Validation of high-affinity binding sites for succinic acid through distinguishable binding of gamma-hydroxybutyric acid receptor-specific NCS 382 antipodes

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 23, 2008, Pages 6290-6292

  Molnár, Tünde ^a   Visy, Júlia ^a   Simon, Ágnes ^a   Moldvai, István ^a   Temesvári Major, Eszter ^a   Dörnyei, Gábor ^a   Fekete, Erzsébet Kútiné ^a   Kardos, Julianna ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

Author keywords

Gamma hydroxybutyric acid (GHB); NCS 382; Succinic acid

Indexed keywords

4 HYDROXYBUTYRIC ACID; 6,7,8,9 TETRAHYDRO 5 HYDROXY 5H BENZOCYCLOHEPT 6 YLIDENE ACETIC ACID; ACETIC ACID DERIVATIVE; RECEPTOR SUBTYPE; SUCCINIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; ENANTIOSELECTIVITY; RECEPTOR BINDING; STRUCTURE ANALYSIS; SYNAPTIC MEMBRANE; VALIDATION STUDY;

ANIMALS; BENZOCYCLOHEPTENES; BINDING SITES; BINDING, COMPETITIVE; BRAIN; HYDROXYBUTYRATES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; STEREOISOMERISM; SUCCINIC ACID;

RATTUS;

EID: 55549097079     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.08.083     Document Type: Article

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