palatini JJ, Krahe R, Wright FA. Theoretical and experimental comparisons of gene expression indexes for oligonucleotide arrays. Bioinformatics 2002;18:1470-1476.
21. Morris JS, Yin G, Baggerly KA, Wu C, Zhang L. Pooling information across different studies and oligonucleotide chip types to identify prognostic genes for lung cancer. In: Shoemaker JS, Lin JS, editors. Methods of microarray data analysis IV. New York: Springer-Verlag; 2005. pp 51-66.
22. Irizarry RA, Hobbs B, Collin F, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 2003;4:249-264.
23. Dong Y, Sui L, Watanabe Y, Sugimoto K, Tokuda M. Clinical relevance of cyclin B1 overexpression in laryngeal squamous cell carcinoma. Cancer Lett 2002;177:13-19.
24. Hassan KA, Ang KK, El-Naggar AK, et al. Cyclin B1 overexpression and resistance to radiotherapy in head and neck squamous cell carcinoma. Cancer Res 2002;62:6414-6417.
25. Xi S, Dyer KF, Kimak M, et al. Decreased STAT1 expression by promoter methylation in squamous cell carcinogenesis. J Natl Cancer Inst 2006;98:181-189.
26. Pramana J, Pimentel N, Hofland I, et al. Heterogeneity of gene expression profiles in head and neck cancer. Head Neck 2007:1083-1089.
27. Lu Y, Lemon W, Liu PY, et al. A gene expression signature predicts survival of patients with stage I non-small cell lung cancer. PLoS Medicine 2006;3:2229-2243.
28. Ramesh R, Ito I, Gopalan B, Saito Y, Mhashilkar AM, Chada S. Ectopic production of MDA-7/IL-24 inhibits invasion and migration of human lung cancer cells. Mol Ther 2004;9:510-518.
29. Zlotnik A. Chemokines and cancer. Int J Cancer 2006;119:2026-2029
30. Levine MD, Liotta LA, Stracke ML. Stimulation and regulation of tumor cell motility in invasion and metastasis. EXS 1995;74:157-179.
31. Chung CH, Parker JS, Karaca G, et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. Cancer Cells 2004;5:489-500.
32. Cromer A, Carles A, Millon R, et al. Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis. Oncogene 2004;23:2484-2498.
33. Roepman P, Wessels LF, Kettelarij N, et al. An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas. Nat Genet 2005;37:182-186.
34. O'Donnell RK, Kupferman M, Wei SJ, et al. Gene expression signature predicts lymphatic metastasis in squamous cell carcinoma of the oral cavity. Oncogene 2005;24:1244-1251.
35. Schmalbach CE, Chepeha DB, Giordano TJ, et al. Molecular profiling and the identification of genes associated with metastatic oral cavity/pharynx squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2004;130:295-302.
36. Hunter KD, Thurlow JK, Fleming J, et al. Divergent routes to oral cancer. Cancer Res 2006;66:7405-7413.
37. Roepman P, de Jager A, Groot Koerkamp MJ, Kummer JA, Slootweg PJ, Holstege FC. Maintenance of head and neck tumor gene expression profiles upon lymph node metastasis. Cancer Res 2006;66:11110-11114.
38. Giri U, Ashorn CL, Ramdas L, et al. Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation. Int J Radiat Oncol Biol Phys 2006;64:670-677.
39. Sotiriou C, Lothaire P, Dequanter D, Cardoso F, Awada A. Molecular profiling of head and neck tumors. Curr Opin Oncol 2004;16:211-214.
40. Weigelt B, Glas AM, Wessels LF, Witteveen AT, Peterse JL, van't Veer LJ. Gene expression profiles of primary breast tumors maintained in distant metastases. Proc Natl Acad Sci U S A 2003;100:15901-15905.
41. Belbin TJ, Singh B, Smith RV, et al. Molecular profiling of tumor progression in head and neck cancer. Arch Otolaryngol Head Neck Surg 2005;131:10-18.
42. Forastiere A, Koch W, Trotti A, Sidransky D. Head and neck cancer. N Engl J Med 2001;345:1890-1900.
43. Nam SW, Clair T, Campo CK, Lee HY, Liotta LA, Stracke ML. Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells. Oncogene 2000;19:241-247.
44. Kang Y, Siegel PM, Shu W, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003;3:537-549.
45. Tsuda H, Sekine K, Fujita K, Ligo M. Cancer prevention by bovine lactoferrin and underlying mechanisms - a review of experimental and clinical studies. Biochem Cell Biol 2002;80:131-136.
46. Kyriazanos ID, Tachibana M, Dhar DK, et al. Expression and prognostic significance of S100A2 protein in squamous cell carcinoma of the esophagus. Oncol Rep 2002;9:503-510.
47. Ellerhorst JA, Prieto VG, Ekmekcioglu S, et al. Loss of MDA-7 expression with progression of melanoma. J Clin Oncol 2002;20:1069-1074.
48. Rubin H. Selected cell and selective microenvironment in neoplastic development. Cancer Res 2001;61:799-807.
49. Matrisian LM, Cunha GR, Mohla S. Epithelial-stromal interactions and tumor progression: meeting summary and future directions. Cancer Res 2001;61:3844-3846.
50. Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature 2001;411:375-379.
51. Clark EA, Golub TR, Lander ES, Hynes RO. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 2000;406:532-535.
52. Chen Z, Zhang K, Zhang X, et al. Comparison of gene expression between metastatic derivatives and their poorly metastatic parental cells implicates crucial tumor-environment interaction in metastasis of head and neck squamous cell carcinoma. Clin Exp Metastasis 2003;20:335-342.
53. Hynes RO. Metastatic potential: generic predisposition of the primary tumor or rare, metastatic variants-or both? Cell 2003;113:821-823.