Molecular signatures associated with clinical outcome in patients with high-risk head-and-neck squamous cell carcinoma treated by surgery and radiation

International Journal of Radiation Oncology Biology Physics

Volumn 64, Issue 3, 2006, Pages 670-677

  Giri, Uma ^a   Ashorn, Cheryl L ^a   Ramdas, Latha ^a   Stivers, David N ^b   Coombes, Kevin ^b   El Naggar, Adel K ^b   Ang, K Kian ^b   Story, Michael D ^a,c  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Gene expression; Head and neck squamous cell carcinoma; Metastasis

Indexed keywords

DNA; GENETIC ENGINEERING; PATIENT TREATMENT; RADIATION; RADIOTHERAPY; SURGERY; TUMORS;

GENE EXPRESSION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; METASTASIS;

CELL CULTURE;

BRCA1 ASSOCIATED RING DOMAIN PROTEIN 1; BRCA2 PROTEIN; CANCER GROWTH FACTOR; CYCLIN DEPENDENT KINASE 3; EPHRIN RECEPTOR B4; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FIBROBLAST GROWTH FACTOR RECEPTOR 3; HISTONE DEACETYLASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR FKHR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR YY1;

ANGIOGENESIS; APOPTOSIS; ARTICLE; CANCER RECURRENCE; CANCER SURGERY; CANCER SUSCEPTIBILITY; CELL ADHESION; CELL CYCLE; CELL GROWTH; CELL HETEROGENEITY; CELL INTERACTION; CELL PROLIFERATION; DISEASE ASSOCIATION; DNA RECOMBINATION; DNA REPAIR; DNA REPLICATION; GENE CLUSTER; GENE CONTROL; GENE EXPRESSION; GENETIC ANALYSIS; HEAD AND NECK CARCINOMA; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER METASTASIS; LUNG METASTASIS; METASTASIS; MOUTH CARCINOMA; ONCOGENE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; TREATMENT OUTCOME;

CARCINOMA, SQUAMOUS CELL; CELL CYCLE; CELL PROLIFERATION; CELL SHAPE; DNA REPAIR; DNA REPLICATION; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; LYMPHATIC METASTASIS; NEOPLASM RECURRENCE, LOCAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 31844445993     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2005.08.032     Document Type: Article

References (40)

