Gαq reduces cAMP production by decreasing Gαs protein abundance

Biochemical and Biophysical Research Communications

Volumn 377, Issue 2, 2008, Pages 679-684

  Tang, Tong ^a,b   Gao, Mei Hua ^a,b   Miyanohara, Atsushi ^c   Hammond, H Kirk ^a,b  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Abiquitination; Akt; cAMP; G protein; Proteasomal degradation

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR; ANGIOTENSIN II; CYCLIC AMP; DIACYLGLYCEROL; ENDOTHELIN 1; ENDOTHELIN 1A; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INOSITOL 1,4,5 TRISPHOSPHATE; MEMBRANE RECEPTOR; PROTEASOME; PROTEIN KINASE B; PROTEIN MDM2; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR; MDM2 PROTEIN, MOUSE; MESSENGER RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; UBIQUITINATION; ANIMAL; BIOSYNTHESIS; GENETICS; METABOLISM; TRANSGENIC MOUSE;

ANIMALS; CYCLIC AMP; ENZYME ACTIVATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MICE; MICE, TRANSGENIC; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; RECEPTORS, ADRENERGIC, BETA; RNA, MESSENGER; UBIQUITINATION;

EID: 55549091689     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.10.054     Document Type: Article

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