Nucleoside transport mechanisms in the pigmented rabbit conjunctiva

Investigative Ophthalmology and Visual Science

Volumn 39, Issue 2, 1998, Pages 372-377

  Hosoya, Ken Ichi ^a,b   Horibe, Yoshihide ^a   Kim, Kwang Jin ^a,c   Lee, Vincent H L ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b TOHOKU UNIVERSITY   (Japan)

^c School of Pharmacy ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 (2 BROMOVINYL) 2' DEOXYURIDINE; ADENOSINE; DEOXYURIDINE; GUANOSINE; IDOXURIDINE; INOSINE; NITROBENZYLTHIOINOSINE; PHLORIZIN; SODIUM ION; THYMIDINE; URIDINE;

ANIMAL TISSUE; ARTICLE; CONJUNCTIVA; CONTROLLED STUDY; MALE; MICHAELIS CONSTANT; NONHUMAN; NUCLEOSIDE TRANSPORT; PRIORITY JOURNAL; RABBIT; SHORT CIRCUIT CURRENT;

ANIMALS; BIOLOGICAL TRANSPORT; CONJUNCTIVA; ELECTROPHYSIOLOGY; KINETICS; MALE; PATCH-CLAMP TECHNIQUES; PURINE NUCLEOTIDES; RABBITS; SODIUM; URIDINE;

EID: 0031892557     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. +-nucleoside transport in brush border membrane vesicles from human kidney. Biochim Biophys Acta. 1993;1149:202-208.
2. Williams TC, Jarvis SM. Multiple sodium-dependent nucleoside transport systems in bovine renal brush-border membrane vesicles. Biochem J. 1991;274:27-33.
3. +-dependent nucleoside transport system of rat intestine in isolated oocytes of xenopus laevis. J Biol Chem. 1993;268:20613-20619.
4. Wu X, Gutierrez MM, Giacomini KM. Further characterization of the sodium-dependent nucleoside transporter (N3) in choroid plexus from rabbit. Biochim Biophys Acta. 1994;1191:190-196.
5. Plagemann PGW, Wohlhueter RM, Woffendin C. Nucleoside and nucleobase transport in animal cells. Biochim Biophys Acta. 1988; 947:405-443.
6. Vijayalakshmi D, Belt JA. Sodium-dependent nucleoside transport in mouse intestinal epithelial cells. J Biol Chem. 1988;263:19419-19423.
7. Wu X, Yuan G, Brett CM, Hui AC, Giacomini KM. Sodium-dependent nucleoside transport in choroid plexus from rabbit. J Biol Chem. 1992;267:8813-8818.
8. Schaeffer JM, Anderson SM. Nucleoside uptake by rat retina cells. Life Sci. 1981;29:939-946.
9. Ahmed I, Patton TF. Disposition of timolol and inulin in the rabbit eye following corneal versus non-corneal absorption. Int J Pharm. 1987;38:9-21.
10. Sincholle D, Conduzorgues JP, Mbatchi D, Masse JP. Corneal penetration and metabolism of the antitherapeutic 5-iodo2′-deoxyuridine. Curr Eye Res. 1985;4:627-629.
11. Maudgal PC, De Clercq E, Missotten L. Efficacy of bromovinyldeoxyuridine in the treatment of herpes simplex virus and varicella-zoster virus eye infections. Antiviral Res. 1994;4:281-291.
12. Belt JA, Marina N Mex, Phelps DA, Crawford CR. Nucleoside transport in normal and neoplastic cell. Adv Enzyme Regul. 1993; 33:235-252.
13. Schenk M, Hegazy E, Pino VL. Uridine uptake by isolated epithelial cells of guinea pig. Biochim Biophys Acta. 1984;805:370-374.
14. Kompella UB, Kim KJ, Lee VHL. Active chloride transport in the pigmented rabbit conjunctiva. Curr Eye Res. 1993;12:1041-1048.
15. +-dependent L-arginine transport in the pigmented rabbit conjunctiva. Exp Eye Res. 1997; 65:547-553.
16. Jarvis SM. Characterization of sodium-dependent nucleoside transport in rabbit intestinal brush-border vesicles. Biocbim Biophys Acta. 1989;979:132-138.
17. Gutierrez MM, Brett CM, Ott RJ, Hui AC, Giacomini KM. Nucleoside transport in brush border membrane vesicles from human kidney. Biochim Biophys Acta. 1992;1105:1-9.
18. Fang X, Mowles DA, Young JD, Cass CE. Functional characterization of a recombinant sodium-dependent nucleoside transporter with selectivity for pyrimidine nucleosides (cNT1rat) by transient expression in cultured mammalian cells. Biochem J. 1996;317: 457-465.
19. Griffith DA, Doherty AJ, Jarvis SM. Nucleoside transport in cultured LLC-PK1 epithelia. Biochim Biophys Acta. 1992;1106:303-310.
20. +-glucose cotransport to the short-circuit current in the pigmented rabbit conjunctiva. Curr Eye Res. 1996;15:447-451.
21. Brett CM, Washington CB, Ott RJ, Gutierrez MM, Giacomini KM. Interaction of nucleoside analogues with the sodium-nucleoside transport system in brush border membrane vesicles from human kidney. Pharm Res. 1993;10:423-426.
22. Narurkar MM, Mitra AK. Prodrug of 5-iodo-2′-deoxyuridine for enhanced ocular transport. Pharm Res. 1989;6:887-891.
23. Power WJ, Benedict-Smith A, Hillery M, Brady K, Collum LM. Randomised double-blind trial of bromovinyldeoxyuridine (BVDU) and trifluorothymidine (TFT) in dendritic corneal ulceration. Br J Ophthalmol. 1991;75:649-651.
24. Hosoya K, Lee VHL. Cidofovir transport in the pigmented rabbit conjunctiva. Curr Eye Res. 1997;16:693-697.