1. R.T. Greenlee, M.B. Hill-Harmon, T. Murray Cancer statistics, 2001 CA Cancer J Clin 51 2001 15 36
2. A. Jemal, A. Thomas, T. Murray Cancer statistics, 2002 CA Cancer J Clin 52 2002 23 47
3. R.J. Baatenburg de Jong, J. Hermans, J. Molenaar Prediction of survival in patients with head-and-neck cancer Head Neck 23 2001 718 724
4. G.A. Jeon, J.S. Lee, V. Patel Global gene expression profiles of human head-and-neck squamous carcinoma cell lines Int J Cancer 112 2004 249 258
5. P.K. Ha, N.E. Benoit, R. Yochem A transcriptional progression model for head-and-neck cancer Clin Cancer Res 9 2003 3058 3064
6. C.H. Chung, J.S. Parker, G. Karaca Molecular classification of head-and-neck squamous cell carcinomas using patterns of gene expression Cancer Cell 5 2004 489 500
7. D.B. Villaret, T. Wang, D. Dillon Identification of genes overexpressed in head-and-neck squamous cell carcinoma using a combination of complementary DNA subtraction and microarray analysis Laryngoscope 110 2000 374 381
8. T.J. Belbin, B. Singh, I. Barber Molecular classification of head-and-neck squamous cell carcinoma using cDNA microarrays Cancer Res 62 2002 1184 1190
9. F.X. Bosch, D. Ritter, C. Enders Head-and-neck tumor sites differ in prevalence and spectrum of p53 alterations but these have limited prognostic value Int J Cancer 111 2004 530 538
10. F. Lemaire, R. Millon, J. Young Differential expression profiling of head-and-neck squamous cell carcinoma (HNSCC) Br J Cancer 89 2003 1940 1949
11. B. Singh, S.H. Kim, J.F. Carew Genome-wide screening for radiation response factors in head-and-neck cancer Laryngoscope 110 2000 1251 1256
12. K.A. Hartmann, O. Modlich, H.B. Prisack Gene expression profiling of advanced head-and-neck squamous cell carcinomas and two squamous cell carcinoma cell lines under radio/chemotherapy using cDNA arrays Radiother Oncol 63 2002 309 320
13. G.C. Warner, P.P. Reis, I. Jurisica Molecular classification of oral cancer by cDNA microarrays identifies overexpressed genes correlated with nodal metastasis Int J Cancer 110 2004 857 868
14. K.K. Ang, A. Trotti, B.W. Brown Randomized trial addressing risk features and time factors of surgery plus radiotherapy in advanced head-and-neck cancer Int J Radiat Oncol Biol Phys 51 2001 571 578
15. S. Pounds, S.W. Morris Estimating the occurrence of false positives and false negatives in microarray studies by approximating and partitioning the empirical distribution of p-values Bioinformatics 19 2003 1236 1242
16. M. Hendrickson, M. Madine, S. Dalton Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex Proc Natl Acad Sci USA 93 1996 12223 12228
17. J. Sage The RB gene family and control of the cell cycle Bull Cancer 88 2001 541 543
18. B.K. Nordskog, A.D. Blixt, W.T. Morgan Matrix-degrading and pro-inflammatory changes in human vascular endothelial cells exposed to cigarette smoke condensate Cardiovasc Toxicol 3 2003 101 117
19. T. Hirano The ABCs of SMC proteins Two-armed ATPases for chromosome condensation, cohesion, and repair Genes Dev 16 2002 399 414
20. J.P. Vaughn, F.D. Cirisano, G. Huper Cell cycle control of BRCA2 Cancer Res 56 1996 4590 4594
21. P. Zhu, E. Huber, F. Kiefer Specific and redundant functions of histone deacetylases in regulation of cell cycle and apoptosis Cell Cycle 3 2004 1240 1242
22. S. Hapke, H. Kessler, B. Luber Ovarian cancer cell proliferation and motility is induced by engagement of integrin alpha(v)beta3/vitronectin interaction Biol Chem 384 2003 1073 1083
23. Y. Mitsuuchi, S.W. Johnson, G. Sonoda Identification of a chromosome 3p14.3-21.1 gene, APPL, encoding an adaptor molecule that interacts with the oncoprotein-serine/threonine kinase AKT2 Oncogene 18 1999 4891 4898
24. M. Musat, V.V. Vax, N. Borboli Cell cycle dysregulation in pituitary oncogenesis Front Horm Res 32 2004 34 62
25. I. Irminger-Finger, J.V. Soriano, G. Vaudan In vitro repression of Brca1-associated RING domain gene, Bard1, induces phenotypic changes in mammary epithelial cells J Cell Biol 143 1998 1329 1339
26. J.A. Mello, H.H. Sillje, D.M. Roche Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway EMBO Rep 3 2002 329 334
27. C.L. Peterson, J. Cote Cellular machineries for chromosomal DNA repair Genes Dev 18 2004 602 616
28. B.B. Aggarwal Nuclear factor-kappaB The enemy within Cancer Cell 6 2004 203 208
29. W.X. Zong, J. Bash, C. Gelinas Rel blocks both anti-Fas- and TNF alpha-induced apoptosis and an intact Rel transactivation domain is essential for this effect Cell Death Differ 5 1998 963 972
30. F.G. Ondrey, G. Dong, J. Sunwoo Constitutive activation of transcription factors NF-(kappa)B, AP-1, and NF-IL6 in human head-and-neck squamous cell carcinoma cell lines that express pro-inflammatory and pro-angiogenic cytokines Mol Carcinog 26 1999 119 129
31. T. Kato, D.C. Duffey, F.G. Ondrey Cisplatin and radiation sensitivity in human head-and-neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kappaB Head Neck 22 2000 748 759
32. H. Van Remmen, M.D. Williams, Z. Guo Knockout mice heterozygous for Sod2 show alterations in cardiac mitochondrial function and apoptosis Am J Physiol Heart Circ Physiol 281 2001 H1422 H1432
33. S. Fulda, E. Meyer, K.M. Debatin Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression Cancer Res 60 2000 3947 3956
34. M.R. Sprick, M.A. Weigand, E. Rieser FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2 Immunity 12 2000 599 609
35. E. Chalaux, T. Lopez-Rovira, J.L. Rosa A zinc-finger transcription factor induced by TGF-beta promotes apoptotic cell death in epithelial Mv1Lu cells FEBS Lett 457 1999 478 482
36. Q. Li, N. Ahuja, P.C. Burger Methylation and silencing of the thrombospondin-1 promoter in human cancer Oncogene 18 1999 3284 3289
37. K. Charalabopoulos, A. Gogali, O.K. Kostoula Cadherin superfamily of adhesion molecules in primary lung cancer Exp Oncol 26 2004 256 260
38. J.T. Tran, A. Rosengarth, H. Luecke Cloning, purification and crystallization of full-length human annexin 2 Acta Crystallogr D Biol Crystallogr 58 2002 1854 1857
39. J.Y. Roh, J.R. Stanley Intracellular domain of desmoglein 3 (pemphigus vulgaris antigen) confers adhesive function on the extracellular domain of E-cadherin without binding catenins J Cell Biol 128 1995 939 947
40. M.W. Renshaw, D. Toksoz, M.A. Schwartz Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase J Biol Chem 271 1996 21691 21694